CRCGN009_HEPG2_24H:I14 Gene Set
Genes
55 genes differentially expressed following the CRCGN009_HEPG2_24H:I14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
7.09888
|
|
STIMATE
|
STIM activating enhancer
|
5.06267
|
|
LCN2
|
lipocalin 2
|
5.0
|
|
NOTCH1
|
notch 1
|
4.93282
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.8889
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.79145
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.17034
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.12607
|
|
E2F2
|
E2F transcription factor 2
|
3.95302
|
|
PRKCH
|
protein kinase C, eta
|
3.81253
|
|
CDC45
|
cell division cycle 45
|
3.46256
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
3.43039
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.42912
|
|
PLS1
|
plastin 1
|
3.27859
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.21106
|
|
CYCS
|
cytochrome c, somatic
|
3.1236
|
|
CCNF
|
cyclin F
|
2.81873
|
|
ECH1
|
enoyl CoA hydratase 1, peroxisomal
|
2.76707
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.64018
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.52922
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.526
|
|
DNM1
|
dynamin 1
|
2.30167
|
|
SFTPB
|
surfactant protein B
|
2.29809
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
2.2208
|
|
WDR7
|
WD repeat domain 7
|
2.1606
|
|
FAR2
|
fatty acyl CoA reductase 2
|
2.1596
|
|
RBKS
|
ribokinase
|
2.12536
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
2.11683
|
|
NCOA4
|
nuclear receptor coactivator 4
|
2.11425
|
|
JADE2
|
jade family PHD finger 2
|
2.10875
|
|
ENC1
|
ectodermal-neural cortex 1 (with BTB domain)
|
2.08639
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.01088
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-7.20226
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.18969
|
|
CCNB2
|
cyclin B2
|
-5.02782
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.90989
|
|
CSK
|
c-src tyrosine kinase
|
-4.8136
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
-4.75073
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-4.55219
|
|
LDHD
|
lactate dehydrogenase D
|
-4.07022
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.99512
|
|
ZNF586
|
zinc finger protein 586
|
-3.8818
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.81423
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.67262
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.06154
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.95248
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.87891
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.82732
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.7253
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.57174
|
|
LRRC41
|
leucine rich repeat containing 41
|
-2.32506
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.30425
|
|
DUSP5
|
dual specificity phosphatase 5
|
-2.26036
|
|
PEG10
|
paternally expressed 10
|
-2.04731
|
|
TOM1L2
|
target of myb1-like 2 (chicken)
|
-2.03394
|
