CRCGN009_HEPG2_24H:H03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hexachlorophene 10.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

954 genes differentially expressed following the CRCGN009_HEPG2_24H:H03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
TXNRD1 thioredoxin reductase 1 9.70896
STX1A syntaxin 1A (brain) 9.31683
ABHD4 abhydrolase domain containing 4 8.57207
TIMP2 TIMP metallopeptidase inhibitor 2 8.46481
LCN2 lipocalin 2 7.70954
FOSL1 FOS-like antigen 1 7.36385
IGFBP3 insulin-like growth factor binding protein 3 7.22241
NR1H2 nuclear receptor subfamily 1, group H, member 2 7.09691
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 7.02309
INPP1 inositol polyphosphate-1-phosphatase 6.95509
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 6.88116
GFPT1 glutamine--fructose-6-phosphate transaminase 1 6.85968
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 6.7269
BACE2 beta-site APP-cleaving enzyme 2 6.59862
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 6.16306
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 5.97088
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 5.91838
NPC1 Niemann-Pick disease, type C1 5.88806
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 5.71515
SQSTM1 sequestosome 1 5.70127
CNPY3 canopy FGF signaling regulator 3 5.67961
BIRC2 baculoviral IAP repeat containing 2 5.47303
FHL2 four and a half LIM domains 2 5.38079
CYCS cytochrome c, somatic 5.34304
DDIT4 DNA-damage-inducible transcript 4 5.32959
CASC3 cancer susceptibility candidate 3 5.31662
SHB Src homology 2 domain containing adaptor protein B 5.21352
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.17807
AARS1 alanyl-tRNA synthetase 1 5.14785
PPARG peroxisome proliferator-activated receptor gamma 5.10092
SQOR sulfide quinone oxidoreductase 5.04573
MICALL1 MICAL-like 1 5.03949
CDK7 cyclin-dependent kinase 7 4.94753
CSNK1E casein kinase 1, epsilon 4.81313
GRB10 growth factor receptor-bound protein 10 4.78914
ADGRE5 adhesion G protein-coupled receptor E5 4.61619
NOTCH1 notch 1 4.54716
ZFP36 ZFP36 ring finger protein 4.54698
LSR lipolysis stimulated lipoprotein receptor 4.53642
GFOD1 glucose-fructose oxidoreductase domain containing 1 4.51994
PTK2 protein tyrosine kinase 2 4.47504
MYC v-myc avian myelocytomatosis viral oncogene homolog 4.38448
VAT1 vesicle amine transport 1 4.38066
TICAM1 toll-like receptor adaptor molecule 1 4.34612
IL4R interleukin 4 receptor 4.34269
TRIM13 tripartite motif containing 13 4.33268
GOLT1B golgi transport 1B 4.325
LRP10 low density lipoprotein receptor-related protein 10 4.31948
HLA-DMA major histocompatibility complex, class II, DM alpha 4.19191
MVP major vault protein 4.13783
UBQLN2 ubiquilin 2 4.13456
MBNL1 muscleblind-like splicing regulator 1 4.09929
EGR1 early growth response 1 4.08615
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 4.0374
PTPN12 protein tyrosine phosphatase, non-receptor type 12 3.9796
TRIB1 tribbles pseudokinase 1 3.88397
ALAS1 5'-aminolevulinate synthase 1 3.87937
CLIP4 CAP-GLY domain containing linker protein family, member 4 3.8696
TERF2IP telomeric repeat binding factor 2, interacting protein 3.82912
ADGRG1 adhesion G protein-coupled receptor G1 3.82526
NUP58 nucleoporin 58 3.8219
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.81652
DNM1L dynamin 1-like 3.81332
MAST2 microtubule associated serine/threonine kinase 2 3.78487
DUSP8 dual specificity phosphatase 8 3.77992
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 3.75766
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 3.75048
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 3.6908
FOXJ3 forkhead box J3 3.66061
TESK1 testis-specific kinase 1 3.65712
KDM5A lysine (K)-specific demethylase 5A 3.64735
KIFBP kinesin family binding protein 3.64536
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.60592
LOC128125814 uncharacterized LOC128125814 3.60005
KCMF1 potassium channel modulatory factor 1 3.59703
EPS8 epidermal growth factor receptor pathway substrate 8 3.54653
CCNA1 cyclin A1 3.53387
ZBTB35 zinc finger and BTB domain containing 35 3.53292
GARS1 glycyl-tRNA synthetase 1 3.50753
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 3.49578
OSGIN2 oxidative stress induced growth inhibitor family member 2 3.46703
TBC1D15 TBC1 domain family, member 15 3.45389
RAB21 RAB21, member RAS oncogene family 3.42036
MTERF3 mitochondrial transcription termination factor 3 3.39652
YIPF3 Yip1 domain family, member 3 3.37746
PTPRK protein tyrosine phosphatase, receptor type, K 3.34761
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.33475
GSTZ1 glutathione S-transferase zeta 1 3.33209
PMM2 phosphomannomutase 2 3.28581
JOSD1 Josephin domain containing 1 3.2757
YARS1 tyrosyl-tRNA synthetase 1 3.27496
H2BC21 H2B clustered histone 21 3.26298
CRISP2 cysteine-rich secretory protein 2 3.24964
IER3 immediate early response 3 3.238
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 3.23588
MBNL2 muscleblind-like splicing regulator 2 3.23046
TES testin LIM domain protein 3.22444
SMAD3 SMAD family member 3 3.2113
PRKCD protein kinase C, delta 3.20871
SARS1 seryl-tRNA synthetase 1 3.19513
GPC1 glypican 1 3.19266
EVL Enah/Vasp-like 3.18055
GTPBP2 GTP binding protein 2 3.17951
TENT4A terminal nucleotidyltransferase 4A 3.17929
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 3.17647
MAP7 microtubule-associated protein 7 3.17518
MMP7 matrix metallopeptidase 7 3.14989
SNX7 sorting nexin 7 3.14957
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 3.14592
MAGIX MAGI family member, X-linked 3.13711
ZYX zyxin 3.13663
BTG3 BTG family, member 3 3.13626
KDM6B lysine (K)-specific demethylase 6B 3.12462
E2F2 E2F transcription factor 2 3.1031
SLC35F2 solute carrier family 35, member F2 3.10178
CNTNAP3B contactin associated protein-like 3B 3.09044
IL37 interleukin 37 3.08082
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 3.06016
