CRCGN009_HEPG2_24H:H01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hexachlorophene 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1046 genes differentially expressed following the CRCGN009_HEPG2_24H:H01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
TXNRD1 thioredoxin reductase 1 10.0
LCN2 lipocalin 2 10.0
STX1A syntaxin 1A (brain) 9.5809
FOSL1 FOS-like antigen 1 9.57842
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 9.27438
ZFP36 ZFP36 ring finger protein 8.83853
TIMP2 TIMP metallopeptidase inhibitor 2 8.72344
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 8.44674
TRIB3 tribbles pseudokinase 3 8.25683
INPP1 inositol polyphosphate-1-phosphatase 8.0796
ABHD4 abhydrolase domain containing 4 7.99545
HSPA1A heat shock 70kDa protein 1A 7.10946
GFPT1 glutamine--fructose-6-phosphate transaminase 1 7.01377
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 6.86912
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 6.7371
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 6.63579
SHB Src homology 2 domain containing adaptor protein B 6.6197
IGFBP3 insulin-like growth factor binding protein 3 6.42125
MICALL1 MICAL-like 1 6.33381
SQSTM1 sequestosome 1 6.22455
GFOD1 glucose-fructose oxidoreductase domain containing 1 6.12475
SQOR sulfide quinone oxidoreductase 5.98966
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 5.93556
CASC3 cancer susceptibility candidate 3 5.8066
NPC1 Niemann-Pick disease, type C1 5.77506
BAG3 BCL2-associated athanogene 3 5.74072
MMP1 matrix metallopeptidase 1 5.73943
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 5.65182
BIRC2 baculoviral IAP repeat containing 2 5.62919
EGR1 early growth response 1 5.56372
CDK7 cyclin-dependent kinase 7 5.51735
CNPY3 canopy FGF signaling regulator 3 5.43781
TNIP1 TNFAIP3 interacting protein 1 5.379
KIFBP kinesin family binding protein 5.37435
AARS1 alanyl-tRNA synthetase 1 5.333
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 5.09912
MYLK myosin light chain kinase 5.07978
H2BC12 H2B clustered histone 12 5.04305
FHL2 four and a half LIM domains 2 4.9929
ASCC3 activating signal cointegrator 1 complex subunit 3 4.97881
TICAM1 toll-like receptor adaptor molecule 1 4.93733
RGS2 regulator of G-protein signaling 2 4.89012
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.84137
PRKCD protein kinase C, delta 4.83129
KDM5A lysine (K)-specific demethylase 5A 4.77983
GRB10 growth factor receptor-bound protein 10 4.69236
DDIT4 DNA-damage-inducible transcript 4 4.64045
NUP58 nucleoporin 58 4.62721
TRIB1 tribbles pseudokinase 1 4.61781
TERF2IP telomeric repeat binding factor 2, interacting protein 4.6138
TBPL1 TBP-like 1 4.5837
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 4.55274
PTK2 protein tyrosine kinase 2 4.4921
STK10 serine/threonine kinase 10 4.4804
RAP1GAP RAP1 GTPase activating protein 4.47943
MYC v-myc avian myelocytomatosis viral oncogene homolog 4.46903
LOC128125814 uncharacterized LOC128125814 4.39554
TESK1 testis-specific kinase 1 4.38179
CSNK1E casein kinase 1, epsilon 4.37231
ANO1 anoctamin 1, calcium activated chloride channel 4.36958
ANO10 anoctamin 10 4.3545
NR1H2 nuclear receptor subfamily 1, group H, member 2 4.34215
SMAD3 SMAD family member 3 4.21046
JUN jun proto-oncogene 4.2016
IER3 immediate early response 3 4.18145
DUSP8 dual specificity phosphatase 8 4.13459
FOXJ3 forkhead box J3 4.13149
STAP2 signal transducing adaptor family member 2 4.07455
PTPN12 protein tyrosine phosphatase, non-receptor type 12 4.02461
ALAS1 5'-aminolevulinate synthase 1 4.01948
ERBIN erbb2 interacting protein 4.01237
CAB39 calcium binding protein 39 4.00933
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 3.96876
JOSD1 Josephin domain containing 1 3.94524
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 3.92078
MVP major vault protein 3.90649
GOLT1B golgi transport 1B 3.87997
LRP10 low density lipoprotein receptor-related protein 10 3.75594
KEAP1 kelch-like ECH-associated protein 1 3.72237
MBNL1 muscleblind-like splicing regulator 1 3.72084
GPC1 glypican 1 3.69339
SMNDC1 survival motor neuron domain containing 1 3.67096
RAB11FIP2 RAB11 family interacting protein 2 (class I) 3.61346
ZBTB10 zinc finger and BTB domain containing 10 3.60803
TRIM13 tripartite motif containing 13 3.60187
CTSL cathepsin L 3.59884
RAB11FIP1 RAB11 family interacting protein 1 (class I) 3.56125
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 3.52984
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 3.50723
TP53BP2 tumor protein p53 binding protein 2 3.45917
MGLL monoglyceride lipase 3.45715
C2CD2 C2 calcium-dependent domain containing 2 3.38143
GTPBP2 GTP binding protein 2 3.37892
IFRD1 interferon-related developmental regulator 1 3.37827
DNM1L dynamin 1-like 3.36288
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 3.33128
YARS1 tyrosyl-tRNA synthetase 1 3.32844
NIBAN1 niban apoptosis regulator 1 3.3273
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 3.3195
ATF3 activating transcription factor 3 3.31574
GARS1 glycyl-tRNA synthetase 1 3.31535
IER5 immediate early response 5 3.28946
SH3GLB1 SH3-domain GRB2-like endophilin B1 3.28517
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 3.2845
CCL2 chemokine (C-C motif) ligand 2 3.26715
MAP7 microtubule-associated protein 7 3.25587
EPS8 epidermal growth factor receptor pathway substrate 8 3.24613
TRAPPC6A trafficking protein particle complex 6A 3.23607
PRR15L proline rich 15-like 3.23043
FBXO7 F-box protein 7 3.22855
VAT1 vesicle amine transport 1 3.22817
CLIP4 CAP-GLY domain containing linker protein family, member 4 3.21642
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 3.21639
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 3.21552
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 3.2143
IL11 interleukin 11 3.19206
SOX4 SRY (sex determining region Y)-box 4 3.16519
SARS1 seryl-tRNA synthetase 1 3.13436
TES testin LIM domain protein 3.12501
LSR lipolysis stimulated lipoprotein receptor 3.11936
ARID4B AT rich interactive domain 4B (RBP1-like) 3.11572
IL4R interleukin 4 receptor 3.11461
KDM3A lysine (K)-specific demethylase 3A 3.10568
PDE8A phosphodiesterase 8A 3.10447
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 3.08568
NPTX2 neuronal pentraxin II 3.07855
SPAG9 sperm associated antigen 9 3.07261
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 3.06939
RUSC2 RUN and SH3 domain containing 2 3.06853
