CRCGN009_HEPG2_24H:H04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hexachlorophene 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

707 genes differentially expressed following the CRCGN009_HEPG2_24H:H04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INPP1 inositol polyphosphate-1-phosphatase 8.65114
TXNRD1 thioredoxin reductase 1 8.49883
TIMP2 TIMP metallopeptidase inhibitor 2 8.42464
TRIB3 tribbles pseudokinase 3 8.38305
STX1A syntaxin 1A (brain) 7.70454
ANO1 anoctamin 1, calcium activated chloride channel 7.54549
ZFP36 ZFP36 ring finger protein 6.96017
CNPY3 canopy FGF signaling regulator 3 6.91397
GFPT1 glutamine--fructose-6-phosphate transaminase 1 6.73677
FOSL1 FOS-like antigen 1 6.45308
IGFBP3 insulin-like growth factor binding protein 3 6.37951
KIFBP kinesin family binding protein 6.3567
CDPF1 cysteine-rich, DPF motif domain containing 1 6.33958
GFOD1 glucose-fructose oxidoreductase domain containing 1 6.31492
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 6.00692
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.90595
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 5.74284
NPC1 Niemann-Pick disease, type C1 5.66673
SQSTM1 sequestosome 1 5.54875
CHMP6 charged multivesicular body protein 6 5.47558
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 5.41898
LSR lipolysis stimulated lipoprotein receptor 5.41847
CASC3 cancer susceptibility candidate 3 5.35842
ABHD4 abhydrolase domain containing 4 5.21403
CYCS cytochrome c, somatic 5.17807
DDIT4 DNA-damage-inducible transcript 4 5.14184
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 5.12147
GRB10 growth factor receptor-bound protein 10 5.04693
IER3 immediate early response 3 4.97721
AARS1 alanyl-tRNA synthetase 1 4.97592
SHB Src homology 2 domain containing adaptor protein B 4.96565
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.91709
BIRC2 baculoviral IAP repeat containing 2 4.80362
UBQLN2 ubiquilin 2 4.77127
STIMATE STIM activating enhancer 4.76997
GOLT1B golgi transport 1B 4.68297
PPARG peroxisome proliferator-activated receptor gamma 4.68257
CDK7 cyclin-dependent kinase 7 4.66065
VAT1 vesicle amine transport 1 4.47314
EGR1 early growth response 1 4.40937
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 4.39574
CIAO3 cytosolic iron-sulfur assembly component 3 4.39241
MYC v-myc avian myelocytomatosis viral oncogene homolog 4.37982
CSNK1E casein kinase 1, epsilon 4.34545
MVP major vault protein 4.25705
IL4R interleukin 4 receptor 4.23916
MICALL1 MICAL-like 1 4.15835
BACE2 beta-site APP-cleaving enzyme 2 4.1544
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 4.06748
TICAM1 toll-like receptor adaptor molecule 1 4.02862
LRP10 low density lipoprotein receptor-related protein 10 4.01684
MBNL2 muscleblind-like splicing regulator 2 4.00587
TRIM13 tripartite motif containing 13 3.9967
RAB11FIP1 RAB11 family interacting protein 1 (class I) 3.94022
PTPN12 protein tyrosine phosphatase, non-receptor type 12 3.92446
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.84474
RFC2 replication factor C (activator 1) 2, 40kDa 3.79443
RGS2 regulator of G-protein signaling 2 3.76818
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.76494
TRIB1 tribbles pseudokinase 1 3.7633
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.75946
RAP1GAP RAP1 GTPase activating protein 3.68476
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 3.67109
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 3.65368
ALAS1 5'-aminolevulinate synthase 1 3.61061
TERF2IP telomeric repeat binding factor 2, interacting protein 3.60559
STAP2 signal transducing adaptor family member 2 3.5946
PTK2 protein tyrosine kinase 2 3.59344
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 3.59168
IFRD1 interferon-related developmental regulator 1 3.58524
NOTCH1 notch 1 3.50424
FHL2 four and a half LIM domains 2 3.50264
KLHL21 kelch-like family member 21 3.47337
FOXJ3 forkhead box J3 3.43647
DNM1L dynamin 1-like 3.43589
NANOS3 nanos homolog 3 (Drosophila) 3.41782
PCDHB11 protocadherin beta 11 3.40275
CAMTA2 calmodulin binding transcription activator 2 3.35971
SOCS2 suppressor of cytokine signaling 2 3.3392
MBNL1 muscleblind-like splicing regulator 1 3.3203
ZBTB35 zinc finger and BTB domain containing 35 3.30542
PNKP polynucleotide kinase 3'-phosphatase 3.29887
EPS8 epidermal growth factor receptor pathway substrate 8 3.28445