RPL39L ribosomal protein L39-like 3.05803
RGCC regulator of cell cycle 3.04678
STK10 serine/threonine kinase 10 3.04431
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 3.03376
SMNDC1 survival motor neuron domain containing 1 3.0135
PNKP polynucleotide kinase 3'-phosphatase 2.98985
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 2.98166
TP53BP2 tumor protein p53 binding protein 2 2.96223
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.96083
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.95008
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.93708
RGS2 regulator of G-protein signaling 2 2.92242
RAP1GAP RAP1 GTPase activating protein 2.91588
RAI14 retinoic acid induced 14 2.91362
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.90848
CLK3 CDC-like kinase 3 2.90676
PLK3 polo-like kinase 3 2.90126
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.89611
ANO1 anoctamin 1, calcium activated chloride channel 2.8876
ADRB2 adrenoceptor beta 2, surface 2.88243
CAMTA2 calmodulin binding transcription activator 2 2.8782
CTSL cathepsin L 2.87812
WDR13 WD repeat domain 13 2.86593
MYO1D myosin ID 2.8601
RIPK4 receptor-interacting serine-threonine kinase 4 2.85764
CLDN4 claudin 4 2.84536
ADAM2 ADAM metallopeptidase domain 2 2.81552
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.8142
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.80003
EIF3D eukaryotic translation initiation factor 3, subunit D 2.79852
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.77682
PXDC1 PX domain containing 1 2.77587
RAB3B RAB3B, member RAS oncogene family 2.76484
ANXA11 annexin A11 2.76012
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like 2.75384
NRBF2 nuclear receptor binding factor 2 2.75382
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 2.75154
PLSCR3 phospholipid scramblase 3 2.74975
KLHL4 kelch-like family member 4 2.7457
LIN37 lin-37 DREAM MuvB core complex component 2.74432
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.74202
DNASE2B deoxyribonuclease II beta 2.74082
HRK harakiri, BCL2 interacting protein 2.7363
ZFAND5 zinc finger, AN1-type domain 5 2.73128
PTPRF protein tyrosine phosphatase, receptor type, F 2.72482
H2BC17 H2B clustered histone 17 2.72332
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.72164
TEAD3 TEA domain family member 3 2.72026
PTPN14 protein tyrosine phosphatase, non-receptor type 14 2.71209
NR1D1 nuclear receptor subfamily 1, group D, member 1 2.71001
PCDHB11 protocadherin beta 11 2.70926
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 2.70668
ATF4 activating transcription factor 4 2.70667
IARS1 isoleucyl-tRNA synthetase 1 2.70252
NDEL1 nudE neurodevelopment protein 1-like 1 2.69875
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 2.68088
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 2.67369
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.67106
RALB v-ral simian leukemia viral oncogene homolog B 2.66448
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.6626
PLA2G2F phospholipase A2, group IIF 2.65602
SYNGR3 synaptogyrin 3 2.64848
MEST mesoderm specific transcript 2.64234
PHF1 PHD finger protein 1 2.64132
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.63704
HPSE heparanase 2.63134
EPHA3 EPH receptor A3 2.62269
STAP2 signal transducing adaptor family member 2 2.62042
CFLAR CASP8 and FADD-like apoptosis regulator 2.6191
MBTD1 mbt domain containing 1 2.60778
NCK1 NCK adaptor protein 1 2.6059
TJP1 tight junction protein 1 2.60456
NACA2 nascent polypeptide-associated complex alpha subunit 2 2.60064
NR1D2 nuclear receptor subfamily 1, group D, member 2 2.59746
PDE8A phosphodiesterase 8A 2.59258
N4BP3 NEDD4 binding protein 3 2.59083
DRD1 dopamine receptor D1 2.59048
CARS1 cysteinyl-tRNA synthetase 1 2.59035
PER1 period circadian clock 1 2.58399
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.58377
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.58196
KCTD13 potassium channel tetramerization domain containing 13 2.57858
TAPT1 transmembrane anterior posterior transformation 1 2.57737
UBE2H ubiquitin-conjugating enzyme E2H 2.57635
SNX13 sorting nexin 13 2.56916
RUSC2 RUN and SH3 domain containing 2 2.56229
USP15 ubiquitin specific peptidase 15 2.56133
GID4 GID complex subunit 4 2.54572
TBPL1 TBP-like 1 2.54296
GPR87 G protein-coupled receptor 87 2.54211
TBL2 transducin (beta)-like 2 2.53838
NT5E 5'-nucleotidase, ecto (CD73) 2.53177
TUT7 terminal uridylyl transferase 7 2.53155
IFRD1 interferon-related developmental regulator 1 2.52268
PRAF2 PRA1 domain family, member 2 2.52223
ATOSB atos homolog B 2.51954
LARP6 La ribonucleoprotein domain family, member 6 2.51388
BAG6 BCL2-associated athanogene 6 2.51381
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.51379
PPARD peroxisome proliferator-activated receptor delta 2.51236
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 2.50995
ATF6 activating transcription factor 6 2.50684
MCHR1 melanin-concentrating hormone receptor 1 2.49982
AADAC arylacetamide deacetylase 2.49536
YY1AP1 YY1 associated protein 1 2.48611
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.47799
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.47682
PTPN3 protein tyrosine phosphatase, non-receptor type 3 2.47317
ULK1 unc-51 like autophagy activating kinase 1 2.47308
SOCS2 suppressor of cytokine signaling 2 2.47284
RNF103 ring finger protein 103 2.47233
BEAN1 brain expressed, associated with NEDD4, 1 2.47117
TTLL4 tubulin tyrosine ligase-like family member 4 2.47001
FGF12 fibroblast growth factor 12 2.46207
YIPF4 Yip1 domain family, member 4 2.46196
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.46176
ANGPTL2 angiopoietin-like 2 2.46049
ATF3 activating transcription factor 3 2.46
MYH9 myosin, heavy chain 9, non-muscle 2.45923
POU1F1 POU class 1 homeobox 1 2.45704
MLNR motilin receptor 2.45631
DGKE diacylglycerol kinase, epsilon 64kDa 2.45458
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 2.45094
