CRCGN009_HEPG2_24H:I19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-(2-bromo-2-ethylbutanoyl)urea 20.24 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

520 genes differentially expressed following the CRCGN009_HEPG2_24H:I19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
C2CD2 C2 calcium-dependent domain containing 2 10.0
CCL2 chemokine (C-C motif) ligand 2 7.14341
MAP7 microtubule-associated protein 7 6.81478
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 6.76539
FCHO1 FCH domain only 1 6.38483
BACE2 beta-site APP-cleaving enzyme 2 6.25709
PRKCH protein kinase C, eta 6.03302
RPL39L ribosomal protein L39-like 5.9329
ADGRE5 adhesion G protein-coupled receptor E5 5.86027
E2F2 E2F transcription factor 2 5.57555
HOXA10 homeobox A10 5.57256
CCDC85B coiled-coil domain containing 85B 5.42847
CBR3 carbonyl reductase 3 5.36758
PRAF2 PRA1 domain family, member 2 5.30597
PRKX protein kinase, X-linked 5.09207
GATA3 GATA binding protein 3 5.06519
GSTZ1 glutathione S-transferase zeta 1 5.03402
MAMLD1 mastermind-like domain containing 1 5.03092
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 5.00597
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.93128
LCN2 lipocalin 2 4.75398
ADRB2 adrenoceptor beta 2, surface 4.73915
UBQLN2 ubiquilin 2 4.72631
PEX11A peroxisomal biogenesis factor 11 alpha 4.64223
EPHB2 EPH receptor B2 4.57097
MNAT1 MNAT CDK-activating kinase assembly factor 1 4.56144
LPAR2 lysophosphatidic acid receptor 2 4.56036
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 4.53984
CAPN1 calpain 1, (mu/I) large subunit 4.44555
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.40084
NANOS3 nanos homolog 3 (Drosophila) 4.39357
SYNGR3 synaptogyrin 3 4.27449
RBM12B RNA binding motif protein 12B 4.03614
CBR1 carbonyl reductase 1 4.0243
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.95674
TIAM1 T-cell lymphoma invasion and metastasis 1 3.94192
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.76024
COL4A1 collagen, type IV, alpha 1 3.71409
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 3.71008
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 3.66293
JADE2 jade family PHD finger 2 3.62491
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 3.5853
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) 3.57654
IL1B interleukin 1, beta 3.56092
AMDHD2 amidohydrolase domain containing 2 3.51391
KIFBP kinesin family binding protein 3.48985
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 3.42436
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.41318
IKZF1 IKAROS family zinc finger 1 (Ikaros) 3.33959
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 3.28328
MINDY1 MINDY lysine 48 deubiquitinase 1 3.24427
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.24275
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 3.17124
EPHA3 EPH receptor A3 3.14217
DGKB diacylglycerol kinase, beta 90kDa 3.11899
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.07851
PPP4R3A protein phosphatase 4 regulatory subunit 3A 3.0706
PSKH1 protein serine kinase H1 3.06073
BUB1B-PAK6 BUB1B-PAK6 readthrough 3.01482
ASL argininosuccinate lyase 2.99216
CDH20 cadherin 20, type 2 2.9827
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 2.98053
TBP TATA box binding protein 2.97691
TSPYL4 TSPY-like 4 2.9202
ZNF276 zinc finger protein 276 2.90043
ZFYVE21 zinc finger, FYVE domain containing 21 2.89458
ERMP1 endoplasmic reticulum metallopeptidase 1 2.88343
MSRA methionine sulfoxide reductase A 2.87888
MMP2 matrix metallopeptidase 2 2.87687
BTK Bruton agammaglobulinemia tyrosine kinase 2.87515
RRAGA Ras-related GTP binding A 2.87466