SQOR sulfide quinone oxidoreductase 3.28226
PRKCQ protein kinase C, theta 3.27857
PDE8A phosphodiesterase 8A 3.27403
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 3.27221
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 3.26659
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.25706
SOX4 SRY (sex determining region Y)-box 4 3.25566
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 3.24762
ZFAND1 zinc finger, AN1-type domain 1 3.2408
SARS1 seryl-tRNA synthetase 1 3.23622
ATF6 activating transcription factor 6 3.23612
H2BC21 H2B clustered histone 21 3.2238
GTPBP2 GTP binding protein 2 3.2212
LCN2 lipocalin 2 3.21771
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.21093
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.19863
TESK1 testis-specific kinase 1 3.1782
GARS1 glycyl-tRNA synthetase 1 3.12969
DUSP8 dual specificity phosphatase 8 3.12567
LOC128125814 uncharacterized LOC128125814 3.12454
PTPRK protein tyrosine phosphatase, receptor type, K 3.11364
ZYX zyxin 3.09463
ADGRG1 adhesion G protein-coupled receptor G1 3.07829
PRAF2 PRA1 domain family, member 2 3.07353
RIPK4 receptor-interacting serine-threonine kinase 4 3.07323
TNIP1 TNFAIP3 interacting protein 1 3.07029
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 3.05559
TP53BP2 tumor protein p53 binding protein 2 2.99075
VGLL4 vestigial-like family member 4 2.9903
RB1 retinoblastoma 1 2.98796
WDR13 WD repeat domain 13 2.97852
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 2.93973
SMAD3 SMAD family member 3 2.93795
NDEL1 nudE neurodevelopment protein 1-like 1 2.91928
PRKCD protein kinase C, delta 2.9162
NUP58 nucleoporin 58 2.90677
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.90247
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.90208
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.89275
RBM6 RNA binding motif protein 6 2.89155
JOSD1 Josephin domain containing 1 2.88361
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 2.87713
MAP7 microtubule-associated protein 7 2.86896
PDGFA platelet-derived growth factor alpha polypeptide 2.86629
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.86549
NIBAN1 niban apoptosis regulator 1 2.86384
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.84824
CYTH2 cytohesin 2 2.84325
CLCA4 chloride channel accessory 4 2.83235
CARS1 cysteinyl-tRNA synthetase 1 2.81864
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.81758
ATF3 activating transcription factor 3 2.80027
GNL1 guanine nucleotide binding protein-like 1 2.79537
EVL Enah/Vasp-like 2.79494
KDM6B lysine (K)-specific demethylase 6B 2.77799
UNC5B unc-5 homolog B (C. elegans) 2.77509
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.77379
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.76278
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.7583
KDM5A lysine (K)-specific demethylase 5A 2.75688
SNAI1 snail family zinc finger 1 2.74489
MAG myelin associated glycoprotein 2.72377
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.72134
PPARD peroxisome proliferator-activated receptor delta 2.70692
ZBTB10 zinc finger and BTB domain containing 10 2.6702
ATF4 activating transcription factor 4 2.66361
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.64559
DHRS3 dehydrogenase/reductase (SDR family) member 3 2.64532
ZFAND5 zinc finger, AN1-type domain 5 2.63218
MMP7 matrix metallopeptidase 7 2.6249
YIPF3 Yip1 domain family, member 3 2.62324
WIPI1 WD repeat domain, phosphoinositide interacting 1 2.61928
PXDC1 PX domain containing 1 2.59455
SYNGR3 synaptogyrin 3 2.59356
ANKRD11 ankyrin repeat domain 11 2.58507
MAST2 microtubule associated serine/threonine kinase 2 2.58309
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.57008
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.56857
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 2.56543
MYO1D myosin ID 2.56259
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.55097
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.54992
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.54907
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 2.54263
PYGB phosphorylase, glycogen; brain 2.53715
NARS1 asparaginyl-tRNA synthetase 1 2.53466
GRWD1 glutamate-rich WD repeat containing 1 2.53007
ST18 suppression of tumorigenicity 18, zinc finger 2.52234
MAP3K2 mitogen-activated protein kinase kinase kinase 2 2.51772
GOLGB1 golgin B1 2.51696