WARS1 tryptophanyl-tRNA synthetase 1 2.45003
PDGFA platelet-derived growth factor alpha polypeptide 2.44761
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.44726
TMEM156 transmembrane protein 156 2.44626
FABP2 fatty acid binding protein 2, intestinal 2.44024
KLHL21 kelch-like family member 21 2.43793
NPDC1 neural proliferation, differentiation and control, 1 2.43686
POU6F2 POU class 6 homeobox 2 2.4362
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 2.43607
DMTF1 cyclin D binding myb-like transcription factor 1 2.43555
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.43456
HABP2 hyaluronan binding protein 2 2.43294
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.43147
KRT86 keratin 86, type II 2.42603
IL2 interleukin 2 2.42574
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.42507
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa 2.42295
ADGB androglobin 2.42267
TIGD6 tigger transposable element derived 6 2.42111
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.4165
GADD45A growth arrest and DNA-damage-inducible, alpha 2.41634
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.41334
BYSL bystin-like 2.41155
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 2.40656
UPP1 uridine phosphorylase 1 2.4026
HABP4 hyaluronan binding protein 4 2.39874
PAPOLB poly(A) polymerase beta (testis specific) 2.39447
HBP1 HMG-box transcription factor 1 2.39176
ZNF585B zinc finger protein 585B 2.38998
VSIG2 V-set and immunoglobulin domain containing 2 2.3898
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 2.38683
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.38618
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.38376
YME1L1 YME1-like 1 ATPase 2.38341
KIAA0513 KIAA0513 2.3754
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.37519
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 2.37017
EIF4A2 eukaryotic translation initiation factor 4A2 2.3687
CLIP2 CAP-GLY domain containing linker protein 2 2.36509
TSPAN2 tetraspanin 2 2.36398
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 2.36291
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.36188
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.3606
TCP11 t-complex 11, testis-specific 2.36
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 2.3561
SERINC1 serine incorporator 1 2.35354
TEX12 testis expressed 12 2.35249
GIPC1 GIPC PDZ domain containing family, member 1 2.35224
ELF4 E74-like factor 4 (ets domain transcription factor) 2.34176
MAP7D1 MAP7 domain containing 1 2.34057
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 2.33604
PSG5 pregnancy specific beta-1-glycoprotein 5 2.33415
ARHGAP8 Rho GTPase activating protein 8 2.33335
NIBAN1 niban apoptosis regulator 1 2.33093
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.33023
MFSD6 major facilitator superfamily domain containing 6 2.32899
SUCO SUN domain containing ossification factor 2.32774
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 2.32723
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.32716
SCRT1 scratch family zinc finger 1 2.32696
H2BC6 H2B clustered histone 6 2.32671
EZR ezrin 2.32583
NCOA3 nuclear receptor coactivator 3 2.31978
CYB5R3 cytochrome b5 reductase 3 2.31459
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 2.31244
NGFR nerve growth factor receptor 2.30695
TMEM184B transmembrane protein 184B 2.30539
GDI1 GDP dissociation inhibitor 1 2.30198
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 2.30143
ZBTB7C zinc finger and BTB domain containing 7C 2.30019
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 2.29852
TRPM6 transient receptor potential cation channel, subfamily M, member 6 2.29759
LDHAL6B lactate dehydrogenase A-like 6B 2.29636
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.29568
KCTD9 potassium channel tetramerization domain containing 9 2.2953
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.29525
SRSF4 serine/arginine-rich splicing factor 4 2.29102
ZNF674 zinc finger protein 674 2.29007
VCY1B variable charge, Y-linked 1B 2.28937
FOXD1 forkhead box D1 2.28843
SEC14L1 SEC14-like 1 (S. cerevisiae) 2.28678
STON1-GTF2A1L STON1-GTF2A1L readthrough 2.28551
FOXN1 forkhead box N1 2.27885
JHY junctional cadherin complex regulator 2.27865
SPAG9 sperm associated antigen 9 2.27684
HDLBP high density lipoprotein binding protein 2.27446
EXOC6B exocyst complex component 6B 2.27288
NPVF neuropeptide VF precursor 2.27257
USP3 ubiquitin specific peptidase 3 2.27009
MED15 mediator complex subunit 15 2.26859
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 2.26735
GOLT1A golgi transport 1A 2.26731
PRSS8 protease, serine, 8 2.26422
BRWD1 bromodomain and WD repeat domain containing 1 2.26208
KIAA0408 KIAA0408 2.26054
WDR46 WD repeat domain 46 2.26026
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 2.25927
CAMTA1 calmodulin binding transcription activator 1 2.25758
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 2.2565
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 2.25597
TBC1D22B TBC1 domain family, member 22B 2.2547
ZBTB33 zinc finger and BTB domain containing 33 2.25416
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 2.25355
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.25102
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.24721
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.24712
SORBS3 sorbin and SH3 domain containing 3 2.24631
OMP olfactory marker protein 2.24004
CLTB clathrin, light chain B 2.23639
CD2AP CD2-associated protein 2.23251
IL11 interleukin 11 2.23012
ANKRD12 ankyrin repeat domain 12 2.22815
KDM3A lysine (K)-specific demethylase 3A 2.22808
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2 2.22426
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.22189
ZFAND3 zinc finger, AN1-type domain 3 2.22123
ITGAV integrin, alpha V 2.22101
RFX3 regulatory factor X, 3 (influences HLA class II expression) 2.22034