ZMIZ1 zinc finger, MIZ-type containing 1 3.05468
RNF24 ring finger protein 24 3.05375
YIPF3 Yip1 domain family, member 3 3.05354
PHF20L1 PHD finger protein 20-like 1 3.03656
MSN moesin 3.03111
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 3.02
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 3.01895
DCAF10 DDB1 and CUL4 associated factor 10 3.0109
CCNA1 cyclin A1 3.00925
LARP6 La ribonucleoprotein domain family, member 6 3.00879
IL37 interleukin 37 2.98625
EFS embryonal Fyn-associated substrate 2.98534
H2BC21 H2B clustered histone 21 2.97151
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.95234
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.95137
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.94585
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.93548
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.93059
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.92531
MOK MOK protein kinase 2.92351
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.9233
MAP7D1 MAP7 domain containing 1 2.91329
RNF103-CHMP3 RNF103-CHMP3 readthrough 2.91245
NDEL1 nudE neurodevelopment protein 1-like 1 2.91205
REL v-rel avian reticuloendotheliosis viral oncogene homolog 2.91151
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.9076
KAT6A K(lysine) acetyltransferase 6A 2.90732
PTPRK protein tyrosine phosphatase, receptor type, K 2.90275
SERINC1 serine incorporator 1 2.89965
ANKRD11 ankyrin repeat domain 11 2.89545
CHD1 chromodomain helicase DNA binding protein 1 2.88947
HSPA6 heat shock 70kDa protein 6 (HSP70B') 2.88063
MTERF3 mitochondrial transcription termination factor 3 2.86805
RAI14 retinoic acid induced 14 2.86218
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 2.86004
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.8511
RGCC regulator of cell cycle 2.84854
PLK3 polo-like kinase 3 2.83703
BYSL bystin-like 2.82322
CSRNP2 cysteine-serine-rich nuclear protein 2 2.82272
CCDC92 coiled-coil domain containing 92 2.81754
RGS10 regulator of G-protein signaling 10 2.81344
SH2B3 SH2B adaptor protein 3 2.81263
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.80389
PARP6 poly (ADP-ribose) polymerase family, member 6 2.80168
RRAGA Ras-related GTP binding A 2.80115
PKN1 protein kinase N1 2.7976
KLF7 Kruppel-like factor 7 (ubiquitous) 2.79236
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.78813
RTN4 reticulon 4 2.78733
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.77784
STXBP5L syntaxin binding protein 5-like 2.76825
MAPK13 mitogen-activated protein kinase 13 2.76639
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.76444
TARS1 threonyl-tRNA synthetase 1 2.76223
MTFR1 mitochondrial fission regulator 1 2.7597
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.75498
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.74573
BPI bactericidal/permeability-increasing protein 2.73131
EPN3 epsin 3 2.72936
ZBTB35 zinc finger and BTB domain containing 35 2.72777
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 2.72285
GPR87 G protein-coupled receptor 87 2.72129
MYH9 myosin, heavy chain 9, non-muscle 2.71238
EPHA3 EPH receptor A3 2.71218
TLK2 tousled-like kinase 2 2.69804
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.69717
RSF1 remodeling and spacing factor 1 2.69053
KRT86 keratin 86, type II 2.68822
MARK4 MAP/microtubule affinity-regulating kinase 4 2.6833
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 2.67975
POMZP3 POM121 and ZP3 fusion 2.67415
TSC22D1 TSC22 domain family, member 1 2.67269
TBC1D15 TBC1 domain family, member 15 2.66307
ZNF574 zinc finger protein 574 2.66092
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 2.65929
HSPB1 heat shock 27kDa protein 1 2.65401
SNX16 sorting nexin 16 2.65342
BANP BTG3 associated nuclear protein 2.64874
PHC2 polyhomeotic homolog 2 (Drosophila) 2.63743
KDM6B lysine (K)-specific demethylase 6B 2.63574
STC1 stanniocalcin 1 2.63515
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.63477
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.63252
CYTH2 cytohesin 2 2.63224
MAP1B microtubule-associated protein 1B 2.62659
FASTKD5 FAST kinase domains 5 2.62659
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.62036
KIAA0408 KIAA0408 2.61734
UBAP1 ubiquitin associated protein 1 2.60534
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.59788
ARID5B AT rich interactive domain 5B (MRF1-like) 2.59594
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.59442
FRS2 fibroblast growth factor receptor substrate 2 2.59249
UBQLN2 ubiquilin 2 2.58143
H2BC17 H2B clustered histone 17 2.57119
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.57031
RIPK4 receptor-interacting serine-threonine kinase 4 2.5703
MAPK12 mitogen-activated protein kinase 12 2.55988
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.55974
RNF10 ring finger protein 10 2.55489
MAPK8 mitogen-activated protein kinase 8 2.55454
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.55206
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.54829
GADD45A growth arrest and DNA-damage-inducible, alpha 2.54811
GCC1 GRIP and coiled-coil domain containing 1 2.54803
STX3 syntaxin 3 2.54557
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.53696
TOMM34 translocase of outer mitochondrial membrane 34 2.53334
TXNL4B thioredoxin-like 4B 2.52494
MMP3 matrix metallopeptidase 3 2.52365
TFPI2 tissue factor pathway inhibitor 2 2.52271
YY1AP1 YY1 associated protein 1 2.51435
KLF6 Kruppel-like factor 6 2.49949
KLHL21 kelch-like family member 21 2.49435
PRND prion protein 2 (dublet) 2.49329
DAGLA diacylglycerol lipase, alpha 2.49243
SOCS2 suppressor of cytokine signaling 2 2.48821
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.48547
ASCC1 activating signal cointegrator 1 complex subunit 1 2.48283
TMEM184B transmembrane protein 184B 2.47646
RGS20 regulator of G-protein signaling 20 2.47406
GREM1 gremlin 1, DAN family BMP antagonist 2.4726
HOXA10 homeobox A10 2.46825
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.46733
TSPAN15 tetraspanin 15 2.46196
HSPA1B heat shock 70kDa protein 1B 2.45629
RNF11 ring finger protein 11 2.45334
KRT81 keratin 81, type II 2.44988
ADGRG1 adhesion G protein-coupled receptor G1 2.43746
HPCAL1 hippocalcin-like 1 2.43721
ADRB2 adrenoceptor beta 2, surface 2.43468
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 2.43448
SUN2 Sad1 and UNC84 domain containing 2 2.432
PTGES prostaglandin E synthase 2.43011
PRSS8 protease, serine, 8 2.42828