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 2.51407
RRAGA Ras-related GTP binding A 2.50008
MARS1 methionyl-tRNA synthetase 1 2.4951
FBXO7 F-box protein 7 2.48151
YARS1 tyrosyl-tRNA synthetase 1 2.47965
ATOSB atos homolog B 2.47858
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.47412
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 2.46435
RTCA RNA 3'-terminal phosphate cyclase 2.45998
TMEM184B transmembrane protein 184B 2.45819
STAT5B signal transducer and activator of transcription 5B 2.45575
ZNF343 zinc finger protein 343 2.45068
DUSP3 dual specificity phosphatase 3 2.4403
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.43802
UPP1 uridine phosphorylase 1 2.43757
MMUT methylmalonyl-CoA mutase 2.43319
CLIP2 CAP-GLY domain containing linker protein 2 2.42596
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.42589
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.4222
ZPR1 ZPR1 zinc finger 2.41888
KCTD9 potassium channel tetramerization domain containing 9 2.40487
GPX2 glutathione peroxidase 2 2.39953
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 2.39923
ITCH itchy E3 ubiquitin protein ligase 2.39357
RUSC2 RUN and SH3 domain containing 2 2.38955
YJU2B YJU2 splicing factor homolog B 2.38507
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.379
PLK3 polo-like kinase 3 2.36635
DUSP5 dual specificity phosphatase 5 2.36139
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 2.35997
YPEL5 yippee-like 5 (Drosophila) 2.35978
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.35928
OSBPL2 oxysterol binding protein-like 2 2.35764
WARS1 tryptophanyl-tRNA synthetase 1 2.35666
SMAGP small cell adhesion glycoprotein 2.35148
RIOK3 RIO kinase 3 2.34473
BYSL bystin-like 2.34212
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.33356
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 2.33299
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.33255
SERINC1 serine incorporator 1 2.33202
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.33169
GCLC glutamate-cysteine ligase, catalytic subunit 2.32723
ARL14 ADP-ribosylation factor-like 14 2.32611
IQCB1 IQ motif containing B1 2.32416
BMP3 bone morphogenetic protein 3 2.31788
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.31712
TSSC4 tumor suppressing subtransferable candidate 4 2.31355
CARD14 caspase recruitment domain family, member 14 2.31227
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.30703
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.30495
CLEC5A C-type lectin domain family 5, member A 2.29988
UBR2 ubiquitin protein ligase E3 component n-recognin 2 2.2988
GSDMB gasdermin B 2.29531
ARID4B AT rich interactive domain 4B (RBP1-like) 2.29519
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2.29164
LGALS9C lectin, galactoside-binding, soluble, 9C 2.28974
BEST1 bestrophin 1 2.28489
TES testin LIM domain protein 2.28171
REM1 RAS (RAD and GEM)-like GTP-binding 1 2.28142
EIF4A2 eukaryotic translation initiation factor 4A2 2.28087
PADI2 peptidyl arginine deiminase, type II 2.28071
LARP6 La ribonucleoprotein domain family, member 6 2.27894
NCOA3 nuclear receptor coactivator 3 2.26868
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.26788
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.26247
RAI14 retinoic acid induced 14 2.26001
SYNJ2 synaptojanin 2 2.25965
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.25792
CLTB clathrin, light chain B 2.25186
GADD45A growth arrest and DNA-damage-inducible, alpha 2.24783
ADORA2B adenosine A2b receptor 2.2447
MBTD1 mbt domain containing 1 2.2389
APOBR apolipoprotein B receptor 2.23638
THBD thrombomodulin 2.23296
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 2.23018
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.22601
GCC1 GRIP and coiled-coil domain containing 1 2.22202
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 2.22037
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.22033
KLF13 Kruppel-like factor 13 2.21886
CIRSR corepressor of RBPJ and splicing regulator 2.21762
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.21651
TLK2 tousled-like kinase 2 2.2145
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.20713
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 2.20676
EPHA2 EPH receptor A2 2.20557
MTCH1 mitochondrial carrier 1 2.20388
OSGIN1 oxidative stress induced growth inhibitor 1 2.20344