MAP3K4 mitogen-activated protein kinase kinase kinase 4 2.87001
IL24 interleukin 24 2.85162
TH tyrosine hydroxylase 2.84465
CRK v-crk avian sarcoma virus CT10 oncogene homolog 2.84366
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2 2.83849
DCAF4 DDB1 and CUL4 associated factor 4 2.83725
EHMT1 euchromatic histone-lysine N-methyltransferase 1 2.83603
CPEB3 cytoplasmic polyadenylation element binding protein 3 2.81335
DOP1B DOP1 leucine zipper like protein B 2.80233
CNPY3-GNMT CNPY3-GNMT readthrough 2.77919
YBX2 Y box binding protein 2 2.75507
PRR15L proline rich 15-like 2.74561
CUZD1 CUB and zona pellucida-like domains 1 2.73762
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.73712
NUP133 nucleoporin 133kDa 2.73497
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 2.71605
KAT6B K(lysine) acetyltransferase 6B 2.7127
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 2.70761
ARL4C ADP-ribosylation factor-like 4C 2.69927
CLDN3 claudin 3 2.6784
RHOA ras homolog family member A 2.6782
KLK15 kallikrein-related peptidase 15 2.66125
RBBP5 retinoblastoma binding protein 5 2.65861
CINP cyclin-dependent kinase 2 interacting protein 2.65806
HOXA10-HOXA9 HOXA10-HOXA9 readthrough 2.65433
SKIC8 SKI8 subunit of superkiller complex 2.65428
GARRE1 granule associated Rac and RHOG effector 1 2.64701
LCMT2 leucine carboxyl methyltransferase 2 2.64151
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 2.63852
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.63407
PLA2G12A phospholipase A2, group XIIA 2.62934
LMTK2 lemur tyrosine kinase 2 2.62271
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 2.62218
CCNG1 cyclin G1 2.60973
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 2.60599
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 2.60254
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 2.5938
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 2.59006
PRSS58 protease, serine, 58 2.58464
CELA2A chymotrypsin-like elastase family, member 2A 2.58397
RANBP17 RAN binding protein 17 2.58067
SRD5A3 steroid 5 alpha-reductase 3 2.57084
IL2RA interleukin 2 receptor, alpha 2.56657
SMR3A submaxillary gland androgen regulated protein 3A 2.56097
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 2.55128
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 2.53262
TDP1 tyrosyl-DNA phosphodiesterase 1 2.52641
CHODL chondrolectin 2.52475
ACR acrosin 2.52438
DNASE2B deoxyribonuclease II beta 2.52365
MSTN myostatin 2.52298
MTUS2 microtubule associated tumor suppressor candidate 2 2.5113
GPR171 G protein-coupled receptor 171 2.5113
CYB5RL cytochrome b5 reductase-like 2.50033
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.49557
COL4A2 collagen, type IV, alpha 2 2.49538
SMR3B submaxillary gland androgen regulated protein 3B 2.48644
GTF2IRD2B GTF2I repeat domain containing 2B 2.48563
CD22 CD22 molecule 2.47562
GPR75 G protein-coupled receptor 75 2.47403
RAMP1 receptor (G protein-coupled) activity modifying protein 1 2.47265
TSPAN6 tetraspanin 6 2.46691
TCHH trichohyalin 2.46245
KLRC4 killer cell lectin-like receptor subfamily C, member 4 2.4586
STAB1 stabilin 1 2.45544
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.45113
GPR6 G protein-coupled receptor 6 2.45017
PTK2 protein tyrosine kinase 2 2.44677
AQP5 aquaporin 5 2.44655
STEAP4 STEAP family member 4 2.44632
IKZF3 IKAROS family zinc finger 3 (Aiolos) 2.44342
ABHD18 abhydrolase domain containing 18 2.44193
KLK1 kallikrein 1 2.44065
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 2.43158
TUBA8 tubulin, alpha 8 2.42978
SKI SKI proto-oncogene 2.42765
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 2.42746
