| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triphenylphosphine oxide 2.52 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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56 genes differentially expressed following the CRCGN009_HEPG2_24H:H16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 7.02749 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.78694 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 6.70294 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 6.49395 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.18092 |
| BZW2 | basic leucine zipper and W2 domains 2 | 4.11209 |
| LCN2 | lipocalin 2 | 4.05364 |
| GPATCH8 | G patch domain containing 8 | 4.00382 |
| SQOR | sulfide quinone oxidoreductase | 3.82967 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.8117 |
| CHEK2 | checkpoint kinase 2 | 3.58651 |
| TATDN2 | TatD DNase domain containing 2 | 3.54441 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 3.37418 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 3.36295 |
| CBR3 | carbonyl reductase 3 | 2.98548 |
| MYLK | myosin light chain kinase | 2.94734 |
| PLSCR1 | phospholipid scramblase 1 | 2.83603 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.77933 |
| ATP11B | ATPase, class VI, type 11B | 2.57381 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.49194 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.30105 |
| CCNF | cyclin F | 2.27771 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.21136 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.16704 |
| MRPL42 | mitochondrial ribosomal protein L42 | 2.14589 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.13479 |
| ANO10 | anoctamin 10 | 2.09707 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | 2.00014 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.80886 |
| PCNA | proliferating cell nuclear antigen | -5.62713 |
| TLR4 | toll-like receptor 4 | -5.35325 |
| CCNB2 | cyclin B2 | -5.16201 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -3.51036 |
| CDC20 | cell division cycle 20 | -3.21956 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.16703 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.1418 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.09314 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.06652 |
| FASTKD5 | FAST kinase domains 5 | -2.9202 |
| NISCH | nischarin | -2.84605 |
| PEG10 | paternally expressed 10 | -2.83847 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.71144 |
| RBM15B | RNA binding motif protein 15B | -2.62511 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.59546 |
| GOLT1B | golgi transport 1B | -2.58016 |
| CAB39 | calcium binding protein 39 | -2.53306 |
| STON1-GTF2A1L | STON1-GTF2A1L readthrough | -2.28711 |
| CA10 | carbonic anhydrase X | -2.18554 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.18084 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.17061 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.16238 |
| AKAP4 | A kinase (PRKA) anchor protein 4 | -2.15883 |
| PRPF4 | pre-mRNA processing factor 4 | -2.14572 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa | -2.05279 |
| DDX4 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 | -2.02319 |
| GK2 | glycerol kinase 2 | -2.01524 |