NCKAP1 NCK-associated protein 1 2.21992
ZBTB10 zinc finger and BTB domain containing 10 2.21962
CYTH2 cytohesin 2 2.2174
IFNA5 interferon, alpha 5 2.215
TSC22D1 TSC22 domain family, member 1 2.21391
ABHD11 abhydrolase domain containing 11 2.2134
EIF3L eukaryotic translation initiation factor 3, subunit L 2.20934
PURG purine-rich element binding protein G 2.20852
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.20583
ZNF80 zinc finger protein 80 2.20438
GCM2 glial cells missing homolog 2 (Drosophila) 2.20422
STAT5B signal transducer and activator of transcription 5B 2.20144
SRFBP1 serum response factor binding protein 1 2.19799
HOXB8 homeobox B8 2.19575
RAB9A RAB9A, member RAS oncogene family 2.19354
RSF1 remodeling and spacing factor 1 2.19285
TIMP1 TIMP metallopeptidase inhibitor 1 2.19194
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.19086
HCRTR1 hypocretin (orexin) receptor 1 2.19035
CFAP73 cilia and flagella associated protein 73 2.19
ZNF141 zinc finger protein 141 2.18996
IL36RN interleukin 36 receptor antagonist 2.18789
ATXN7 ataxin 7 2.17832
PLS1 plastin 1 2.17573
ZNF549 zinc finger protein 549 2.17486
ATXN3L ataxin 3-like 2.1746
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.17399
INHBE inhibin, beta E 2.1735
GLRA3 glycine receptor, alpha 3 2.173
FBXO7 F-box protein 7 2.17166
SMR3A submaxillary gland androgen regulated protein 3A 2.17153
MORC1 MORC family CW-type zinc finger 1 2.17146
CYSLTR1 cysteinyl leukotriene receptor 1 2.17099
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 2.17095
KLF7 Kruppel-like factor 7 (ubiquitous) 2.17008
PARP6 poly (ADP-ribose) polymerase family, member 6 2.16913
AGBL3 ATP/GTP binding protein-like 3 2.16692
SNX16 sorting nexin 16 2.1664
DOCK3 dedicator of cytokinesis 3 2.1664
CCDC144A coiled-coil domain containing 144A 2.16625
HID1 HID1 domain containing 2.16284
IMPG1 interphotoreceptor matrix proteoglycan 1 2.16266
MMUT methylmalonyl-CoA mutase 2.16218
CINP cyclin-dependent kinase 2 interacting protein 2.16207
UBQLN3 ubiquilin 3 2.15721
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 2.15649
BTG4 B-cell translocation gene 4 2.15431
MAN2A1 mannosidase, alpha, class 2A, member 1 2.15307
SREBF2 sterol regulatory element binding transcription factor 2 2.15305
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 2.15098
OR2J3 olfactory receptor, family 2, subfamily J, member 3 2.14678
UBR4 ubiquitin protein ligase E3 component n-recognin 4 2.14641
LCOR ligand dependent nuclear receptor corepressor 2.14551
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 2.14259
ZNF557 zinc finger protein 557 2.14102
SLC25A30 solute carrier family 25, member 30 2.13952
GORASP2 golgi reassembly stacking protein 2, 55kDa 2.13951
QPCTL glutaminyl-peptide cyclotransferase-like 2.13923
ZNF343 zinc finger protein 343 2.1386
DKK1 dickkopf WNT signaling pathway inhibitor 1 2.13785
MAP3K2 mitogen-activated protein kinase kinase kinase 2 2.13777
KLF9 Kruppel-like factor 9 2.137
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 2.13497
TEX10 testis expressed 10 2.13393
PEDS1 plasmanylethanolamine desaturase 1 2.13228
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 2.13099
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.13012
ARC activity-regulated cytoskeleton-associated protein 2.128
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 2.12522
PDZD8 PDZ domain containing 8 2.12414
AGO2 argonaute RISC catalytic component 2 2.12405
SPO11 SPO11 meiotic protein covalently bound to DSB 2.12255
SPATA1 spermatogenesis associated 1 2.12206
RIPK2 receptor-interacting serine-threonine kinase 2 2.12066
FOXD3 forkhead box D3 2.12048
CRYGB crystallin, gamma B 2.11845
FAM135A family with sequence similarity 135, member A 2.11735
TACR3 tachykinin receptor 3 2.11729
TAS2R9 taste receptor, type 2, member 9 2.11665
RGPD8 RANBP2-like and GRIP domain containing 8 2.11664
SOS2 son of sevenless homolog 2 (Drosophila) 2.1163
CFAP68 cilia and flagella associated protein 68 2.11618
TRPC6 transient receptor potential cation channel, subfamily C, member 6 2.11384
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 2.10531
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 2.10458
ACTN4 actinin, alpha 4 2.1032
FBXO22 F-box protein 22 2.10269
ZNF407 zinc finger protein 407 2.10181
GRAMD1C GRAM domain containing 1C 2.10108
DGKB diacylglycerol kinase, beta 90kDa 2.10076
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.0995
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 2.09642
LZTS3 leucine zipper, putative tumor suppressor family member 3 2.09548
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 2.09398
ESS2 ess-2 splicing factor homolog 2.09337
MAPK12 mitogen-activated protein kinase 12 2.09309
TMEM265 transmembrane protein 265 2.091
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 2.08948
UEVLD UEV and lactate/malate dehyrogenase domains 2.08776
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.08766
INVS inversin 2.0867
MMP13 matrix metallopeptidase 13 2.0862
PSG2 pregnancy specific beta-1-glycoprotein 2 2.08429
CNTN5 contactin 5 2.08328
GPR25 G protein-coupled receptor 25 2.08299
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.08128
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.07993
CCDC82 coiled-coil domain containing 82 2.07979
PELI1 pellino E3 ubiquitin protein ligase 1 2.07951
TSPAN15 tetraspanin 15 2.07869
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 2.07863
BRSK2 BR serine/threonine kinase 2 2.07854
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.07817
CCPG1 cell cycle progression 1 2.07675
VNN1 vanin 1 2.07575
SPRYD7 SPRY domain containing 7 2.07501
STRN4 striatin, calmodulin binding protein 4 2.07427
ARF4 ADP-ribosylation factor 4 2.0735
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.07264
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 2.07148
MNT MAX network transcriptional repressor 2.06874