GPR183 G protein-coupled receptor 183 2.42374
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 2.42135
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2.42074
CST2 cystatin SA 2.41345
CALML5 calmodulin-like 5 2.41047
METTL16 methyltransferase like 16 2.40561
RORB RAR-related orphan receptor B 2.40537
HPCAL4 hippocalcin like 4 2.4046
MBTD1 mbt domain containing 1 2.40264
DMRT1 doublesex and mab-3 related transcription factor 1 2.39668
ACADSB acyl-CoA dehydrogenase, short/branched chain 2.39516
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C 2.39491
PLA2G1B phospholipase A2, group IB (pancreas) 2.39277
GP5 glycoprotein V (platelet) 2.39274
SHH sonic hedgehog 2.38969
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.36986
SIRPG signal-regulatory protein gamma 2.36938
LYRM2 LYR motif containing 2 2.36764
MED31 mediator complex subunit 31 2.36479
CLCN1 chloride channel, voltage-sensitive 1 2.35998
ZNF623 zinc finger protein 623 2.35899
ATP10A ATPase, class V, type 10A 2.35199
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 2.34781
LCT lactase 2.34617
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 2.34465
WTAP Wilms tumor 1 associated protein 2.34024
CXCL12 chemokine (C-X-C motif) ligand 12 2.33722
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 2.33076
SLC44A4 solute carrier family 44, member 4 2.32332
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 2.32248
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 2.32159
OR1A1 olfactory receptor, family 1, subfamily A, member 1 2.32116
NHP2 NHP2 ribonucleoprotein 2.32074
EPHX3 epoxide hydrolase 3 2.31834
LMX1B LIM homeobox transcription factor 1, beta 2.31813
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 2.31744
GPR20 G protein-coupled receptor 20 2.31214
WDFY3 WD repeat and FYVE domain containing 3 2.31213
CEP70 centrosomal protein 70kDa 2.30695
SIPA1L1 signal-induced proliferation-associated 1 like 1 2.3042
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 2.2971
ZC2HC1C zinc finger, C2HC-type containing 1C 2.29494
SNAI1 snail family zinc finger 1 2.29024
TMEM184C transmembrane protein 184C 2.28793
OPLAH 5-oxoprolinase (ATP-hydrolysing) 2.28662
OR2B2 olfactory receptor, family 2, subfamily B, member 2 2.28463
CXCL6 chemokine (C-X-C motif) ligand 6 2.28442
MAGIX MAGI family member, X-linked 2.28192
SCG5 secretogranin V 2.28143
F2R coagulation factor II (thrombin) receptor 2.28105
ATP5MC3 ATP synthase membrane subunit c locus 3 2.28047
AKR1D1 aldo-keto reductase family 1, member D1 2.27814
NPY neuropeptide Y 2.27397
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 2.27224
GPATCH2L G patch domain containing 2-like 2.27114
GSTCD glutathione S-transferase, C-terminal domain containing 2.27052
RPL36A ribosomal protein L36a 2.25777
OTUD7B OTU deubiquitinase 7B 2.25523
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 2.25403
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 2.25135
SYCP1 synaptonemal complex protein 1 2.24983
PNLIP pancreatic lipase 2.24922
LIPG lipase, endothelial 2.24803
TSPYL1 TSPY-like 1 2.24711
SPATA1 spermatogenesis associated 1 2.24453
CH25H cholesterol 25-hydroxylase 2.24332
ERCC6 excision repair cross-complementation group 6 2.24322
CDKL3 cyclin-dependent kinase-like 3 2.2365
ZNF780A zinc finger protein 780A 2.23512
LOC107985101 uncharacterized LOC107985101 2.2338
ALDOC aldolase C, fructose-bisphosphate 2.23247
PHAF1 phagosome assembly factor 1 2.2319
ZKSCAN2 zinc finger with KRAB and SCAN domains 2 2.22492
ADPRH ADP-ribosylarginine hydrolase 2.22191
INSIG1 insulin induced gene 1 2.21914
VPREB1 pre-B lymphocyte 1 2.21224