TFG TRK-fused gene 2.42616
CNTN5 contactin 5 2.41957
NCK1 NCK adaptor protein 1 2.41596
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 2.4148
YME1L1 YME1-like 1 ATPase 2.41386
RUBCN rubicon autophagy regulator 2.41299
ANGPTL2 angiopoietin-like 2 2.41256
GLI2 GLI family zinc finger 2 2.40786
LPAR2 lysophosphatidic acid receptor 2 2.40596
SIRT2 sirtuin 2 2.40417
SMIM44 small integral membrane protein 44 2.40228
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 2.39863
CAMTA2 calmodulin binding transcription activator 2 2.39808
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 2.39528
AOC2 amine oxidase, copper containing 2 (retina-specific) 2.38999
TACR3 tachykinin receptor 3 2.38782
PAEP progestagen-associated endometrial protein 2.38761
AGO2 argonaute RISC catalytic component 2 2.38217
EXOC6B exocyst complex component 6B 2.3807
HLA-DRA major histocompatibility complex, class II, DR alpha 2.3798
HSPH1 heat shock 105kDa/110kDa protein 1 2.37954
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 2.37845
DCTN4 dynactin 4 (p62) 2.37761
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 2.37111
ZFP69B ZFP69 zinc finger protein B 2.37073
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 2.36939
RYBP RING1 and YY1 binding protein 2.36677
ELF4 E74-like factor 4 (ets domain transcription factor) 2.36267
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 2.36105
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.35812
RHOG ras homolog family member G 2.3528
ZNF12 zinc finger protein 12 2.35248
STXBP1 syntaxin binding protein 1 2.35147
JMJD1C jumonji domain containing 1C 2.34998
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.34964
TFE3 transcription factor binding to IGHM enhancer 3 2.33937
RND3 Rho family GTPase 3 2.33804
RAB9A RAB9A, member RAS oncogene family 2.33143
HPSE heparanase 2.32838
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.32066
ZFAND1 zinc finger, AN1-type domain 1 2.31859
UFM1 ubiquitin-fold modifier 1 2.31717
IST1 increased sodium tolerance 1 homolog (yeast) 2.31688
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.31488
IL2 interleukin 2 2.31416
SNAI1 snail family zinc finger 1 2.306
ZFAND3 zinc finger, AN1-type domain 3 2.30438
TEAD3 TEA domain family member 3 2.30336
MAN2A1 mannosidase, alpha, class 2A, member 1 2.30254
FXYD5 FXYD domain containing ion transport regulator 5 2.30109
RBM22 RNA binding motif protein 22 2.30074
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.30011
LHCGR luteinizing hormone/choriogonadotropin receptor 2.29865
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 2.29755
MBNL2 muscleblind-like splicing regulator 2 2.29741
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.29645
NKAIN1 Na+/K+ transporting ATPase interacting 1 2.2962
ATF4 activating transcription factor 4 2.29211
FBXW4 F-box and WD repeat domain containing 4 2.29205
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.28977
SNAI2 snail family zinc finger 2 2.28826
H2BC4 H2B clustered histone 4 2.28802
MMP8 matrix metallopeptidase 8 2.28468
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 2.27791
ZBTB17 zinc finger and BTB domain containing 17 2.26894
LRRC8E leucine rich repeat containing 8 family, member E 2.26582
LCOR ligand dependent nuclear receptor corepressor 2.26576
CDCP1 CUB domain containing protein 1 2.26553
AKAP5 A kinase (PRKA) anchor protein 5 2.2646
UNC13A unc-13 homolog A (C. elegans) 2.26459
RFX3 regulatory factor X, 3 (influences HLA class II expression) 2.26443
SEC24A SEC24 family member A 2.26321
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 2.26273
EIF4A2 eukaryotic translation initiation factor 4A2 2.2627
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.25722
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2.25111
KITLG KIT ligand 2.25049
MLPH melanophilin 2.24635
USPL1 ubiquitin specific peptidase like 1 2.24624
RIOK3 RIO kinase 3 2.2437
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.24312
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.24099
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.23748
PLA2G2F phospholipase A2, group IIF 2.2371
NRDE2 NRDE-2, necessary for RNA interference, domain containing 2.23693
TMEM158 transmembrane protein 158 (gene/pseudogene) 2.2365
GOLT1A golgi transport 1A 2.23516
KCMF1 potassium channel modulatory factor 1 2.23382
DCP1A decapping mRNA 1A 2.22385
ELOVL4 ELOVL fatty acid elongase 4 2.22319
IER2 immediate early response 2 2.22044
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 2.21886
CLDN4 claudin 4 2.2182
MARK2 MAP/microtubule affinity-regulating kinase 2 2.21604
ZNF410 zinc finger protein 410 2.21379
TRIM8 tripartite motif containing 8 2.21276
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.21253
SIRT1 sirtuin 1 2.21154
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 2.21024
PELO pelota homolog (Drosophila) 2.20876
USH2A Usher syndrome 2A (autosomal recessive, mild) 2.2016
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 2.20105
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 2.20077
LAMB4 laminin, beta 4 2.19722
XPOT exportin, tRNA 2.19154
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 2.19032
ZNF804A zinc finger protein 804A 2.18804
IGF1R insulin-like growth factor 1 receptor 2.18609
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.18489
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2.18357
TMC5 transmembrane channel-like 5 2.1829
LIF leukemia inhibitory factor 2.18252
CLK3 CDC-like kinase 3 2.18011
OR1E1 olfactory receptor, family 1, subfamily E, member 1 2.17976
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.17841
ZBTB43 zinc finger and BTB domain containing 43 2.17759
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.1747
MCHR1 melanin-concentrating hormone receptor 1 2.17438
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like 2.17249
CRABP2 cellular retinoic acid binding protein 2 2.17033
SLC38A2 solute carrier family 38, member 2 2.16944
SPIN2A spindlin family, member 2A 2.16824
SBDS Shwachman-Bodian-Diamond syndrome 2.16656
PTPN14 protein tyrosine phosphatase, non-receptor type 14 2.16649
ITGA9 integrin, alpha 9 2.16478
TGFA transforming growth factor, alpha 2.16384
TBC1D30 TBC1 domain family, member 30 2.16199
DEFA4 defensin, alpha 4, corticostatin 2.16095
TTLL4 tubulin tyrosine ligase-like family member 4 2.15983
ZNF585B zinc finger protein 585B 2.15891