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.06838
CLEC5A C-type lectin domain family 5, member A 2.06817
KXD1 KxDL motif containing 1 2.06677
GSC2 goosecoid homeobox 2 2.06571
CST1 cystatin SN 2.06568
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.0654
GCC2 GRIP and coiled-coil domain containing 2 2.06528
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 2.06506
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 2.06467
FCMR Fc fragment of IgM receptor 2.0645
JMJD1C jumonji domain containing 1C 2.06281
TBP TATA box binding protein 2.06213
GPKOW G patch domain and KOW motifs 2.0612
UIMC1 ubiquitin interaction motif containing 1 2.06092
CEP170B centrosomal protein 170B 2.06062
DNAH17 dynein, axonemal, heavy chain 17 2.05819
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 2.05793
CMKLR2 chemerin chemokine-like receptor 2 2.05755
BCL2L1 BCL2-like 1 2.0574
ZNF354A zinc finger protein 354A 2.05615
RFC2 replication factor C (activator 1) 2, 40kDa 2.05579
KITLG KIT ligand 2.05419
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.05298
C2CD2L C2CD2-like 2.05185
HIC1 hypermethylated in cancer 1 2.05183
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 2.05049
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.04908
RIN3 Ras and Rab interactor 3 2.04814
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 2.04802
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.04528
RAD21L1 RAD21-like 1 (S. pombe) 2.04516
XDH xanthine dehydrogenase 2.04446
NVL nuclear VCP-like 2.04397
RFPL1 ret finger protein-like 1 2.0421
EIF1B eukaryotic translation initiation factor 1B 2.04151
MYH4 myosin, heavy chain 4, skeletal muscle 2.04075
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.04065
BMP5 bone morphogenetic protein 5 2.03987
OCRL oculocerebrorenal syndrome of Lowe 2.03977
SPRED2 sprouty-related, EVH1 domain containing 2 2.03955
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.03859
TGFA transforming growth factor, alpha 2.03805
RAB27B RAB27B, member RAS oncogene family 2.03683
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 2.03679
CST8 cystatin 8 (cystatin-related epididymal specific) 2.03571
IFT54 intraflagellar transport 54 2.03413
RIOK3 RIO kinase 3 2.03383
BRD1 bromodomain containing 1 2.03172
RB1CC1 RB1-inducible coiled-coil 1 2.03123
VEZT vezatin, adherens junctions transmembrane protein 2.02997
FZD1 frizzled class receptor 1 2.02977
BIRC3 baculoviral IAP repeat containing 3 2.02969
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 2.02938
PSEN1 presenilin 1 2.02938
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.02886
KLF3 Kruppel-like factor 3 (basic) 2.02879
CIRSR corepressor of RBPJ and splicing regulator 2.02779
WBP4 WW domain binding protein 4 2.02749
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.02734
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 2.02727
MECR mitochondrial trans-2-enoyl-CoA reductase 2.02727
FEZF2 FEZ family zinc finger 2 2.02554
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 2.02516
RIPOR1 RHO family interacting cell polarization regulator 1 2.0238
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 2.02331
VGLL1 vestigial-like family member 1 2.02286
CYB5R2 cytochrome b5 reductase 2 2.02122
TRPC5 transient receptor potential cation channel, subfamily C, member 5 2.02076
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide 2.02034
PAQR5 progestin and adipoQ receptor family member V 2.01971
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 2.01918
IRGC immunity-related GTPase family, cinema 2.01615
UBAP1 ubiquitin associated protein 1 2.01575
PDPN podoplanin 2.01451
CASS4 Cas scaffolding protein family member 4 2.01347
DOP1B DOP1 leucine zipper like protein B 2.01215
ADAM29 ADAM metallopeptidase domain 29 2.01166
ALOXE3 arachidonate lipoxygenase 3 2.0113
NPHP1 nephronophthisis 1 (juvenile) 2.0111
SLC6A16 solute carrier family 6, member 16 2.01078
EXOC5 exocyst complex component 5 2.00998
CSRNP2 cysteine-serine-rich nuclear protein 2 2.00956
DCAF1 DDB1 and CUL4 associated factor 1 2.00923
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 2.00649
ITPRID2 ITPR interacting domain containing 2 2.0059
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.00583
GLRA1 glycine receptor, alpha 1 2.00469
MEF2A myocyte enhancer factor 2A 2.00451
NOL4 nucleolar protein 4 2.00434
RBMXL2 RNA binding motif protein, X-linked-like 2 2.00339
ZNF451 zinc finger protein 451 2.00262
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.00247
ANKRD7 ankyrin repeat domain 7 2.00116
TULP2 tubby like protein 2 2.00096
ZNF234 zinc finger protein 234 2.00073
TRIM23 tripartite motif containing 23 2.00017

decreased expression

Symbol Name Standardized Value
CD320 CD320 molecule -10.0
B4GAT1 beta-1,4-glucuronyltransferase 1 -10.0
PARP1 poly (ADP-ribose) polymerase 1 -9.90387
PSRC1 proline/serine-rich coiled-coil 1 -9.39435
BLCAP bladder cancer associated protein -8.72602
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -8.63509
STMN1 stathmin 1 -8.23925
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -7.98986
THAP11 THAP domain containing 11 -7.96022
TARBP1 TAR (HIV-1) RNA binding protein 1 -7.92917
HSPB1 heat shock 27kDa protein 1 -7.87245
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -7.78046
PCNA proliferating cell nuclear antigen -7.43513
PGAM4 phosphoglycerate mutase family member 4 -7.3841
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -7.1728
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -7.13667
CCNA2 cyclin A2 -7.12963
TCTN1 tectonic family member 1 -7.04196
ZNF274 zinc finger protein 274 -6.92959
PLK1 polo-like kinase 1 -6.89122
INTS3 integrator complex subunit 3 -6.83311
ADI1 acireductone dioxygenase 1 -6.79424
CCNB1 cyclin B1 -6.50857
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -6.46219
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -6.45471