TJAP1 tight junction associated protein 1 (peripheral) 2.20278
LAD1 ladinin 1 2.20227
BTBD3 BTB (POZ) domain containing 3 2.2016
IER2 immediate early response 2 2.19843
KLRF1 killer cell lectin-like receptor subfamily F, member 1 2.1944
HSPG2 heparan sulfate proteoglycan 2 2.18826
DSG2 desmoglein 2 2.18689
RB1CC1 RB1-inducible coiled-coil 1 2.18382
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 2.18325
CAB39 calcium binding protein 39 2.18069
TRAPPC6A trafficking protein particle complex 6A 2.17992
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 2.17562
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 2.1691
EPRS1 glutamyl-prolyl-tRNA synthetase 1 2.16671
ETV6 ets variant 6 2.16666
LHCGR luteinizing hormone/choriogonadotropin receptor 2.16585
EHF ets homologous factor 2.16543
PFDN2 prefoldin subunit 2 2.15953
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 2.1549
PORCN porcupine homolog (Drosophila) 2.15388
KLF9 Kruppel-like factor 9 2.1526
IARS1 isoleucyl-tRNA synthetase 1 2.15135
GDI1 GDP dissociation inhibitor 1 2.15087
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 2.14332
KRT12 keratin 12, type I 2.14287
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.13944
GHITM growth hormone inducible transmembrane protein 2.1367
GPC1 glypican 1 2.13583
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.13417
NGRN neugrin, neurite outgrowth associated 2.13308
MYH9 myosin, heavy chain 9, non-muscle 2.13284
GIPC1 GIPC PDZ domain containing family, member 1 2.12882
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 2.12783
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 2.1276
ACTN4 actinin, alpha 4 2.12706
NR4A3 nuclear receptor subfamily 4, group A, member 3 2.12332
GPATCH8 G patch domain containing 8 2.12238
SNAI2 snail family zinc finger 2 2.12177
LPXN leupaxin 2.12046
MXI1 MAX interactor 1, dimerization protein 2.1201
GABARAPL1 GABA(A) receptor-associated protein like 1 2.11996
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.11649
KIAA0513 KIAA0513 2.11462
NPDC1 neural proliferation, differentiation and control, 1 2.11425
KLF3 Kruppel-like factor 3 (basic) 2.11026
ROPN1B rhophilin associated tail protein 1B 2.11023
ATG101 autophagy related 101 2.10361
BAG6 BCL2-associated athanogene 6 2.10253
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.10114
UNC13D unc-13 homolog D (C. elegans) 2.09761
EPS8L3 EPS8-like 3 2.09412
IGF2R insulin-like growth factor 2 receptor 2.09269
H2BC17 H2B clustered histone 17 2.088
RASA2 RAS p21 protein activator 2 2.08526
GOLT1A golgi transport 1A 2.08382
PUM3 pumilio RNA binding family member 3 2.08327
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.08174
NHLH1 nescient helix loop helix 1 2.07961
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.07881
MAN2A1 mannosidase, alpha, class 2A, member 1 2.07653
SPON2 spondin 2, extracellular matrix protein 2.07637
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 2.071
SDC1 syndecan 1 2.06839
RGCC regulator of cell cycle 2.06785
TBCC tubulin folding cofactor C 2.06738
RTN4 reticulon 4 2.06592
NCK1 NCK adaptor protein 1 2.06419
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.06403
DNM2 dynamin 2 2.06388
MYOF myoferlin 2.06379
MSI1 musashi RNA-binding protein 1 2.06156
MBTPS1 membrane-bound transcription factor peptidase, site 1 2.05785
SMNDC1 survival motor neuron domain containing 1 2.05674
TENT4A terminal nucleotidyltransferase 4A 2.05557
STX5 syntaxin 5 2.05017
TESPA1 thymocyte expressed, positive selection associated 1 2.0465
RNF11 ring finger protein 11 2.04345
CRYGB crystallin, gamma B 2.03678
NXPE4 neurexophilin and PC-esterase domain family, member 4 2.03533
IL2 interleukin 2 2.03285
RALB v-ral simian leukemia viral oncogene homolog B 2.0294
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 2.02642
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 2.02639
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.02093
MACO1 macoilin 1 2.01982
SH2D2A SH2 domain containing 2A 2.0171
ZFAND3 zinc finger, AN1-type domain 3 2.0145
MED8 mediator complex subunit 8 2.01083
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.00966
TDRD3 tudor domain containing 3 2.00806
GRM3 glutamate receptor, metabotropic 3 2.00519
TMEM156 transmembrane protein 156 2.00516
HSPA13 heat shock protein 70kDa family, member 13 2.0022

decreased expression

Symbol Name Standardized Value
