CRCGN009_HEPG2_24H:I05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description disodium 4-amino-3-((e)-{4'-[(e)-(2,4-diaminophenyl)diazenyl][1,1'-biphenyl]-4-yl}diazenyl)-5-hydroxy-6-[(e)-phenyldiazenyl]-2,7-naphthalenedisulfonate 1.28 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

40 genes differentially expressed following the CRCGN009_HEPG2_24H:I05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.92935
CCDC92 coiled-coil domain containing 92 4.90126
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.65815
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.51123
MOK MOK protein kinase 4.3916
E2F2 E2F transcription factor 2 4.25967
HOXA10 homeobox A10 4.02285
CHMP6 charged multivesicular body protein 6 3.9366
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.88136
GSTZ1 glutathione S-transferase zeta 1 3.74881
SNAP25 synaptosomal-associated protein, 25kDa 3.54537
PEX11A peroxisomal biogenesis factor 11 alpha 3.17399
GPER1 G protein-coupled estrogen receptor 1 3.16518
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.16267
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.93661
SFTPB surfactant protein B 2.81327
H2BC12 H2B clustered histone 12 2.41677
NUP133 nucleoporin 133kDa 2.36262
PMM2 phosphomannomutase 2 2.34752
CDC73 cell division cycle 73 2.34504
LPAR2 lysophosphatidic acid receptor 2 2.30835
EPHA3 EPH receptor A3 2.17821
BMP4 bone morphogenetic protein 4 2.13289

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -9.16827
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -5.09451
GOLT1B golgi transport 1B -5.04043
TUBB6 tubulin, beta 6 class V -4.67709
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.61274
CCNB2 cyclin B2 -4.56916
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -4.43343
TRIB3 tribbles pseudokinase 3 -4.39723
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -4.07246
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.31872
CSK c-src tyrosine kinase -2.91781
OXA1L oxidase (cytochrome c) assembly 1-like -2.9134
EXT1 exostosin glycosyltransferase 1 -2.65681
ZNF586 zinc finger protein 586 -2.41442
TCERG1 transcription elongation regulator 1 -2.40834
TLCD3A TLC domain containing 3A -2.17779
PILRB paired immunoglobin-like type 2 receptor beta -2.0309