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -6.23635
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -6.08114
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -6.03562
TOP2A topoisomerase (DNA) II alpha 170kDa -5.87336
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -5.74635
CDC20 cell division cycle 20 -5.72987
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -5.68598
GLOD4 glyoxalase domain containing 4 -5.68563
TMEM109 transmembrane protein 109 -5.6202
UBE2C ubiquitin-conjugating enzyme E2C -5.59465
GTF2A2 general transcription factor IIA, 2, 12kDa -5.58412
PXMP2 peroxisomal membrane protein 2, 22kDa -5.55753
HMGA2 high mobility group AT-hook 2 -5.50841
ISOC1 isochorismatase domain containing 1 -5.48899
UBE3C ubiquitin protein ligase E3C -5.29662
ZW10 zw10 kinetochore protein -5.26642
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -5.24291
POLR1A polymerase (RNA) I polypeptide A, 194kDa -5.16651
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -5.14057
COG7 component of oligomeric golgi complex 7 -5.09069
BIRC5 baculoviral IAP repeat containing 5 -5.08865
RUVBL1 RuvB-like AAA ATPase 1 -5.08393
NLRP2B NLR family pyrin domain containing 2B -5.0346
AMDHD2 amidohydrolase domain containing 2 -5.00815
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -4.94624
LBR lamin B receptor -4.91228
ZNF586 zinc finger protein 586 -4.86642
MRPL12 mitochondrial ribosomal protein L12 -4.82387
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.81799
MLEC malectin -4.76226
AURKB aurora kinase B -4.66914
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.5382
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -4.53591
NUP85 nucleoporin 85kDa -4.47009
NENF neudesin neurotrophic factor -4.36639
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -4.36548
CDK1 cyclin-dependent kinase 1 -4.31809
CBR1 carbonyl reductase 1 -4.27886
CRYZ crystallin, zeta (quinone reductase) -4.26018
ICAM3 intercellular adhesion molecule 3 -4.19434
CCNB2 cyclin B2 -4.18144
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -4.15482
LDHD lactate dehydrogenase D -4.1433
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.1383
TPM1 tropomyosin 1 (alpha) -4.07144
AKAP8 A kinase (PRKA) anchor protein 8 -4.06182
PRCP prolylcarboxypeptidase (angiotensinase C) -4.04914
PROS1 protein S (alpha) -4.0407
TFDP1 transcription factor Dp-1 -4.00826
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.97281
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -3.96513
CDK4 cyclin-dependent kinase 4 -3.92253
CCND3 cyclin D3 -3.90398
TSEN2 TSEN2 tRNA splicing endonuclease subunit -3.89973
MYCBP MYC binding protein -3.88409
LAGE3 L antigen family, member 3 -3.86493
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -3.77706
KIF4A kinesin family member 4A -3.72865
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -3.71963
MELK maternal embryonic leucine zipper kinase -3.70917
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.70636
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -3.70149
MCM10 minichromosome maintenance complex component 10 -3.6689
TMEM97 transmembrane protein 97 -3.66399
ALDOC aldolase C, fructose-bisphosphate -3.66132
GAA glucosidase, alpha; acid -3.62112
RNASE7 ribonuclease, RNase A family, 7 -3.60122
TLCD3A TLC domain containing 3A -3.59193
NFIL3 nuclear factor, interleukin 3 regulated -3.54441
HMOX1 heme oxygenase 1 -3.53097
CHEK2 checkpoint kinase 2 -3.49535
PAGR1 PAXIP1 associated glutamate-rich protein 1 -3.49067
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.47071
CENPX centromere protein X -3.4603
KANSL1 KAT8 regulatory NSL complex subunit 1 -3.4543
TMEM106C transmembrane protein 106C -3.43878
FABP5 fatty acid binding protein 5 (psoriasis-associated) -3.4329
C2CD5 C2 calcium-dependent domain containing 5 -3.42096
PEPD peptidase D -3.40989
NCAPG2 non-SMC condensin II complex, subunit G2 -3.36726
AURKA aurora kinase A -3.35322
STIMATE STIM activating enhancer -3.34176
LMNB1 lamin B1 -3.31586
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -3.31317
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -3.28526
CASP3 caspase 3, apoptosis-related cysteine peptidase -3.27745
RPA3 replication protein A3, 14kDa -3.26796
CCNF cyclin F -3.25193
PGM1 phosphoglucomutase 1 -3.24363
TMEM14A transmembrane protein 14A -3.22843
GSTM2 glutathione S-transferase mu 2 (muscle) -3.21984
HADH hydroxyacyl-CoA dehydrogenase -3.14463
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -3.1407
RBM14-RBM4 RBM14-RBM4 readthrough -3.13516
RPIA ribose 5-phosphate isomerase A -3.12421
TUBB6 tubulin, beta 6 class V -3.12091
SHMT1 serine hydroxymethyltransferase 1 (soluble) -3.10127
FAIM Fas apoptotic inhibitory molecule -3.09741
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -3.09277
CENPA centromere protein A -3.07939
TXLNA taxilin alpha -3.05571
TSPAN6 tetraspanin 6 -3.04007
ASF1B anti-silencing function 1B histone chaperone -3.00982
PCCB propionyl CoA carboxylase, beta polypeptide -3.0086
CSK c-src tyrosine kinase -2.99946
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.99516
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.98272
ZWINT ZW10 interacting kinetochore protein -2.97496
MRPL11 mitochondrial ribosomal protein L11 -2.9592
MSH6 mutS homolog 6 -2.94994
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.93928
TK1 thymidine kinase 1, soluble -2.91198
HYOU1 hypoxia up-regulated 1 -2.89383
TEDC2 tubulin epsilon and delta complex 2 -2.88256
OIP5 Opa interacting protein 5 -2.85682
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -2.84121
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.83499
SEPHS1 selenophosphate synthetase 1 -2.83348
WDR77 WD repeat domain 77 -2.82804
TM9SF3 transmembrane 9 superfamily member 3 -2.80836
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.78297
SCCPDH saccharopine dehydrogenase (putative) -2.78182
LOC124907782 dual specificity protein phosphatase 22 -2.78108
