| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | diethyl 2-[(dimethoxyphosphoryl)sulfanyl]succinate 5.06 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN009_HEPG2_24H:G21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 5.57547 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 5.21807 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.79372 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.70657 |
| NOTCH1 | notch 1 | 4.6593 |
| DIPK1A | divergent protein kinase domain 1A | 4.48867 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.27298 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.18727 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.04263 |
| MAP7 | microtubule-associated protein 7 | 3.74573 |
| HOXA10 | homeobox A10 | 3.59666 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.56434 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.52526 |
| PRR15L | proline rich 15-like | 3.36477 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.36399 |
| PFKL | phosphofructokinase, liver | 3.33808 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.21105 |
| SNX7 | sorting nexin 7 | 2.92038 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.71009 |
| RTN2 | reticulon 2 | 2.68879 |
| CHEK2 | checkpoint kinase 2 | 2.49676 |
| TRIM13 | tripartite motif containing 13 | 2.47103 |
| TUBB4A | tubulin, beta 4A class IVa | 2.43184 |
| INTS8 | integrator complex subunit 8 | 2.36852 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.36675 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 2.18882 |
| GATD3 | glutamine amidotransferase class 1 domain containing 3 | 2.16315 |
| TULP4 | tubby like protein 4 | 2.11827 |
| MTPAP | mitochondrial poly(A) polymerase | 2.08635 |
| FGGY | FGGY carbohydrate kinase domain containing | 2.05088 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 2.00315 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLT1B | golgi transport 1B | -9.31545 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -9.26056 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.25686 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.06002 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.89976 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -4.77671 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.67677 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.55457 |
| CSK | c-src tyrosine kinase | -4.3854 |
| GNAS | GNAS complex locus | -4.23695 |
| CCNB2 | cyclin B2 | -4.20175 |
| LDHD | lactate dehydrogenase D | -4.09391 |
| RECQL | RecQ helicase-like | -2.99894 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.8269 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.49831 |
| TP53RK | TP53 regulating kinase | -2.42369 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -2.31065 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -2.23346 |
| ESYT1 | extended synaptotagmin-like protein 1 | -2.22223 |
| CLTB | clathrin, light chain B | -2.16803 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.05228 |
| EGF | epidermal growth factor | -2.04105 |
| PLA1A | phospholipase A1 member A | -2.02528 |
| TWF2 | twinfilin actin binding protein 2 | -2.02476 |