CD320 CD320 molecule -10.0
B4GAT1 beta-1,4-glucuronyltransferase 1 -10.0
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -9.69688
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -9.50267
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -8.14131
PGAM4 phosphoglycerate mutase family member 4 -7.8352
CCNB2 cyclin B2 -7.44822
PARP1 poly (ADP-ribose) polymerase 1 -7.38363
HSPA1A heat shock 70kDa protein 1A -7.1052
HSPB1 heat shock 27kDa protein 1 -7.02522
STMN1 stathmin 1 -6.99295
ZNF274 zinc finger protein 274 -6.75687
NLRP2B NLR family pyrin domain containing 2B -6.54311
THAP11 THAP domain containing 11 -6.51839
BLCAP bladder cancer associated protein -6.16394
CCNA2 cyclin A2 -6.14951
MELK maternal embryonic leucine zipper kinase -6.09387
TMEM109 transmembrane protein 109 -6.04262
NUP85 nucleoporin 85kDa -5.94943
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -5.93911
GLOD4 glyoxalase domain containing 4 -5.7036
GTF2A2 general transcription factor IIA, 2, 12kDa -5.69614
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -5.55197
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -5.46426
TLR4 toll-like receptor 4 -5.42247
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -5.25591
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -5.21027
ISOC1 isochorismatase domain containing 1 -5.19216
HAT1 histone acetyltransferase 1 -5.18993
TOP2A topoisomerase (DNA) II alpha 170kDa -5.14936
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -5.11148
CDK1 cyclin-dependent kinase 1 -5.0252
RPIA ribose 5-phosphate isomerase A -4.98758
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -4.97421
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -4.96519
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -4.86531
CCDC86 coiled-coil domain containing 86 -4.82742
HMGA2 high mobility group AT-hook 2 -4.80852
POLR1A polymerase (RNA) I polypeptide A, 194kDa -4.70016
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.69475
PXMP2 peroxisomal membrane protein 2, 22kDa -4.54011
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.53524
PSRC1 proline/serine-rich coiled-coil 1 -4.51906
RNASE7 ribonuclease, RNase A family, 7 -4.50375
AURKB aurora kinase B -4.42266
BIRC5 baculoviral IAP repeat containing 5 -4.41803
LBR lamin B receptor -4.41402
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.33091
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -4.326
UBE3C ubiquitin protein ligase E3C -4.32424
RUVBL1 RuvB-like AAA ATPase 1 -4.30697
NFIL3 nuclear factor, interleukin 3 regulated -4.26132
CBR1 carbonyl reductase 1 -4.21688
ASF1B anti-silencing function 1B histone chaperone -4.19116
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -4.15682
CDC20 cell division cycle 20 -4.11969
PLK1 polo-like kinase 1 -4.10468
MRPS16 mitochondrial ribosomal protein S16 -4.08503
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -4.0636
WASHC4 WASH complex subunit 4 -4.04501
ADI1 acireductone dioxygenase 1 -4.03548
MLEC malectin -4.03063
MRPS7 mitochondrial ribosomal protein S7 -3.96576
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.94093
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -3.91738
PGM1 phosphoglucomutase 1 -3.89575
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.89558
NENF neudesin neurotrophic factor -3.89232
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -3.86268
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.78456
LOC124907782 dual specificity protein phosphatase 22 -3.7826
PCNA proliferating cell nuclear antigen -3.77159
NT5DC2 5'-nucleotidase domain containing 2 -3.76604
CDK4 cyclin-dependent kinase 4 -3.75643
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.74486
AKAP8 A kinase (PRKA) anchor protein 8 -3.73209
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.71788
MCM10 minichromosome maintenance complex component 10 -3.71642
TSEN2 TSEN2 tRNA splicing endonuclease subunit -3.68756
CRYZ crystallin, zeta (quinone reductase) -3.65913
TFDP1 transcription factor Dp-1 -3.63774
TCTN1 tectonic family member 1 -3.58564
DCK deoxycytidine kinase -3.58133
MRPL12 mitochondrial ribosomal protein L12 -3.57048
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -3.55385
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -3.54851
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -3.51347
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -3.4981