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.76858
PTTG1 pituitary tumor-transforming 1 -2.76717
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.7594
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.75213
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.74679
TBC1D10C TBC1 domain family, member 10C -2.74415
CDCA3 cell division cycle associated 3 -2.74374
FKBP3 FK506 binding protein 3, 25kDa -2.72958
LYPLA1 lysophospholipase I -2.72893
FZD4 frizzled class receptor 4 -2.71996
SNF8 SNF8, ESCRT-II complex subunit -2.71458
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.69491
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.69182
NME1 NME/NM23 nucleoside diphosphate kinase 1 -2.68878
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.6857
KIFC1 kinesin family member C1 -2.67987
DUT deoxyuridine triphosphatase -2.67902
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.67629
PDF peptide deformylase (mitochondrial) -2.66968
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.66933
DSG2 desmoglein 2 -2.65888
LYRM1 LYR motif containing 1 -2.65459
COA3 cytochrome c oxidase assembly factor 3 -2.65441
TMX1 thioredoxin-related transmembrane protein 1 -2.64066
GID8 GID complex subunit 8 -2.63351
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.62119
EXTL2 exostosin-like glycosyltransferase 2 -2.61769
ANAPC15 anaphase promoting complex subunit 15 -2.61763
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.61357
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.60974
RIOX1 ribosomal oxygenase 1 -2.60643
QTRT1 queuine tRNA-ribosyltransferase 1 -2.60552
HAT1 histone acetyltransferase 1 -2.59977
TRAPPC3 trafficking protein particle complex 3 -2.59676
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.58906
DERA deoxyribose-phosphate aldolase (putative) -2.57886
MRPL16 mitochondrial ribosomal protein L16 -2.56934
NUP62 nucleoporin 62kDa -2.56306
PRUNE1 prune exopolyphosphatase 1 -2.56292
CDCA8 cell division cycle associated 8 -2.55429
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -2.54829
HOXA5 homeobox A5 -2.54547
SCARB1 scavenger receptor class B, member 1 -2.5436
ABHD14A abhydrolase domain containing 14A -2.5419
TWF2 twinfilin actin binding protein 2 -2.53811
MAT2A methionine adenosyltransferase II, alpha -2.53652
GPS1 G protein pathway suppressor 1 -2.52711
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.52438
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.51941
UNC119B unc-119 homolog B (C. elegans) -2.51615
UBTF upstream binding transcription factor, RNA polymerase I -2.51363
LRRC61 leucine rich repeat containing 61 -2.50618
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -2.5032
CDK5 cyclin-dependent kinase 5 -2.50271
FEN1 flap structure-specific endonuclease 1 -2.501
HEATR1 HEAT repeat containing 1 -2.49951
TMEM9B TMEM9 domain family, member B -2.4926
TMCO1 transmembrane and coiled-coil domains 1 -2.4924
VAV3 vav 3 guanine nucleotide exchange factor -2.48975
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.48724
MRPL34 mitochondrial ribosomal protein L34 -2.48391
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.47404
NASP nuclear autoantigenic sperm protein (histone-binding) -2.46861
DEXI Dexi homolog (mouse) -2.4646
PALB2 partner and localizer of BRCA2 -2.46185
TFAM transcription factor A, mitochondrial -2.46049
SPPL2A signal peptide peptidase like 2A -2.45763
LSM12 LSM12 homolog (S. cerevisiae) -2.44992
CHEK1 checkpoint kinase 1 -2.44894
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.44792
ECH1 enoyl CoA hydratase 1, peroxisomal -2.44242
MRPS7 mitochondrial ribosomal protein S7 -2.4404
EIF4A3 eukaryotic translation initiation factor 4A3 -2.43403
SASH3 SAM and SH3 domain containing 3 -2.43136
MGST2 microsomal glutathione S-transferase 2 -2.42992
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.42672
CKS1B CDC28 protein kinase regulatory subunit 1B -2.4213
H2AX H2A.X variant histone -2.42116
ARF5 ADP-ribosylation factor 5 -2.40495
SCAND1 SCAN domain containing 1 -2.40362
CCNE1 cyclin E1 -2.39731
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.39628
SRSF9 serine/arginine-rich splicing factor 9 -2.38907
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -2.38738
METTL9 methyltransferase like 9 -2.38612
MRPL48 mitochondrial ribosomal protein L48 -2.38277
GYS1 glycogen synthase 1 (muscle) -2.38274
WNT5A wingless-type MMTV integration site family, member 5A -2.38119
NCAPD3 non-SMC condensin II complex, subunit D3 -2.37904
PFN1 profilin 1 -2.36795
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.36774
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.36037
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.35673
PRPF4 pre-mRNA processing factor 4 -2.35405
TATDN2 TatD DNase domain containing 2 -2.34686
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.3423
AGMAT agmatine ureohydrolase (agmatinase) -2.34163
ATP5MF ATP synthase membrane subunit f -2.34022
PLA2G15 phospholipase A2, group XV -2.33892
LMAN2L lectin, mannose-binding 2-like -2.33848
PEBP1 phosphatidylethanolamine binding protein 1 -2.33749
BMP4 bone morphogenetic protein 4 -2.33638
RPS4Y1 ribosomal protein S4, Y-linked 1 -2.33406
GEMIN6 gem (nuclear organelle) associated protein 6 -2.32579
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -2.32338
DCXR dicarbonyl/L-xylulose reductase -2.31909
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.31728
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.31628
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -2.31348
ITGB1BP1 integrin beta 1 binding protein 1 -2.31338
KIF11 kinesin family member 11 -2.30839
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -2.3029
CETN3 centrin, EF-hand protein, 3 -2.30137
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.30047
SRSF1 serine/arginine-rich splicing factor 1 -2.29852
FANCI Fanconi anemia, complementation group I -2.2964