ZNF146 zinc finger protein 146 2.15776
TJAP1 tight junction associated protein 1 (peripheral) 2.15522
ZNF549 zinc finger protein 549 2.1531
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough 2.15169
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 2.15163
SCNN1B sodium channel, non voltage gated 1 beta subunit 2.15038
FABP2 fatty acid binding protein 2, intestinal 2.14815
CSNK1G3 casein kinase 1, gamma 3 2.14776
NECAP1 NECAP endocytosis associated 1 2.14702
FBXL7 F-box and leucine-rich repeat protein 7 2.14668
PLPP6 phospholipid phosphatase 6 2.14401
ZNF654 zinc finger protein 654 2.14309
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 2.14278
SLC44A4 solute carrier family 44, member 4 2.14071
RIN3 Ras and Rab interactor 3 2.13505
DRD1 dopamine receptor D1 2.13116
MAP3K13 mitogen-activated protein kinase kinase kinase 13 2.1308
FEZF2 FEZ family zinc finger 2 2.12859
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 2.12816
PHF20 PHD finger protein 20 2.12816
RBM6 RNA binding motif protein 6 2.12559
H2AC7 H2A clustered histone 7 2.12468
SYNJ2 synaptojanin 2 2.12288
KCTD9 potassium channel tetramerization domain containing 9 2.12153
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.1207
FCMR Fc fragment of IgM receptor 2.1205
SPON2 spondin 2, extracellular matrix protein 2.12021
CEP170B centrosomal protein 170B 2.11988
NT5E 5'-nucleotidase, ecto (CD73) 2.11926
MLNR motilin receptor 2.11895
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 2.11513
KIAA0513 KIAA0513 2.11503
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.11451
RAB3B RAB3B, member RAS oncogene family 2.11201
ANXA11 annexin A11 2.11174
SDCBP syndecan binding protein (syntenin) 2.1115
UNC5B unc-5 homolog B (C. elegans) 2.11106
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.11103
CTSD cathepsin D 2.11063
CCNJL cyclin J-like 2.10951
C6ORF89 chromosome 6 open reading frame 89 2.10923
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.10833
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 2.10678
PDZD8 PDZ domain containing 8 2.10626
ZYX zyxin 2.10601
NHLH1 nescient helix loop helix 1 2.10433
PCDHA9 protocadherin alpha 9 2.10331
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 2.10321
EDN1 endothelin 1 2.10262
MACO1 macoilin 1 2.10195
ANKRD10 ankyrin repeat domain 10 2.1003
RB1CC1 RB1-inducible coiled-coil 1 2.09644
IL7R interleukin 7 receptor 2.09133
NFE2L2 nuclear factor, erythroid 2-like 2 2.08981
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 2.08873
HBP1 HMG-box transcription factor 1 2.08732
ZNF451 zinc finger protein 451 2.0873
ADAM8 ADAM metallopeptidase domain 8 2.08131
CGRRF1 cell growth regulator with ring finger domain 1 2.08099
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.08004
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 2.07934
PAQR5 progestin and adipoQ receptor family member V 2.0764
ST18 suppression of tumorigenicity 18, zinc finger 2.07328
RRAGC Ras-related GTP binding C 2.07287
RGPD2 RANBP2-like and GRIP domain containing 2 2.07209
H2AC6 H2A clustered histone 6 2.07201
CYSLTR1 cysteinyl leukotriene receptor 1 2.07156
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.07136
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 2.07087
CST8 cystatin 8 (cystatin-related epididymal specific) 2.07083
CRK v-crk avian sarcoma virus CT10 oncogene homolog 2.06764
CCDC186 coiled-coil domain containing 186 2.0668
MMP13 matrix metallopeptidase 13 2.06397
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 2.06245
TENT4A terminal nucleotidyltransferase 4A 2.06101
ATOSB atos homolog B 2.0606
EIF3L eukaryotic translation initiation factor 3, subunit L 2.0604
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 2.06029
PLAUR plasminogen activator, urokinase receptor 2.05921
GRIK3 glutamate receptor, ionotropic, kainate 3 2.05676
LAPTM5 lysosomal protein transmembrane 5 2.05468
AFF4 AF4/FMR2 family, member 4 2.05392
CDH9 cadherin 9, type 2 (T1-cadherin) 2.05017
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 2.05017
ZNF550 zinc finger protein 550 2.04622
FRMPD4 FERM and PDZ domain containing 4 2.04578
VEZT vezatin, adherens junctions transmembrane protein 2.04361
OSBP oxysterol binding protein 2.04267
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.04233
MCPH1 microcephalin 1 2.04217
HSPA9 heat shock 70kDa protein 9 (mortalin) 2.0403
IMPG1 interphotoreceptor matrix proteoglycan 1 2.04018
WIPF1 WAS/WASL interacting protein family, member 1 2.0401
OCLN occludin 2.03677
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 2.03534
MPPED1 metallophosphoesterase domain containing 1 2.03529
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.03492
ITCH itchy E3 ubiquitin protein ligase 2.03213
CRX cone-rod homeobox 2.0299
DLX5 distal-less homeobox 5 2.02829
DUSP5 dual specificity phosphatase 5 2.02778
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 2.02609
THBD thrombomodulin 2.02515
ATXN3L ataxin 3-like 2.02328
EVL Enah/Vasp-like 2.02312
AKAP17A A kinase (PRKA) anchor protein 17A 2.02305
CLK4 CDC-like kinase 4 2.0229
RFC2 replication factor C (activator 1) 2, 40kDa 2.02092
MYH15 myosin, heavy chain 15 2.01804
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 2.01796
PHLDA3 pleckstrin homology-like domain, family A, member 3 2.0143
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 2.01382
PCDHB11 protocadherin beta 11 2.01337
POU6F2 POU class 6 homeobox 2 2.01239
ZNG1A Zn regulated GTPase metalloprotein activator 1A 2.01028
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.00916
PLXNB3 plexin B3 2.00915
CTCF CCCTC-binding factor (zinc finger protein) 2.00897
NOTCH1 notch 1 2.00866
CLCF1 cardiotrophin-like cytokine factor 1 2.00771
HTRA1 HtrA serine peptidase 1 2.00595
ZNF81 zinc finger protein 81 2.00544
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 2.00389
IQSEC2 IQ motif and Sec7 domain 2 2.00386
PGAP6 post-GPI attachment to proteins 6 2.00292
HPCAL4 hippocalcin like 4 2.00275
ZNF749 zinc finger protein 749 2.00215
SERTAD2 SERTA domain containing 2 2.00163
FOXO3 forkhead box O3 2.00027
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 2.00021

decreased expression

Symbol Name Standardized Value
B4GAT1 beta-1,4-glucuronyltransferase 1 -10.0
PCCB propionyl CoA carboxylase, beta polypeptide -10.0
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -9.94498
CD320 CD320 molecule -9.91901
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -9.61733
