CRCGN009_HEPG2_24H:H23 Gene Set
Genes
48 genes differentially expressed following the CRCGN009_HEPG2_24H:H23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AMDHD2
|
amidohydrolase domain containing 2
|
10.0
|
|
SFTPB
|
surfactant protein B
|
5.65451
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
5.20599
|
|
MYLK
|
myosin light chain kinase
|
4.45765
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.40193
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.39391
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.92541
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.51007
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
3.13993
|
|
TEX10
|
testis expressed 10
|
2.9976
|
|
CYCS
|
cytochrome c, somatic
|
2.87387
|
|
SCRN1
|
secernin 1
|
2.70707
|
|
PMM2
|
phosphomannomutase 2
|
2.46725
|
|
JADE2
|
jade family PHD finger 2
|
2.46082
|
|
GPATCH8
|
G patch domain containing 8
|
2.42895
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.34796
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.18371
|
|
TBC1D31
|
TBC1 domain family, member 31
|
2.14628
|
|
TOP6BL
|
TOP6B like initiator of meiotic double strand breaks
|
2.14323
|
|
NHP2
|
NHP2 ribonucleoprotein
|
2.00607
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-9.0303
|
|
CDC20
|
cell division cycle 20
|
-8.92054
|
|
FASTKD5
|
FAST kinase domains 5
|
-5.1029
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.04236
|
|
THAP11
|
THAP domain containing 11
|
-4.74213
|
|
DNM1L
|
dynamin 1-like
|
-4.47634
|
|
TLR4
|
toll-like receptor 4
|
-4.39925
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.2611
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-4.16211
|
|
ZNF586
|
zinc finger protein 586
|
-4.08169
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-4.08136
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.04449
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.54003
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.23071
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-3.06222
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.78742
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.77949
|
|
RCOR3
|
REST corepressor 3
|
-2.48347
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.45444
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.43529
|
|
WASHC4
|
WASH complex subunit 4
|
-2.40266
|
|
HDAC4
|
histone deacetylase 4
|
-2.1487
|
|
RIOK3
|
RIO kinase 3
|
-2.13777
|
|
LRIG2
|
leucine-rich repeats and immunoglobulin-like domains 2
|
-2.13731
|
|
MUTYH
|
mutY homolog
|
-2.05893
|
|
ZNF14
|
zinc finger protein 14
|
-2.04896
|
|
HNF4G
|
hepatocyte nuclear factor 4, gamma
|
-2.04555
|
|
RLF
|
rearranged L-myc fusion
|
-2.03863
|