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.49526
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -3.49399
SCAND1 SCAN domain containing 1 -3.45482
AMDHD2 amidohydrolase domain containing 2 -3.4355
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.38942
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -3.374
LAGE3 L antigen family, member 3 -3.37025
KIF11 kinesin family member 11 -3.36955
MRPL11 mitochondrial ribosomal protein L11 -3.3362
PRCP prolylcarboxypeptidase (angiotensinase C) -3.31553
ZW10 zw10 kinetochore protein -3.30917
PEG10 paternally expressed 10 -3.29355
TXLNA taxilin alpha -3.28535
TK1 thymidine kinase 1, soluble -3.27955
CETN3 centrin, EF-hand protein, 3 -3.24864
COG7 component of oligomeric golgi complex 7 -3.23811
DERA deoxyribose-phosphate aldolase (putative) -3.23725
PCCB propionyl CoA carboxylase, beta polypeptide -3.20508
SRSF9 serine/arginine-rich splicing factor 9 -3.19356
ICAM3 intercellular adhesion molecule 3 -3.16746
PROS1 protein S (alpha) -3.16363
SKIC8 SKI8 subunit of superkiller complex -3.13713
NUP107 nucleoporin 107kDa -3.09472
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -3.08077
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -3.07542
HADH hydroxyacyl-CoA dehydrogenase -3.07527
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -3.06021
RECQL4 RecQ protein-like 4 -3.05946
TRAPPC4 trafficking protein particle complex 4 -3.05452
NPY neuropeptide Y -3.05328
DDB2 damage-specific DNA binding protein 2, 48kDa -3.05196
ATP5IF1 ATP synthase inhibitory factor subunit 1 -3.05005
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.04477
FEN1 flap structure-specific endonuclease 1 -3.04396
KANSL1 KAT8 regulatory NSL complex subunit 1 -3.03178
KIF14 kinesin family member 14 -3.00177
RPA3 replication protein A3, 14kDa -2.96584
FBXL12 F-box and leucine-rich repeat protein 12 -2.94148
VKORC1 vitamin K epoxide reductase complex, subunit 1 -2.939
FANCI Fanconi anemia, complementation group I -2.93482
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.91468
MRPL16 mitochondrial ribosomal protein L16 -2.90412
MYCBP MYC binding protein -2.89503
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.88918
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.86055
TATDN2 TatD DNase domain containing 2 -2.85399
TMEM50A transmembrane protein 50A -2.84462
NCAPG2 non-SMC condensin II complex, subunit G2 -2.83863
PEBP1 phosphatidylethanolamine binding protein 1 -2.81384
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.80057
CSK c-src tyrosine kinase -2.79068
ATP5MF ATP synthase membrane subunit f -2.78786
TIPIN TIMELESS interacting protein -2.78543
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.77217
RBM14-RBM4 RBM14-RBM4 readthrough -2.76878
ERCC6L excision repair cross-complementation group 6-like -2.7687
PEPD peptidase D -2.76679
NUP62 nucleoporin 62kDa -2.75824
DUT deoxyuridine triphosphatase -2.75084
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.74807
GNAS GNAS complex locus -2.74544
NPC2 Niemann-Pick disease, type C2 -2.74276
HMOX1 heme oxygenase 1 -2.7393
MGST2 microsomal glutathione S-transferase 2 -2.72883
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.72036
MTCH2 mitochondrial carrier 2 -2.70884
CENPS-CORT CENPS-CORT readthrough -2.70077
KIF15 kinesin family member 15 -2.6969
TLCD3A TLC domain containing 3A -2.69305
PARG poly (ADP-ribose) glycohydrolase -2.68088
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.67097
MSH6 mutS homolog 6 -2.65422
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.65126
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.65087
ARF5 ADP-ribosylation factor 5 -2.63934
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.63248
CDC25B cell division cycle 25B -2.63166
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.61501
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.60782
CDCA8 cell division cycle associated 8 -2.60743
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.60209
MTARC1 mitochondrial amidoxime reducing component 1 -2.60168
CCNB1 cyclin B1 -2.59702
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') -2.59511
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.58524
ACYP1 acylphosphatase 1, erythrocyte (common) type -2.58298
FAM111A family with sequence similarity 111, member A -2.57429
BST2 bone marrow stromal cell antigen 2 -2.57134
