CRCGN009_HEPG2_24H:G24 Gene Set
Genes
51 genes differentially expressed following the CRCGN009_HEPG2_24H:G24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
4.99581
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.54043
|
|
UBQLN2
|
ubiquilin 2
|
4.51221
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.50201
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.43975
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.20973
|
|
CYCS
|
cytochrome c, somatic
|
4.20795
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.90303
|
|
MAP7
|
microtubule-associated protein 7
|
3.32063
|
|
GATA2
|
GATA binding protein 2
|
3.2212
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.18741
|
|
LCN2
|
lipocalin 2
|
3.14346
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.11712
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.8711
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.61706
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.50131
|
|
CHN1
|
chimerin 1
|
2.41198
|
|
UTP18
|
UTP18 small subunit (SSU) processome component homolog (yeast)
|
2.39386
|
|
TATDN2
|
TatD DNase domain containing 2
|
2.30244
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.28733
|
|
XK
|
X-linked Kx blood group
|
2.25629
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.13654
|
|
BTN3A2
|
butyrophilin, subfamily 3, member A2
|
2.03746
|
|
PCDHB11
|
protocadherin beta 11
|
2.02053
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-7.124
|
|
PEG10
|
paternally expressed 10
|
-5.33163
|
|
TRIB3
|
tribbles pseudokinase 3
|
-5.18198
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.19326
|
|
DNM1L
|
dynamin 1-like
|
-4.16211
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-4.15531
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.09437
|
|
CCNB2
|
cyclin B2
|
-3.77476
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.51656
|
|
EGF
|
epidermal growth factor
|
-3.39234
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.2782
|
|
HYOU1
|
hypoxia up-regulated 1
|
-3.20779
|
|
ZNF586
|
zinc finger protein 586
|
-3.07085
|
|
CPNE3
|
copine III
|
-3.03536
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.88421
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.79935
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.28629
|
|
SERPINF2
|
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
|
-2.17808
|
|
STUM
|
stum, mechanosensory transduction mediator homolog
|
-2.05988
|
|
SPIB
|
Spi-B transcription factor (Spi-1/PU.1 related)
|
-2.04421
|
|
RND1
|
Rho family GTPase 1
|
-2.0403
|
|
CLSTN3
|
calsyntenin 3
|
-2.0317
|
|
MAGEA9B
|
melanoma antigen family A9B
|
-2.02985
|
|
CSRNP2
|
cysteine-serine-rich nuclear protein 2
|
-2.02175
|
|
BAZ2B
|
bromodomain adjacent to zinc finger domain, 2B
|
-2.01983
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
-2.01508
|
|
FGB
|
fibrinogen beta chain
|
-2.00361
|