CRCGN009_HEPG2_24H:H17 Gene Set
Genes
56 genes differentially expressed following the CRCGN009_HEPG2_24H:H17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.10898
|
|
UBQLN2
|
ubiquilin 2
|
3.7346
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.72508
|
|
MYLK
|
myosin light chain kinase
|
3.70717
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.41717
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.38409
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.30707
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.17691
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.17572
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
3.03436
|
|
EPHB2
|
EPH receptor B2
|
3.00357
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.99191
|
|
NOTCH1
|
notch 1
|
2.94356
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.81382
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.67514
|
|
GATA2
|
GATA binding protein 2
|
2.5923
|
|
EPN2
|
epsin 2
|
2.56247
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.42375
|
|
KIF20A
|
kinesin family member 20A
|
2.41749
|
|
SFTPB
|
surfactant protein B
|
2.40537
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.24187
|
|
NUCB2
|
nucleobindin 2
|
2.23085
|
|
POLR3D
|
polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
|
2.22342
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.18095
|
|
GATA3
|
GATA binding protein 3
|
2.14374
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.09204
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.08716
|
|
PARP3
|
poly (ADP-ribose) polymerase family, member 3
|
2.02341
|
|
MAP7
|
microtubule-associated protein 7
|
2.01443
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.33326
|
|
CCNB2
|
cyclin B2
|
-5.53142
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.21926
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-4.0252
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.71678
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.48805
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.48376
|
|
PEG10
|
paternally expressed 10
|
-3.47239
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.46024
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.38121
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.30035
|
|
FHL2
|
four and a half LIM domains 2
|
-3.24891
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.1553
|
|
LDHD
|
lactate dehydrogenase D
|
-3.13171
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.05334
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.05103
|
|
HYOU1
|
hypoxia up-regulated 1
|
-3.04323
|
|
CDC20
|
cell division cycle 20
|
-3.01293
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.83216
|
|
NUP93
|
nucleoporin 93kDa
|
-2.79629
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.72179
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.66384
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.6331
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.41468
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.39176
|
|
EGF
|
epidermal growth factor
|
-2.19118
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.05661
|