PDIA4 protein disulfide isomerase family A, member 4 -2.29561
TCTN3 tectonic family member 3 -2.29465
COQ3 coenzyme Q3 methyltransferase -2.29247
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -2.29132
TRIP13 thyroid hormone receptor interactor 13 -2.29092
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.28314
HEBP1 heme binding protein 1 -2.27383
COMMD9 COMM domain containing 9 -2.2674
GALE UDP-galactose-4-epimerase -2.26665
GET1 guided entry of tail-anchored proteins factor 1 -2.26234
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -2.25142
TMEM50A transmembrane protein 50A -2.24922
BST2 bone marrow stromal cell antigen 2 -2.24655
BANF1 barrier to autointegration factor 1 -2.24409
SNX11 sorting nexin 11 -2.24166
OXA1L oxidase (cytochrome c) assembly 1-like -2.23313
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -2.23082
MYL9 myosin, light chain 9, regulatory -2.22625
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -2.22105
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.22093
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) -2.22041
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 -2.21692
MIS18A MIS18 kinetochore protein A -2.2169
TTC38 tetratricopeptide repeat domain 38 -2.20574
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.20328
ADISSP adipose secreted signaling protein -2.20242
CENPM centromere protein M -2.20094
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.19791
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.19685
PPP4C protein phosphatase 4, catalytic subunit -2.19667
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -2.18955
TEFM transcription elongation factor, mitochondrial -2.18699
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.18698
UNG uracil-DNA glycosylase -2.18204
ERH enhancer of rudimentary homolog (Drosophila) -2.17986
SLC61A1 solute carrier family 61 member 1 -2.17985
NRIP1 nuclear receptor interacting protein 1 -2.17903
CDKN3 cyclin-dependent kinase inhibitor 3 -2.17693
HTD2 hydroxyacyl-thioester dehydratase type 2 -2.17569
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.17482
TCTN2 tectonic family member 2 -2.17281
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.16573
PDIA6 protein disulfide isomerase family A, member 6 -2.16528
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.16291
TSPAN3 tetraspanin 3 -2.16249
PAQR4 progestin and adipoQ receptor family member IV -2.1621
HSPA14 heat shock 70kDa protein 14 -2.16189
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.16138
IGFLR1 IGF-like family receptor 1 -2.15915
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle -2.15703
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -2.15422
ASB13 ankyrin repeat and SOCS box containing 13 -2.15327
OCEL1 occludin/ELL domain containing 1 -2.15312
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.14834
ALG11 ALG11, alpha-1,2-mannosyltransferase -2.14768
PYCR3 pyrroline-5-carboxylate reductase 3 -2.14436
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.14159
NR1H3 nuclear receptor subfamily 1, group H, member 3 -2.13641
RBBP4 retinoblastoma binding protein 4 -2.13607
KHK ketohexokinase (fructokinase) -2.13364
PGRMC1 progesterone receptor membrane component 1 -2.13328
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.13064
TIPIN TIMELESS interacting protein -2.12689
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -2.12529
FGGY FGGY carbohydrate kinase domain containing -2.11895
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.11868
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.11156
NUP37 nucleoporin 37kDa -2.111
EMC9 ER membrane protein complex subunit 9 -2.10726
PHB1 prohibitin 1 -2.10705
PYCARD PYD and CARD domain containing -2.10393
QDPR quinoid dihydropteridine reductase -2.10129
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -2.1003
PARN poly(A)-specific ribonuclease -2.10003
DCK deoxycytidine kinase -2.09733
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.09514
PAAF1 proteasomal ATPase-associated factor 1 -2.09356
COG4 component of oligomeric golgi complex 4 -2.09027
MCM4 minichromosome maintenance complex component 4 -2.08483
KIF15 kinesin family member 15 -2.0806
TBC1D16 TBC1 domain family, member 16 -2.07632
MSRB2 methionine sulfoxide reductase B2 -2.07544
FASTKD3 FAST kinase domains 3 -2.074
TRAPPC4 trafficking protein particle complex 4 -2.07381
S100A4 S100 calcium binding protein A4 -2.07364
RWDD3 RWD domain containing 3 -2.07346
ERCC6L excision repair cross-complementation group 6-like -2.07245
CENPE centromere protein E, 312kDa -2.07202
DSCC1 DNA replication and sister chromatid cohesion 1 -2.0699
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.06673
TMPO thymopoietin -2.06633
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.06386
RRM2 ribonucleotide reductase M2 -2.05813
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.0551
C1S complement component 1, s subcomponent -2.05172
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.04795
KAT2A K(lysine) acetyltransferase 2A -2.04709
CTSC cathepsin C -2.04631
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.03506
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.03436
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.03291
IL6 interleukin 6 -2.03033
CNOT7 CCR4-NOT transcription complex, subunit 7 -2.02427
NDC1 NDC1 transmembrane nucleoporin -2.02264
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 -2.02054
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -2.01683
AUNIP aurora kinase A and ninein interacting protein -2.01654
MCUR1 mitochondrial calcium uniporter regulator 1 -2.01434
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -2.01224
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -2.01183
PRR7 proline rich 7 (synaptic) -2.00703
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.00653
DCTPP1 dCTP pyrophosphatase 1 -2.00294