PROS1 protein S (alpha) -9.26256
NT5DC2 5'-nucleotidase domain containing 2 -9.03432
STMN1 stathmin 1 -8.92929
FGFR4 fibroblast growth factor receptor 4 -8.48835
PARP1 poly (ADP-ribose) polymerase 1 -8.29847
ISOC1 isochorismatase domain containing 1 -8.29761
PSRC1 proline/serine-rich coiled-coil 1 -8.11336
CCNA2 cyclin A2 -7.89784
INTS3 integrator complex subunit 3 -7.54362
PLK1 polo-like kinase 1 -7.33061
PGAM4 phosphoglycerate mutase family member 4 -7.31279
HMGA2 high mobility group AT-hook 2 -7.26554
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -7.10953
LBR lamin B receptor -7.09651
UBE2C ubiquitin-conjugating enzyme E2C -7.09231
HACD3 3-hydroxyacyl-CoA dehydratase 3 -6.97395
CDC20 cell division cycle 20 -6.88789
TCTN1 tectonic family member 1 -6.80649
GLOD4 glyoxalase domain containing 4 -6.6881
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -6.68778
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -6.62573
BLCAP bladder cancer associated protein -6.60385
POLR1A polymerase (RNA) I polypeptide A, 194kDa -6.57411
RUVBL1 RuvB-like AAA ATPase 1 -6.50089
CCNB1 cyclin B1 -6.34211
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -6.23612
CDK1 cyclin-dependent kinase 1 -6.19337
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -6.17691
TSEN2 TSEN2 tRNA splicing endonuclease subunit -6.1351
TOP2A topoisomerase (DNA) II alpha 170kDa -6.12253
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -5.94727
TARBP1 TAR (HIV-1) RNA binding protein 1 -5.73728
NUP85 nucleoporin 85kDa -5.72241
BIRC5 baculoviral IAP repeat containing 5 -5.69567
ADI1 acireductone dioxygenase 1 -5.61004
UBE3C ubiquitin protein ligase E3C -5.57902
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -5.57476
NIPSNAP1 nipsnap homolog 1 (C. elegans) -5.44733
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -5.43572
DERA deoxyribose-phosphate aldolase (putative) -5.39751
ZNF274 zinc finger protein 274 -5.37949
LOC124907782 dual specificity protein phosphatase 22 -5.35985
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -5.33888
GTF2A2 general transcription factor IIA, 2, 12kDa -5.3079
CETN3 centrin, EF-hand protein, 3 -5.29586
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -5.21063
AMDHD2 amidohydrolase domain containing 2 -5.19591
GAA glucosidase, alpha; acid -5.16986
TLCD3A TLC domain containing 3A -5.09125
COG7 component of oligomeric golgi complex 7 -5.08572
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -5.03388
CRYZ crystallin, zeta (quinone reductase) -5.01124
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -4.97949
NISCH nischarin -4.97799
ASF1B anti-silencing function 1B histone chaperone -4.96908
AURKB aurora kinase B -4.91795
NLRP2B NLR family pyrin domain containing 2B -4.91165
PGM1 phosphoglucomutase 1 -4.87166
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.86451
ZW10 zw10 kinetochore protein -4.81572
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -4.8121
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -4.76307
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -4.71961
MYCBP MYC binding protein -4.67883
MRPL12 mitochondrial ribosomal protein L12 -4.67709
CBR1 carbonyl reductase 1 -4.63851
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -4.63818
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -4.59991
CDK4 cyclin-dependent kinase 4 -4.56224
ZDHHC6 zinc finger, DHHC-type containing 6 -4.52305
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -4.51112
LAGE3 L antigen family, member 3 -4.49521
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.40284
SKIC8 SKI8 subunit of superkiller complex -4.36436
PRCP prolylcarboxypeptidase (angiotensinase C) -4.33894
HADH hydroxyacyl-CoA dehydrogenase -4.33384
PLA2G15 phospholipase A2, group XV -4.29427
TFDP1 transcription factor Dp-1 -4.28421
AKAP8 A kinase (PRKA) anchor protein 8 -4.23903
TPM1 tropomyosin 1 (alpha) -4.23035
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -4.2276
TRAP1 TNF receptor-associated protein 1 -4.19941
THAP11 THAP domain containing 11 -4.16316
PPIC peptidylprolyl isomerase C (cyclophilin C) -4.1301
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -4.11609
MAT2A methionine adenosyltransferase II, alpha -4.10872
ALDOC aldolase C, fructose-bisphosphate -4.06286
TMEM97 transmembrane protein 97 -4.03931
HAT1 histone acetyltransferase 1 -4.02701
EED embryonic ectoderm development -4.01751
MRPS7 mitochondrial ribosomal protein S7 -3.97595
CCNB2 cyclin B2 -3.96943
MLEC malectin -3.95502
CRTAP cartilage associated protein -3.94143
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.92859
COG4 component of oligomeric golgi complex 4 -3.9279
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -3.92229
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.9171
CD58 CD58 molecule -3.90271
GEMIN6 gem (nuclear organelle) associated protein 6 -3.86885
TSPAN4 tetraspanin 4 -3.83131
TLR4 toll-like receptor 4 -3.82503
CASP3 caspase 3, apoptosis-related cysteine peptidase -3.81443
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.78542
CENPX centromere protein X -3.75792
NFIL3 nuclear factor, interleukin 3 regulated -3.74558
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -3.72298
TSPAN6 tetraspanin 6 -3.68879
CCDC86 coiled-coil domain containing 86 -3.68608
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -3.66992
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -3.6665
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -3.66038
HYOU1 hypoxia up-regulated 1 -3.64505
MIS18A MIS18 kinetochore protein A -3.64204
TUBB6 tubulin, beta 6 class V -3.57807
RPA3 replication protein A3, 14kDa -3.57555
PAGR1 PAXIP1 associated glutamate-rich protein 1 -3.5445
KANSL1 KAT8 regulatory NSL complex subunit 1 -3.54192
CENPM centromere protein M -3.52527
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.52262
MCM10 minichromosome maintenance complex component 10 -3.51573
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.51238
KIF4A kinesin family member 4A -3.49983
DNAAF2 dynein, axonemal, assembly factor 2 -3.46399
ZNF83 zinc finger protein 83 -3.45113
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -3.42378
TRIP13 thyroid hormone receptor interactor 13 -3.41332
TMEM109 transmembrane protein 109 -3.41323
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -3.40241
ANAPC15 anaphase promoting complex subunit 15 -3.402
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.39591
