| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | diphenhydramine 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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63 genes differentially expressed following the CRCGN009_HEPG2_24H:H12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SQOR | sulfide quinone oxidoreductase | 6.95941 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 5.26385 |
| CCL2 | chemokine (C-C motif) ligand 2 | 5.19875 |
| SCRN1 | secernin 1 | 5.14847 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.44811 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 4.38501 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.1749 |
| NOTCH1 | notch 1 | 4.12921 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.11129 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.91872 |
| JADE2 | jade family PHD finger 2 | 3.75521 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 3.26349 |
| SFTPB | surfactant protein B | 3.26046 |
| MAP7 | microtubule-associated protein 7 | 3.08605 |
| MMP1 | matrix metallopeptidase 1 | 3.04898 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.01314 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.93921 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.8943 |
| TBC1D10C | TBC1 domain family, member 10C | 2.85759 |
| IDE | insulin-degrading enzyme | 2.58428 |
| VGLL4 | vestigial-like family member 4 | 2.48349 |
| LOC122526780 | uncharacterized LOC122526780 | 2.48192 |
| MEST | mesoderm specific transcript | 2.47064 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.4091 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 2.19879 |
| KLHL9 | kelch-like family member 9 | 2.15263 |
| WDR7 | WD repeat domain 7 | 2.14261 |
| STX17 | syntaxin 17 | 2.13316 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.12932 |
| E2F2 | E2F transcription factor 2 | 2.10423 |
| SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 2.08417 |
| AMBP | alpha-1-microglobulin/bikunin precursor | 2.03312 |
| CEP57 | centrosomal protein 57kDa | 2.0082 |
| GPATCH8 | G patch domain containing 8 | 2.00629 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FASTKD5 | FAST kinase domains 5 | -7.29313 |
| PCNA | proliferating cell nuclear antigen | -7.14925 |
| LDHD | lactate dehydrogenase D | -5.75419 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.54953 |
| ZNF586 | zinc finger protein 586 | -4.42125 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.1416 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.03404 |
| CCNB1 | cyclin B1 | -3.76831 |
| THAP11 | THAP domain containing 11 | -3.29696 |
| WASHC4 | WASH complex subunit 4 | -3.08749 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -2.97896 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.85942 |
| TRIB3 | tribbles pseudokinase 3 | -2.82877 |
| CERS6 | ceramide synthase 6 | -2.5817 |
| GTPBP8 | GTP-binding protein 8 (putative) | -2.43046 |
| TBCB | tubulin folding cofactor B | -2.367 |
| HYOU1 | hypoxia up-regulated 1 | -2.34787 |
| FTSJ3 | FtsJ homolog 3 (E. coli) | -2.30783 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -2.28623 |
| TLR4 | toll-like receptor 4 | -2.17585 |
| GPATCH1 | G patch domain containing 1 | -2.12662 |
| LIN37 | lin-37 DREAM MuvB core complex component | -2.12503 |
| KEAP1 | kelch-like ECH-associated protein 1 | -2.11094 |
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | -2.09855 |
| NGRN | neugrin, neurite outgrowth associated | -2.094 |
| GALE | UDP-galactose-4-epimerase | -2.0395 |
| RBM42 | RNA binding motif protein 42 | -2.03541 |
| CERT1 | ceramide transporter 1 | -2.00106 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -2.00078 |
