CRCGN009_HEPG2_24H:H14 Gene Set
Genes
46 genes differentially expressed following the CRCGN009_HEPG2_24H:H14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
7.64088
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
5.35384
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
4.17291
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
4.11709
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.93537
|
|
RPL39L
|
ribosomal protein L39-like
|
3.91542
|
|
UBQLN2
|
ubiquilin 2
|
3.8072
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.78827
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.66689
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.39503
|
|
CHN1
|
chimerin 1
|
3.35789
|
|
GATA2
|
GATA binding protein 2
|
2.92565
|
|
PTK2
|
protein tyrosine kinase 2
|
2.66055
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.59399
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.58852
|
|
DHDDS
|
dehydrodolichyl diphosphate synthase
|
2.38675
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.31949
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.27791
|
|
CHEK2
|
checkpoint kinase 2
|
2.23341
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.07173
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.02802
|
|
RAB3IL1
|
RAB3A interacting protein (rabin3)-like 1
|
2.01842
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB1
|
cyclin B1
|
-7.50896
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-5.06069
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.61064
|
|
GNAS
|
GNAS complex locus
|
-4.27364
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.9891
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.90031
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.88451
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.70537
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.38462
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.32433
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.18531
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.11147
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.03104
|
|
PGAM4
|
phosphoglycerate mutase family member 4
|
-2.91564
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.84945
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.84832
|
|
LDHD
|
lactate dehydrogenase D
|
-2.57516
|
|
PNOC
|
prepronociceptin
|
-2.33409
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.12537
|
|
H4C7
|
H4 clustered histone 7
|
-2.11609
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.06363
|
|
ZNG1A
|
Zn regulated GTPase metalloprotein activator 1A
|
-2.04522
|
|
FOXD3
|
forkhead box D3
|
-2.0228
|
|
USP27X
|
ubiquitin specific peptidase 27, X-linked
|
-2.01101
|