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.56867
ZWINT ZW10 interacting kinetochore protein -2.56087
CDCA3 cell division cycle associated 3 -2.56029
UNC119B unc-119 homolog B (C. elegans) -2.55156
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.54585
XPO1 exportin 1 -2.54516
FKBP3 FK506 binding protein 3, 25kDa -2.53826
OIP5 Opa interacting protein 5 -2.52259
CENPA centromere protein A -2.51998
GEMIN6 gem (nuclear organelle) associated protein 6 -2.51385
TMEM106C transmembrane protein 106C -2.51222
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -2.50317
HOXA5 homeobox A5 -2.50149
VAV3 vav 3 guanine nucleotide exchange factor -2.50104
KIFC1 kinesin family member C1 -2.49752
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.49305
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.49016
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -2.48175
SNRPF small nuclear ribonucleoprotein polypeptide F -2.47517
ACAA1 acetyl-CoA acyltransferase 1 -2.46854
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.46744
UBL5 ubiquitin-like 5 -2.46496
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.46296
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.45067
MPC2 mitochondrial pyruvate carrier 2 -2.4497
HSPA14 heat shock 70kDa protein 14 -2.44782
RMI1 RecQ mediated genome instability 1 -2.44262
MRPL34 mitochondrial ribosomal protein L34 -2.43725
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.43233
TSPAN6 tetraspanin 6 -2.43148
THOP1 thimet oligopeptidase 1 -2.42878
TRAPPC3 trafficking protein particle complex 3 -2.42483
KHK ketohexokinase (fructokinase) -2.4171
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.41645
SNRPG small nuclear ribonucleoprotein polypeptide G -2.41566
TRIP13 thyroid hormone receptor interactor 13 -2.41421
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.41174
CCDC85B coiled-coil domain containing 85B -2.40934
C2CD5 C2 calcium-dependent domain containing 5 -2.40143
PLA2G15 phospholipase A2, group XV -2.39695
FZD4 frizzled class receptor 4 -2.386
MAT2A methionine adenosyltransferase II, alpha -2.38356
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.38344
EXOSC9 exosome component 9 -2.38174
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.37862
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.37725
ZDHHC6 zinc finger, DHHC-type containing 6 -2.37685
PDF peptide deformylase (mitochondrial) -2.37498
HMG20A high mobility group 20A -2.37462
MYH10 myosin, heavy chain 10, non-muscle -2.37351
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.37302
SEPHS1 selenophosphate synthetase 1 -2.3694
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -2.36742
RBX1 ring-box 1, E3 ubiquitin protein ligase -2.36528
NCAPD3 non-SMC condensin II complex, subunit D3 -2.36277
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.36096
HMGB2 high mobility group box 2 -2.35392
CCNF cyclin F -2.35005
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -2.3429
ZWILCH zwilch kinetochore protein -2.34102
LYRM1 LYR motif containing 1 -2.34018
CCNO cyclin O -2.33636
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -2.33572
SAC3D1 SAC3 domain containing 1 -2.33013
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa -2.32526
ENDOG endonuclease G -2.32368
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 -2.31828
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.31295
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -2.31128
PGRMC1 progesterone receptor membrane component 1 -2.31091
TUBB6 tubulin, beta 6 class V -2.29916
SPDL1 spindle apparatus coiled-coil protein 1 -2.29354
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.29233
ANAPC15 anaphase promoting complex subunit 15 -2.28186
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -2.27748
PPP4C protein phosphatase 4, catalytic subunit -2.27715
RPS27L ribosomal protein S27-like -2.27023
TEDC2 tubulin epsilon and delta complex 2 -2.2624
MIS18A MIS18 kinetochore protein A -2.25975
SLC35B1 solute carrier family 35, member B1 -2.25799
UBE2C ubiquitin-conjugating enzyme E2C -2.24597
SPPL2A signal peptide peptidase like 2A -2.24244
ABI3BP ABI family, member 3 (NESH) binding protein -2.24114
PRPF4 pre-mRNA processing factor 4 -2.23513
TFAM transcription factor A, mitochondrial -2.23258
NCAPH non-SMC condensin I complex, subunit H -2.23234
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -2.22534
