| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tegafur 5.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN009_HEPG2_24H:H21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 5.04914 |
| PLSCR1 | phospholipid scramblase 1 | 5.03233 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.77172 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.67005 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.51019 |
| LCN2 | lipocalin 2 | 4.02004 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 4.01182 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.83428 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.82299 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 3.30426 |
| EVL | Enah/Vasp-like | 3.2877 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 2.85033 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.72679 |
| SFTPB | surfactant protein B | 2.64784 |
| NOSIP | nitric oxide synthase interacting protein | 2.43408 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 2.40471 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 2.3735 |
| FBXO34 | F-box protein 34 | 2.35182 |
| TAC4 | tachykinin 4 (hemokinin) | 2.29454 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) | 2.24328 |
| LYSET | lysosomal enzyme trafficking factor | 2.18493 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 2.15898 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.15756 |
| E2F2 | E2F transcription factor 2 | 2.15126 |
| OSBPL9 | oxysterol binding protein-like 9 | 2.10197 |
| TASP1 | taspase, threonine aspartase, 1 | 2.08207 |
| MCC | mutated in colorectal cancers | 2.07921 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 2.04056 |
| CETN3 | centrin, EF-hand protein, 3 | 2.01224 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADI1 | acireductone dioxygenase 1 | -7.5132 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -6.05287 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.33423 |
| PLK1 | polo-like kinase 1 | -5.17095 |
| TRIB3 | tribbles pseudokinase 3 | -4.96113 |
| GOLT1B | golgi transport 1B | -4.6132 |
| TLR4 | toll-like receptor 4 | -2.96133 |
| MTFR1 | mitochondrial fission regulator 1 | -2.86659 |
| XPO7 | exportin 7 | -2.74313 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.60859 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.60791 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.56686 |
| SNX11 | sorting nexin 11 | -2.55631 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.53834 |
| NVL | nuclear VCP-like | -2.50845 |
| FAIM | Fas apoptotic inhibitory molecule | -2.48959 |
| NUP93 | nucleoporin 93kDa | -2.42158 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.31433 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.25504 |
| CIDEB | cell death-inducing DFFA-like effector b | -2.17229 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 | -2.14581 |
| RBM34 | RNA binding motif protein 34 | -2.11567 |
| CD37 | CD37 molecule | -2.09355 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.05931 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.05752 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | -2.03338 |