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.39575
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -3.39433
KIF15 kinesin family member 15 -3.39385
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -3.37645
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.36412
PCNA proliferating cell nuclear antigen -3.35421
AURKA aurora kinase A -3.35183
C2CD5 C2 calcium-dependent domain containing 5 -3.3362
WDR77 WD repeat domain 77 -3.32926
EMC9 ER membrane protein complex subunit 9 -3.3127
MRPL17 mitochondrial ribosomal protein L17 -3.30206
NRIP1 nuclear receptor interacting protein 1 -3.29333
ATP5MC1 ATP synthase membrane subunit c locus 1 -3.28583
DENND2D DENN/MADD domain containing 2D -3.27582
GALE UDP-galactose-4-epimerase -3.26239
RBM14-RBM4 RBM14-RBM4 readthrough -3.2623
NENF neudesin neurotrophic factor -3.2576
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -3.25524
NCAPG2 non-SMC condensin II complex, subunit G2 -3.24457
OIP5 Opa interacting protein 5 -3.24097
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.23844
FKTN fukutin -3.23804
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -3.23528
FKBP3 FK506 binding protein 3, 25kDa -3.20069
MELK maternal embryonic leucine zipper kinase -3.19453
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -3.17932
HEATR1 HEAT repeat containing 1 -3.13055
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.12616
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -3.12334
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -3.08189
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) -3.07305
TXLNA taxilin alpha -3.07075
GALK1 galactokinase 1 -3.06229
TRAPPC3 trafficking protein particle complex 3 -3.05904
PMPCA peptidase (mitochondrial processing) alpha -3.05435
MRPL39 mitochondrial ribosomal protein L39 -3.05373
MRPL11 mitochondrial ribosomal protein L11 -3.05151
PEPD peptidase D -3.04162
CARHSP1 calcium regulated heat stable protein 1, 24kDa -3.03542
CDKN3 cyclin-dependent kinase inhibitor 3 -3.02227
ACAA1 acetyl-CoA acyltransferase 1 -3.02164
MRPS16 mitochondrial ribosomal protein S16 -3.01657
MRPL23 mitochondrial ribosomal protein L23 -3.01509
RPIA ribose 5-phosphate isomerase A -3.01393
NR1H3 nuclear receptor subfamily 1, group H, member 3 -3.00003
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.99535
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 -2.99033
SPPL2A signal peptide peptidase like 2A -2.98073
LYRM1 LYR motif containing 1 -2.98058
EXTL2 exostosin-like glycosyltransferase 2 -2.96776
TIPIN TIMELESS interacting protein -2.96603
TMEM126B transmembrane protein 126B -2.9642
DCK deoxycytidine kinase -2.96404
RMI1 RecQ mediated genome instability 1 -2.96326
MRPL16 mitochondrial ribosomal protein L16 -2.95148
ELP4 elongator acetyltransferase complex subunit 4 -2.94293
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.92366
PPP4C protein phosphatase 4, catalytic subunit -2.91783
CDC25B cell division cycle 25B -2.91194
TSPAN3 tetraspanin 3 -2.90771
UNC119B unc-119 homolog B (C. elegans) -2.89692
ELP5 elongator acetyltransferase complex subunit 5 -2.89038
CDK5 cyclin-dependent kinase 5 -2.88606
AGMAT agmatine ureohydrolase (agmatinase) -2.88253
ZDHHC24 zinc finger, DHHC-type containing 24 -2.88081
CBR4 carbonyl reductase 4 -2.87573
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.85346
RPUSD2 RNA pseudouridylate synthase domain containing 2 -2.84342
SNF8 SNF8, ESCRT-II complex subunit -2.83707
PYCR1 pyrroline-5-carboxylate reductase 1 -2.83654
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.83195
KIF14 kinesin family member 14 -2.8251
CHEK2 checkpoint kinase 2 -2.82404
TFB1M transcription factor B1, mitochondrial -2.82391
SOAT2 sterol O-acyltransferase 2 -2.82197
LRRC61 leucine rich repeat containing 61 -2.82012
GCDH glutaryl-CoA dehydrogenase -2.81533
ZWINT ZW10 interacting kinetochore protein -2.79851
CDKN2A cyclin-dependent kinase inhibitor 2A -2.79745
CENPS-CORT CENPS-CORT readthrough -2.79576
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.79274
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.76909
ATP7B ATPase, Cu++ transporting, beta polypeptide -2.76806
GLB1 galactosidase, beta 1 -2.76403
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.75852
CDCA3 cell division cycle associated 3 -2.75372
PDHB pyruvate dehydrogenase (lipoamide) beta -2.7537
PTTG1 pituitary tumor-transforming 1 -2.74375
CENPA centromere protein A -2.73847
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.73333
TMX1 thioredoxin-related transmembrane protein 1 -2.72936
TMEM14A transmembrane protein 14A -2.72903
FIBP fibroblast growth factor (acidic) intracellular binding protein -2.72753
HMGN3 high mobility group nucleosomal binding domain 3 -2.7208
SCARB1 scavenger receptor class B, member 1 -2.71596
COA3 cytochrome c oxidase assembly factor 3 -2.7152
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.71151
TCEAL4 transcription elongation factor A (SII)-like 4 -2.70918
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -2.70782
ATP5MF ATP synthase membrane subunit f -2.70339
RBX1 ring-box 1, E3 ubiquitin protein ligase -2.70183
KIF11 kinesin family member 11 -2.69702
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.69592
CKS1B CDC28 protein kinase regulatory subunit 1B -2.69136
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.67367
VRK1 vaccinia related kinase 1 -2.66854
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.66805
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.66576
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.66562
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.6634
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.66271
TACC3 transforming, acidic coiled-coil containing protein 3 -2.66176
BANF1 barrier to autointegration factor 1 -2.66062
DCPH1 damage control phosphatase 1 -2.65994
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -2.65501
SAP30 Sin3A-associated protein, 30kDa -2.64484
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -2.6448
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 -2.64417
GLRX5 glutaredoxin 5 -2.63113
AMT aminomethyltransferase -2.62905
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.62569
GATD3 glutamine amidotransferase class 1 domain containing 3 -2.6252
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.625
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.62175
