CRCGN009_HEPG2_24H:G23 Gene Set
Genes
47 genes differentially expressed following the CRCGN009_HEPG2_24H:G23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.53823
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
5.15191
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
5.08537
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.73439
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
4.4978
|
|
H2BC21
|
H2B clustered histone 21
|
4.47223
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.37538
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.32623
|
|
CYCS
|
cytochrome c, somatic
|
4.11778
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.39938
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
3.30049
|
|
GPATCH8
|
G patch domain containing 8
|
3.28247
|
|
MEST
|
mesoderm specific transcript
|
3.25643
|
|
UBQLN2
|
ubiquilin 2
|
3.2297
|
|
SOX2
|
SRY (sex determining region Y)-box 2
|
3.05218
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.04834
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.86606
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.42415
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.39789
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.32416
|
|
STXBP2
|
syntaxin binding protein 2
|
2.21389
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-8.49906
|
|
CD320
|
CD320 molecule
|
-4.79442
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.77979
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.68457
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.4616
|
|
CCNB2
|
cyclin B2
|
-4.32465
|
|
HYOU1
|
hypoxia up-regulated 1
|
-3.9435
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-3.59079
|
|
GNAS
|
GNAS complex locus
|
-3.5729
|
|
VAT1
|
vesicle amine transport 1
|
-3.4278
|
|
TLR4
|
toll-like receptor 4
|
-3.41745
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.37779
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.23501
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.09285
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.92489
|
|
CSK
|
c-src tyrosine kinase
|
-2.55631
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.48539
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.44891
|
|
TUBB6
|
tubulin, beta 6 class V
|
-2.34023
|
|
HAGH
|
hydroxyacylglutathione hydrolase
|
-2.28556
|
|
LUC7L
|
LUC7-like (S. cerevisiae)
|
-2.26069
|
|
CCNH
|
cyclin H
|
-2.19705
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.17427
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.03753
|
|
CACNG3
|
calcium channel, voltage-dependent, gamma subunit 3
|
-2.03396
|
|
SPSB3
|
splA/ryanodine receptor domain and SOCS box containing 3
|
-2.01377
|