GPR68 G protein-coupled receptor 68 2.21126
SOX30 SRY (sex determining region Y)-box 30 2.20982
MEOX1 mesenchyme homeobox 1 2.20459
TESMIN testis expressed metallothionein like protein 2.20353
MAGEL2 melanoma antigen family L2 2.20271
BZW2 basic leucine zipper and W2 domains 2 2.20109
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 2.20015
LOC124900388 uncharacterized LOC124900388 2.19929
KCNK7 potassium channel, two pore domain subfamily K, member 7 2.19785
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 2.19249
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 2.1916
AIG1 androgen-induced 1 2.18916
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 2.18781
MALT1 MALT1 paracaspase 2.18696
MXRA7 matrix-remodelling associated 7 2.18677
CCNO cyclin O 2.18669
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 2.18
TEX12 testis expressed 12 2.17988
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.17875
SLBP stem-loop binding protein 2.17681
PDE3A phosphodiesterase 3A, cGMP-inhibited 2.17543
TRIM58 tripartite motif containing 58 2.17456
TRPC5 transient receptor potential cation channel, subfamily C, member 5 2.17434
POM121 POM121 transmembrane nucleoporin 2.17384
OR1A2 olfactory receptor, family 1, subfamily A, member 2 2.17141
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.17068
ADNP activity-dependent neuroprotector homeobox 2.16173
CTRC chymotrypsin C (caldecrin) 2.16064
PRKCG protein kinase C, gamma 2.15913
ZBTB6 zinc finger and BTB domain containing 6 2.15906
ASF1A anti-silencing function 1A histone chaperone 2.15664
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 2.1562
TDRD1 tudor domain containing 1 2.15561
CTRL chymotrypsin-like 2.14939
GLRX5 glutaredoxin 5 2.14669
NEU2 sialidase 2 (cytosolic sialidase) 2.14573
BBS10 Bardet-Biedl syndrome 10 2.14414
CELA2B chymotrypsin-like elastase family, member 2B 2.14392
SIPA1 signal-induced proliferation-associated 1 2.14361
YPEL1 yippee-like 1 (Drosophila) 2.14245
ADGRF1 adhesion G protein-coupled receptor F1 2.14134
MC5R melanocortin 5 receptor 2.14031
TM7SF2 transmembrane 7 superfamily member 2 2.14006
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 2.13834
IL12A interleukin 12A 2.13656
CCKBR cholecystokinin B receptor 2.13641
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.13193
HAVCR1 hepatitis A virus cellular receptor 1 2.12993
FOXD2 forkhead box D2 2.12959
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 2.12948
ZBTB7B zinc finger and BTB domain containing 7B 2.129
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.1264
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.12135
ATP2A3 ATPase, Ca++ transporting, ubiquitous 2.12129
ETNK2 ethanolamine kinase 2 2.11999
SPATA6L spermatogenesis associated 6-like 2.11847
UNC93A unc-93 homolog A (C. elegans) 2.11827
PADI1 peptidyl arginine deiminase, type I 2.11398
GDF7 growth differentiation factor 7 2.11381
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 2.11233
AUTS2 autism susceptibility candidate 2 2.11022
DCAF13 DDB1 and CUL4 associated factor 13 2.10895
SCYL3 SCY1-like 3 (S. cerevisiae) 2.1078
POM121L2 POM121 transmembrane nucleoporin-like 2 2.09992
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 2.09944
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 2.09592
COMT catechol-O-methyltransferase 2.09477
HOXA11 homeobox A11 2.08995
GPR132 G protein-coupled receptor 132 2.08984
SOX3 SRY (sex determining region Y)-box 3 2.08961
NNAT neuronatin 2.08865
PRKN parkin RBR E3 ubiquitin protein ligase 2.08838
SOCS4 suppressor of cytokine signaling 4 2.08823
IL11 interleukin 11 2.08798
SCAF8 SR-related CTD-associated factor 8 2.08731