DSCC1 DNA replication and sister chromatid cohesion 1 -2.22454
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.22111
SLIRP SRA stem-loop interacting RNA binding protein -2.22042
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.21297
AURKA aurora kinase A -2.21269
RPL26L1 ribosomal protein L26-like 1 -2.21164
CCDC51 coiled-coil domain containing 51 -2.21137
FIBP fibroblast growth factor (acidic) intracellular binding protein -2.20146
KIF4A kinesin family member 4A -2.19883
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 -2.1975
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.19615
SNF8 SNF8, ESCRT-II complex subunit -2.19562
MRPL19 mitochondrial ribosomal protein L19 -2.19475
ACOT9 acyl-CoA thioesterase 9 -2.1935
NASP nuclear autoantigenic sperm protein (histone-binding) -2.18994
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.18659
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.18375
DYNLL1 dynein, light chain, LC8-type 1 -2.18243
PRDX4 peroxiredoxin 4 -2.17753
CCND3 cyclin D3 -2.17239
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.17149
ATP5MJ ATP synthase membrane subunit j -2.17117
HMGB3 high mobility group box 3 -2.1696
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.15925
ERH enhancer of rudimentary homolog (Drosophila) -2.15632
ABHD14A abhydrolase domain containing 14A -2.15294
ATP5PD ATP synthase peripheral stalk subunit d -2.15245
PDIA6 protein disulfide isomerase family A, member 6 -2.15129
UNG uracil-DNA glycosylase -2.14856
CHAD chondroadherin -2.14489
MRPL23 mitochondrial ribosomal protein L23 -2.14369
DNAAF2 dynein, axonemal, assembly factor 2 -2.14334
SPAG5 sperm associated antigen 5 -2.1424
SNX1 sorting nexin 1 -2.14103
CBR4 carbonyl reductase 4 -2.14025
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.13794
UBE2N ubiquitin-conjugating enzyme E2N -2.13708
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.13551
SORD sorbitol dehydrogenase -2.1202
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.1174
CDKN3 cyclin-dependent kinase inhibitor 3 -2.1154
TMEM14A transmembrane protein 14A -2.11132
PTTG1 pituitary tumor-transforming 1 -2.11088
IVD isovaleryl-CoA dehydrogenase -2.11021
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.10953
PDZK1 PDZ domain containing 1 -2.10853
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -2.10789
EED embryonic ectoderm development -2.10355
HNMT histamine N-methyltransferase -2.10228
CDC7 cell division cycle 7 -2.10173
BBS1 Bardet-Biedl syndrome 1 -2.10073
PRR7 proline rich 7 (synaptic) -2.09827
NR1H3 nuclear receptor subfamily 1, group H, member 3 -2.09722
CCNE1 cyclin E1 -2.09429
TSPAN3 tetraspanin 3 -2.08928
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -2.08866
TMPO thymopoietin -2.08767
MRPL35 mitochondrial ribosomal protein L35 -2.08702
EDC4 enhancer of mRNA decapping 4 -2.08697
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -2.0854
SH3D19 SH3 domain containing 19 -2.08498
COL9A1 collagen, type IX, alpha 1 -2.08344
ACP2 acid phosphatase 2, lysosomal -2.08254
DHFR dihydrofolate reductase -2.07943
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.07539
BANF1 barrier to autointegration factor 1 -2.07022
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -2.06635
RPLP1 ribosomal protein, large, P1 -2.06525
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -2.06133
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.05057
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -2.0505
ORC6 origin recognition complex, subunit 6 -2.04991
PPY pancreatic polypeptide -2.04944
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -2.04934
WASHC3 WASH complex subunit 3 -2.04534
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -2.04408
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.04291
TROAP trophinin associated protein -2.04106
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.03706
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G -2.03422
ZBED1 zinc finger, BED-type containing 1 -2.03104
ELAVL1 ELAV like RNA binding protein 1 -2.02744
FOXM1 forkhead box M1 -2.02421
COX7B cytochrome c oxidase subunit VIIb -2.01835
SASH3 SAM and SH3 domain containing 3 -2.01585
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 -2.01524
ENO3 enolase 3 (beta, muscle) -2.0034
ARHGAP19 Rho GTPase activating protein 19 -2.00148
PRUNE1 prune exopolyphosphatase 1 -2.00037