CRCGN009_HEPG2_24H:H20 Gene Set
Genes
54 genes differentially expressed following the CRCGN009_HEPG2_24H:H20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
6.53461
|
|
UBQLN2
|
ubiquilin 2
|
5.17703
|
|
SLC75A1
|
solute carrier family 75 member 1
|
4.52385
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.36679
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.94876
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.85732
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.83878
|
|
PRR15L
|
proline rich 15-like
|
3.6477
|
|
STIMATE
|
STIM activating enhancer
|
3.56097
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.44309
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.34326
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.31606
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.29227
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.24247
|
|
LCN2
|
lipocalin 2
|
3.2359
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.21586
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.9798
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.9109
|
|
MEST
|
mesoderm specific transcript
|
2.87619
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.76755
|
|
SMAD3
|
SMAD family member 3
|
2.46574
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.32101
|
|
MAPKAPK2
|
mitogen-activated protein kinase-activated protein kinase 2
|
2.23384
|
|
CYB561
|
cytochrome b561
|
2.21884
|
|
PTEN
|
phosphatase and tensin homolog
|
2.03031
|
|
IFT22
|
intraflagellar transport 22
|
2.00777
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-10.0
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-5.45286
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-5.31315
|
|
LDHD
|
lactate dehydrogenase D
|
-4.82373
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.35327
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.88056
|
|
RNF167
|
ring finger protein 167
|
-3.69322
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.26619
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.12437
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.08654
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.99296
|
|
GOLT1B
|
golgi transport 1B
|
-2.98051
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.97122
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.94741
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.72774
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.64061
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.57121
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.55829
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
-2.53842
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.49125
|
|
GNAS
|
GNAS complex locus
|
-2.4627
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.39771
|
|
TCTN1
|
tectonic family member 1
|
-2.35687
|
|
STK25
|
serine/threonine kinase 25
|
-2.30811
|
|
SCAND1
|
SCAN domain containing 1
|
-2.27964
|
|
AURKB
|
aurora kinase B
|
-2.11947
|
|
CD320
|
CD320 molecule
|
-2.07847
|
|
RNF25
|
ring finger protein 25
|
-2.02358
|