LRRN3 leucine rich repeat neuronal 3 2.0856
SNTG2 syntrophin, gamma 2 2.08537
APOF apolipoprotein F 2.08393
TENM4 teneurin transmembrane protein 4 2.08121
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 2.081
CD5L CD5 molecule-like 2.08095
KCNK13 potassium channel, two pore domain subfamily K, member 13 2.08067
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 2.07844
ANKFY1 ankyrin repeat and FYVE domain containing 1 2.07646
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 2.07629
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 2.07598
POU3F4 POU class 3 homeobox 4 2.07527
MAGED1 melanoma antigen family D1 2.07437
GCM1 glial cells missing homolog 1 (Drosophila) 2.07188
ANKRD7 ankyrin repeat domain 7 2.07057
TRPC4 transient receptor potential cation channel, subfamily C, member 4 2.06928
HOXB13 homeobox B13 2.06674
CMKLR2 chemerin chemokine-like receptor 2 2.06594
KLHL22 kelch-like family member 22 2.06521
SNAP91 synaptosomal-associated protein, 91kDa 2.06492
BICC1 BicC family RNA binding protein 1 2.06481
TLX2 T-cell leukemia homeobox 2 2.06359
CAMKV CaM kinase-like vesicle-associated 2.06322
SPX spexin hormone 2.05868
ZIM2 zinc finger, imprinted 2 2.05633
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 2.05468
STXBP1 syntaxin binding protein 1 2.05426
UBQLN3 ubiquilin 3 2.05344
AMELY amelogenin, Y-linked 2.05309
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 2.0527
IPCEF1 interaction protein for cytohesin exchange factors 1 2.04943
DSCAM Down syndrome cell adhesion molecule 2.04828
NSUN7 NOP2/Sun domain family, member 7 2.04759
HMHB1 histocompatibility (minor) HB-1 2.04601
FZD1 frizzled class receptor 1 2.04514
LOC100996750 keratin-associated protein 4-7 2.04379
LPA lipoprotein, Lp(a) 2.0437
GRTP1 growth hormone regulated TBC protein 1 2.0433
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 2.04264
LOXL1 lysyl oxidase-like 1 2.04186
PRSS2 protease, serine, 2 (trypsin 2) 2.04179
SIX1 SIX homeobox 1 2.04147
CASP6 caspase 6, apoptosis-related cysteine peptidase 2.04023
CLUL1 clusterin-like 1 (retinal) 2.03864
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 2.03722
EPM2AIP1 EPM2A (laforin) interacting protein 1 2.03264
C18ORF25 chromosome 18 open reading frame 25 2.03149
ADORA2A adenosine A2a receptor 2.03094
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 2.02724
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 2.02526
PLPPR1 phospholipid phosphatase related 1 2.02507
OPRM1 opioid receptor, mu 1 2.023
RAB3D RAB3D, member RAS oncogene family 2.02295
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 2.02287
ZNF157 zinc finger protein 157 2.02272
YAF2 YY1 associated factor 2 2.02118
DCHS2 dachsous cadherin-related 2 2.02092
PRH1-TAS2R14 PRH1-TAS2R14 readthrough 2.01914
ZNF507 zinc finger protein 507 2.01676
PPP4R3B protein phosphatase 4 regulatory subunit 3B 2.01615
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 2.0159
HAPSTR1 HUWE1 associated protein modifying stress responses 2.01515
ZNF613 zinc finger protein 613 2.01506
SPATA31C1 SPATA31 subfamily C, member 1 2.01079
OLFML2B olfactomedin-like 2B 2.00696
DGKE diacylglycerol kinase, epsilon 64kDa 2.00601
HSPA2 heat shock 70kDa protein 2 2.00594
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 2.00468

decreased expression

Symbol Name Standardized Value
LOC124907782 dual specificity protein phosphatase 22 -9.66953
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -9.47742
NGRN neugrin, neurite outgrowth associated -8.78616
CAB39 calcium binding protein 39 -7.73859
CHMP4B charged multivesicular body protein 4B -6.22643
