CRCGN009_HEPG2_24H:H10 Gene Set
Genes
45 genes differentially expressed following the CRCGN009_HEPG2_24H:H10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
7.04497
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.42933
|
|
CBR3
|
carbonyl reductase 3
|
4.33338
|
|
CCNF
|
cyclin F
|
4.15516
|
|
NOTCH1
|
notch 1
|
4.04027
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.03194
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.95434
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.84619
|
|
EVL
|
Enah/Vasp-like
|
3.74549
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.22376
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.97071
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.85066
|
|
CHN1
|
chimerin 1
|
2.7828
|
|
VGLL4
|
vestigial-like family member 4
|
2.66459
|
|
KIF5C
|
kinesin family member 5C
|
2.5675
|
|
E2F2
|
E2F transcription factor 2
|
2.43712
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.36126
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.34794
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.33392
|
|
NUDT13
|
nudix (nucleoside diphosphate linked moiety X)-type motif 13
|
2.30505
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.30046
|
|
ECD
|
ecdysoneless homolog (Drosophila)
|
2.27518
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.04789
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-5.54805
|
|
TLR4
|
toll-like receptor 4
|
-5.27074
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.20948
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.08591
|
|
LDHD
|
lactate dehydrogenase D
|
-3.05982
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.90751
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.84757
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.77447
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.77161
|
|
CDC20
|
cell division cycle 20
|
-2.71696
|
|
THAP11
|
THAP domain containing 11
|
-2.63121
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.58403
|
|
FBXO7
|
F-box protein 7
|
-2.57044
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.35031
|
|
CCNB2
|
cyclin B2
|
-2.34182
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.32716
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.30971
|
|
CDC25B
|
cell division cycle 25B
|
-2.30646
|
|
CCNB1
|
cyclin B1
|
-2.25397
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.19973
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.14403
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.0779
|