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.62047
TEDC2 tubulin epsilon and delta complex 2 -2.61444
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.61281
BMP4 bone morphogenetic protein 4 -2.61238
DHFR dihydrofolate reductase -2.60543
COMMD9 COMM domain containing 9 -2.59858
ABAT 4-aminobutyrate aminotransferase -2.5982
SNX17 sorting nexin 17 -2.59708
GLT8D1 glycosyltransferase 8 domain containing 1 -2.59044
FARSA phenylalanyl-tRNA synthetase, alpha subunit -2.58927
HAUS7 HAUS augmin-like complex, subunit 7 -2.58661
PALB2 partner and localizer of BRCA2 -2.58564
SIRT3 sirtuin 3 -2.58125
MSH6 mutS homolog 6 -2.5761
ARF5 ADP-ribosylation factor 5 -2.56167
TRIM6-TRIM34 TRIM6-TRIM34 readthrough -2.5574
HMGB2 high mobility group box 2 -2.55598
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -2.55557
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.55149
ABHD14A abhydrolase domain containing 14A -2.55077
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.54963
SEPHS1 selenophosphate synthetase 1 -2.54906
QDPR quinoid dihydropteridine reductase -2.54591
G6PC3 glucose 6 phosphatase, catalytic, 3 -2.54066
TRAPPC4 trafficking protein particle complex 4 -2.54018
COMMD8 COMM domain containing 8 -2.54005
CETN2 centrin, EF-hand protein, 2 -2.52212
B9D1 B9 protein domain 1 -2.51868
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -2.51701
PARN poly(A)-specific ribonuclease -2.50998
USP6NL USP6 N-terminal like -2.50664
CDCA8 cell division cycle associated 8 -2.4968
NUP107 nucleoporin 107kDa -2.49652
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.4941
SPIN2B spindlin family, member 2B -2.48996
TUSC2 tumor suppressor candidate 2 -2.48874
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -2.48758
PDCD6 programmed cell death 6 -2.48452
TK1 thymidine kinase 1, soluble -2.48135
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -2.48124
XPO1 exportin 1 -2.47949
RWDD2A RWD domain containing 2A -2.47362
PLA2G2D phospholipase A2, group IID -2.46972
RBBP4 retinoblastoma binding protein 4 -2.46748
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -2.46298
MTCH2 mitochondrial carrier 2 -2.46247
CTSC cathepsin C -2.45921
CKS2 CDC28 protein kinase regulatory subunit 2 -2.45698
HDAC2 histone deacetylase 2 -2.45607
HSPA14 heat shock 70kDa protein 14 -2.45503
KHK ketohexokinase (fructokinase) -2.45459
GAMT guanidinoacetate N-methyltransferase -2.44935
MRPL35 mitochondrial ribosomal protein L35 -2.44861
MSH2 mutS homolog 2 -2.44625
TOR3A torsin family 3, member A -2.44547
SMCO4 single-pass membrane protein with coiled-coil domains 4 -2.44425
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.43987
NME3 NME/NM23 nucleoside diphosphate kinase 3 -2.43751
OAZ2 ornithine decarboxylase antizyme 2 -2.43744
SPC25 SPC25, NDC80 kinetochore complex component -2.43544
QTRT1 queuine tRNA-ribosyltransferase 1 -2.43324
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -2.43262
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 -2.43167
CCS copper chaperone for superoxide dismutase -2.42659
OXA1L oxidase (cytochrome c) assembly 1-like -2.42638
DUT deoxyuridine triphosphatase -2.42354
DHRS4 dehydrogenase/reductase (SDR family) member 4 -2.42215
MGST2 microsomal glutathione S-transferase 2 -2.41906
AUH AU RNA binding protein/enoyl-CoA hydratase -2.41877
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.40732
PREB prolactin regulatory element binding -2.40579
QPRT quinolinate phosphoribosyltransferase -2.40046
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.40041
TOR1A torsin family 1, member A (torsin A) -2.3993
LYSET lysosomal enzyme trafficking factor -2.39687
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.39611
UXT ubiquitously-expressed, prefoldin-like chaperone -2.39359
SHCBP1 SHC SH2-domain binding protein 1 -2.3901
SH3D19 SH3 domain containing 19 -2.38397
SLIRP SRA stem-loop interacting RNA binding protein -2.37736
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.37594
ZMYM3 zinc finger, MYM-type 3 -2.36765
CHEK1 checkpoint kinase 1 -2.36761
MTTP microsomal triglyceride transfer protein -2.36734
FLOT2 flotillin 2 -2.3666
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.36565
AAMP angio-associated, migratory cell protein -2.36496
UROS uroporphyrinogen III synthase -2.36401
MRS2 MRS2 magnesium transporter -2.36097
FANCI Fanconi anemia, complementation group I -2.35967
BOLA1 bolA family member 1 -2.357
TMEM177 transmembrane protein 177 -2.35655
DSCC1 DNA replication and sister chromatid cohesion 1 -2.35539
MYH10 myosin, heavy chain 10, non-muscle -2.35537
POLR2F polymerase (RNA) II (DNA directed) polypeptide F -2.35486
TCTA T-cell leukemia translocation altered -2.35189
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -2.34925
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.34864
CPVL carboxypeptidase, vitellogenic-like -2.3476
SDF2L1 stromal cell-derived factor 2-like 1 -2.34685
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.34663
DEXI Dexi homolog (mouse) -2.34322
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -2.34193
NTHL1 nth endonuclease III-like 1 (E. coli) -2.33754
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.33477
CGREF1 cell growth regulator with EF-hand domain 1 -2.33163
TMPO thymopoietin -2.32776
CA9 carbonic anhydrase IX -2.3249
ENDOG endonuclease G -2.32297
MPV17 MpV17 mitochondrial inner membrane protein -2.32187
TFAM transcription factor A, mitochondrial -2.31629
ZNF106 zinc finger protein 106 -2.31404
ACYP1 acylphosphatase 1, erythrocyte (common) type -2.30983
NUP37 nucleoporin 37kDa -2.30372
FZD4 frizzled class receptor 4 -2.30202
BBS4 Bardet-Biedl syndrome 4 -2.29961
PEBP1 phosphatidylethanolamine binding protein 1 -2.2985
CROT carnitine O-octanoyltransferase -2.29847
SELENOT selenoprotein T -2.29798
MRPL46 mitochondrial ribosomal protein L46 -2.29735
NTS neurotensin -2.29666
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.29527
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase -2.29377
RBM15B RNA binding motif protein 15B -2.28991
BLM Bloom syndrome, RecQ helicase-like -2.28527
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -2.28266
GCH1 GTP cyclohydrolase 1 -2.27895
WRAP73 WD repeat containing, antisense to TP73 -2.27718
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.27705
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -2.27432
COMMD4 COMM domain containing 4 -2.27091
SYNGR2 synaptogyrin 2 -2.26876
