CRCGN009_HEPG2_24H:H18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description triphenylphosphine oxide 0.63 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN009_HEPG2_24H:H18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FCHO1 FCH domain only 1 5.3163
GPER1 G protein-coupled estrogen receptor 1 4.29354
MOK MOK protein kinase 3.99162
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.75244
NOTCH1 notch 1 3.48313
ABHD4 abhydrolase domain containing 4 3.2904
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.2122
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.62639
MAP7 microtubule-associated protein 7 2.61386
HOXA10 homeobox A10 2.58023
KIFBP kinesin family binding protein 2.54549
DIPK1A divergent protein kinase domain 1A 2.49952
TIAM1 T-cell lymphoma invasion and metastasis 1 2.4488
PLSCR1 phospholipid scramblase 1 2.38425
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.08279
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.08176
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 2.01423

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -6.41619
OXA1L oxidase (cytochrome c) assembly 1-like -6.35723
NGRN neugrin, neurite outgrowth associated -6.20736
NRIP1 nuclear receptor interacting protein 1 -4.89562
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.1942
LDHD lactate dehydrogenase D -3.50181
ZDHHC6 zinc finger, DHHC-type containing 6 -3.0993
CAB39 calcium binding protein 39 -2.81688
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.72731
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.71319
PCNA proliferating cell nuclear antigen -2.37502
TLCD3A TLC domain containing 3A -2.35336
TM9SF3 transmembrane 9 superfamily member 3 -2.26624
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.20032
PEG10 paternally expressed 10 -2.14659
ZNF586 zinc finger protein 586 -2.11099
LOC124907782 dual specificity protein phosphatase 22 -2.0664