CRCGN009_HEPG2_24H:H08 Gene Set
Genes
48 genes differentially expressed following the CRCGN009_HEPG2_24H:H08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
6.24128
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
6.2384
|
|
PLS1
|
plastin 1
|
3.76514
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.72155
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
3.64343
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.60776
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.59856
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.5364
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.50846
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.42167
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.15576
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.06706
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.74812
|
|
MCOLN1
|
mucolipin 1
|
2.74242
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.74211
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.70589
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.69911
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.68534
|
|
MBNL1
|
muscleblind-like splicing regulator 1
|
2.6153
|
|
UBQLN2
|
ubiquilin 2
|
2.60755
|
|
NOTCH1
|
notch 1
|
2.51762
|
|
MOK
|
MOK protein kinase
|
2.48609
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.4504
|
|
TEX10
|
testis expressed 10
|
2.40379
|
|
SFTPB
|
surfactant protein B
|
2.10267
|
|
EVL
|
Enah/Vasp-like
|
2.08127
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
2.07803
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
UBE3C
|
ubiquitin protein ligase E3C
|
-7.07664
|
|
COG2
|
component of oligomeric golgi complex 2
|
-3.80714
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.71509
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.6445
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.48834
|
|
CCNB2
|
cyclin B2
|
-3.29657
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.79168
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.77059
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.69722
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.56341
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.54793
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-2.54704
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.4913
|
|
LDHD
|
lactate dehydrogenase D
|
-2.46263
|
|
TCERG1
|
transcription elongation regulator 1
|
-2.38387
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.27608
|
|
SNX11
|
sorting nexin 11
|
-2.15204
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.12149
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.07738
|
|
NVL
|
nuclear VCP-like
|
-2.05734
|
|
FUT1
|
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
|
-2.00736
|