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -2.26503
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -2.25692
EIF4A3 eukaryotic translation initiation factor 4A3 -2.25047
PRUNE1 prune exopolyphosphatase 1 -2.24827
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.24791
NUP210 nucleoporin 210kDa -2.24732
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.24627
TRMT61B tRNA methyltransferase 61B -2.24335
TBC1D10C TBC1 domain family, member 10C -2.24208
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -2.2419
TBC1D16 TBC1 domain family, member 16 -2.24043
ATP5IF1 ATP synthase inhibitory factor subunit 1 -2.23666
BCL7C B-cell CLL/lymphoma 7C -2.23631
PRC1 protein regulator of cytokinesis 1 -2.23494
APOM apolipoprotein M -2.23367
GOLGA8A golgin A8 family, member A -2.23054
MRPL4 mitochondrial ribosomal protein L4 -2.22542
KIF18A kinesin family member 18A -2.22429
MKRN2 makorin ring finger protein 2 -2.21968
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 -2.21614
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.21348
TTC38 tetratricopeptide repeat domain 38 -2.21077
MINPP1 multiple inositol-polyphosphate phosphatase 1 -2.20901
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -2.20899
UBAC1 UBA domain containing 1 -2.20814
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -2.20792
CDC6 cell division cycle 6 -2.20349
DCXR dicarbonyl/L-xylulose reductase -2.20293
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -2.19945
POLR2H polymerase (RNA) II (DNA directed) polypeptide H -2.19062
MRPS14 mitochondrial ribosomal protein S14 -2.1886
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -2.18812
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like -2.1876
MRPL34 mitochondrial ribosomal protein L34 -2.18386
PYCR3 pyrroline-5-carboxylate reductase 3 -2.18083
MRPL30 mitochondrial ribosomal protein L30 -2.17472
SATB1 SATB homeobox 1 -2.17202
LMNB1 lamin B1 -2.16754
TMCO1 transmembrane and coiled-coil domains 1 -2.1661
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -2.16324
CCNE1 cyclin E1 -2.1588
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -2.15815
ETV4 ets variant 4 -2.15794
ATRAID all-trans retinoic acid-induced differentiation factor -2.15746
COQ3 coenzyme Q3 methyltransferase -2.15471
ERCC6L excision repair cross-complementation group 6-like -2.15437
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.14905
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) -2.1473
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.14456
AHCY adenosylhomocysteinase -2.14405
ZNF200 zinc finger protein 200 -2.13949
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.13739
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -2.13653
CERS1 ceramide synthase 1 -2.13502
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -2.13237
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -2.13077
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 -2.12968
PRPF4 pre-mRNA processing factor 4 -2.12938
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.12876
INCENP inner centromere protein antigens 135/155kDa -2.12876
LYRM9 LYR motif containing 9 -2.12061
RABL6 RAB, member RAS oncogene family-like 6 -2.12024
ADPGK ADP-dependent glucokinase -2.1201
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.11578
LMAN2L lectin, mannose-binding 2-like -2.11135
PRMT3 protein arginine methyltransferase 3 -2.10992
TASOR transcription activation suppressor -2.10951
MOCS2 molybdenum cofactor synthesis 2 -2.10523
MRPL19 mitochondrial ribosomal protein L19 -2.10302
HMBS hydroxymethylbilane synthase -2.10226
CFI complement factor I -2.1021
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.10083
FXN frataxin -2.10017
GPC3 glypican 3 -2.09728
TMEM160 transmembrane protein 160 -2.0956
CEP55 centrosomal protein 55kDa -2.08982
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -2.08862
TRIM32 tripartite motif containing 32 -2.08832
STX10 syntaxin 10 -2.088
MDN1 MDN1, midasin homolog (yeast) -2.08771
NEK4 NIMA-related kinase 4 -2.08582
TEX10 testis expressed 10 -2.08571
ADD3 adducin 3 (gamma) -2.08147
SCAND1 SCAN domain containing 1 -2.08128
TMEM50B transmembrane protein 50B -2.07788
IGFLR1 IGF-like family receptor 1 -2.07724
ADISSP adipose secreted signaling protein -2.07485
MXD3 MAX dimerization protein 3 -2.07283
OCEL1 occludin/ELL domain containing 1 -2.07138
ASGR1 asialoglycoprotein receptor 1 -2.06695
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -2.06197
ZWILCH zwilch kinetochore protein -2.05927
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -2.0592
RFC3 replication factor C (activator 1) 3, 38kDa -2.05769
PEX11B peroxisomal biogenesis factor 11 beta -2.05736
WASHC3 WASH complex subunit 3 -2.05705
NCAPD3 non-SMC condensin II complex, subunit D3 -2.05697
FANCC Fanconi anemia, complementation group C -2.05683
RBM4B RNA binding motif protein 4B -2.05672
SORD sorbitol dehydrogenase -2.05641
FAM111A family with sequence similarity 111, member A -2.05617
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa -2.05532
STXBP2 syntaxin binding protein 2 -2.0539
TMEM106C transmembrane protein 106C -2.05317
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -2.04747
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.04601
CYFIP1 cytoplasmic FMR1 interacting protein 1 -2.04263
CHPT1 choline phosphotransferase 1 -2.04137
IVD isovaleryl-CoA dehydrogenase -2.04122
PARG poly (ADP-ribose) glycohydrolase -2.04096
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle -2.0346
NBEAL2 neurobeachin-like 2 -2.03138
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -2.02828
GCA grancalcin, EF-hand calcium binding protein -2.02705
SRSF2 serine/arginine-rich splicing factor 2 -2.02119
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 -2.01952
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -2.01786
CAMKMT calmodulin-lysine N-methyltransferase -2.0174
HNMT histamine N-methyltransferase -2.01445
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.0137
SCML2 sex comb on midleg-like 2 (Drosophila) -2.01321
ATP5PF ATP synthase peripheral stalk subunit F6 -2.01208
MCM3 minichromosome maintenance complex component 3 -2.0118
ECI2 enoyl-CoA delta isomerase 2 -2.01035
RAB33B RAB33B, member RAS oncogene family -2.00845
TKFC triokinase/FMN cyclase -2.00605
CRIPTO3 cripto, EGF-CFC family member 3 -2.00144
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -2.0009