| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triphenylphosphine oxide 20.12 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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61 genes differentially expressed following the CRCGN009_HEPG2_24H:H13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 6.01991 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 5.85418 |
| CHMP6 | charged multivesicular body protein 6 | 5.35788 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.22182 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.98993 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.86341 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.67612 |
| CHN1 | chimerin 1 | 4.45708 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.3693 |
| MYLK | myosin light chain kinase | 4.26326 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.25359 |
| RXYLT1 | ribitol xylosyltransferase 1 | 4.25329 |
| SCRN1 | secernin 1 | 4.20256 |
| ADAM10 | ADAM metallopeptidase domain 10 | 3.96765 |
| KLHL21 | kelch-like family member 21 | 3.86681 |
| ALDOC | aldolase C, fructose-bisphosphate | 3.38853 |
| CCNA1 | cyclin A1 | 3.36846 |
| LCN2 | lipocalin 2 | 3.17005 |
| ATP11B | ATPase, class VI, type 11B | 2.85074 |
| MEST | mesoderm specific transcript | 2.77695 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.51295 |
| HEBP1 | heme binding protein 1 | 2.41477 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | 2.39682 |
| NOSIP | nitric oxide synthase interacting protein | 2.37228 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 2.29855 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.28934 |
| BBX | bobby sox homolog (Drosophila) | 2.24336 |
| MCRS1 | microspherule protein 1 | 2.20093 |
| PFKL | phosphofructokinase, liver | 2.18269 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.17798 |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) | 2.05489 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCDC86 | coiled-coil domain containing 86 | -5.22325 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.10467 |
| LDHD | lactate dehydrogenase D | -5.10088 |
| FASTKD5 | FAST kinase domains 5 | -4.76322 |
| TLR4 | toll-like receptor 4 | -4.12151 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -4.11738 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.7157 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -3.2623 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.25294 |
| ZNF586 | zinc finger protein 586 | -3.19216 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.18783 |
| PCNA | proliferating cell nuclear antigen | -3.18769 |
| YME1L1 | YME1-like 1 ATPase | -3.17569 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.10808 |
| CD320 | CD320 molecule | -3.08988 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.07121 |
| CCNB1 | cyclin B1 | -3.04232 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.01762 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.83795 |
| TCERG1 | transcription elongation regulator 1 | -2.54556 |
| RNF167 | ring finger protein 167 | -2.35816 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.23066 |
| CSK | c-src tyrosine kinase | -2.22681 |
| STX4 | syntaxin 4 | -2.19383 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.17481 |
| TOR1A | torsin family 1, member A (torsin A) | -2.16299 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.13086 |
| ZW10 | zw10 kinetochore protein | -2.04901 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.0206 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.00814 |