ANKRD10 ankyrin repeat domain 10 -5.76615
MRPS2 mitochondrial ribosomal protein S2 -5.3819
DUSP6 dual specificity phosphatase 6 -5.3171
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -5.2319
KDM3A lysine (K)-specific demethylase 3A -5.06673
ZNF586 zinc finger protein 586 -5.0405
ACOT9 acyl-CoA thioesterase 9 -5.00175
ARID5B AT rich interactive domain 5B (MRF1-like) -4.98848
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.88757
HMG20B high mobility group 20B -4.78881
ZW10 zw10 kinetochore protein -4.77101
NUP85 nucleoporin 85kDa -4.7564
RPS4Y1 ribosomal protein S4, Y-linked 1 -4.75398
CDC25B cell division cycle 25B -4.72168
DSG2 desmoglein 2 -4.3014
PEG10 paternally expressed 10 -4.20582
HYOU1 hypoxia up-regulated 1 -4.14942
NCK1 NCK adaptor protein 1 -4.12003
CD320 CD320 molecule -4.01049
YME1L1 YME1-like 1 ATPase -3.89729
PRKCD protein kinase C, delta -3.67184
GLOD4 glyoxalase domain containing 4 -3.64454
C2CD5 C2 calcium-dependent domain containing 5 -3.62709
CARMIL1 capping protein regulator and myosin 1 linker 1 -3.53546
CSK c-src tyrosine kinase -3.28925
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -3.25514
TBX2 T-box 2 -3.24744
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -3.12706
INHBE inhibin, beta E -3.07439
KCTD2 potassium channel tetramerization domain containing 2 -3.03225
GSAP gamma-secretase activating protein -2.99298
TMEM109 transmembrane protein 109 -2.96702
PHF21A PHD finger protein 21A -2.95668
FBXL12 F-box and leucine-rich repeat protein 12 -2.93918
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -2.93665
GFOD1 glucose-fructose oxidoreductase domain containing 1 -2.90692
BIRC2 baculoviral IAP repeat containing 2 -2.88607
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.82756
DUSP14 dual specificity phosphatase 14 -2.79769
EPS8L3 EPS8-like 3 -2.76945
PROSER1 proline and serine rich 1 -2.74949
RAB21 RAB21, member RAS oncogene family -2.74909
GTPBP8 GTP-binding protein 8 (putative) -2.74448
TCTN1 tectonic family member 1 -2.72553
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.72203
MTPAP mitochondrial poly(A) polymerase -2.72037
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 -2.64218
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough -2.6216
CRYZ crystallin, zeta (quinone reductase) -2.61492
PARP4 poly (ADP-ribose) polymerase family, member 4 -2.60651
PTPN6 protein tyrosine phosphatase, non-receptor type 6 -2.60312
SYNM synemin, intermediate filament protein -2.58815
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -2.57293
NGLY1 N-glycanase 1 -2.55751
ATF5 activating transcription factor 5 -2.55298
CARS1 cysteinyl-tRNA synthetase 1 -2.54857
MRPS7 mitochondrial ribosomal protein S7 -2.54387
IRF3 interferon regulatory factor 3 -2.53167
THOC1 THO complex 1 -2.49774
PLS3 plastin 3 -2.49375
TOR1A torsin family 1, member A (torsin A) -2.49047
TDRD7 tudor domain containing 7 -2.48668
PIEZO2 piezo-type mechanosensitive ion channel component 2 -2.48549
GMPPA GDP-mannose pyrophosphorylase A -2.48403
BTBD1 BTB (POZ) domain containing 1 -2.47378
FBXO46 F-box protein 46 -2.4634
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -2.45636
ETNK1 ethanolamine kinase 1 -2.43627
LAMB3 laminin, beta 3 -2.43291
MED22 mediator complex subunit 22 -2.4325
RNF103-CHMP3 RNF103-CHMP3 readthrough -2.43237
SCAMP5 secretory carrier membrane protein 5 -2.43062
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 -2.43026
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.42895
GTPBP2 GTP binding protein 2 -2.42586
MUTYH mutY homolog -2.41012
YIPF1 Yip1 domain family, member 1 -2.39053
COPS7B COP9 signalosome subunit 7B -2.38134
CCNB1 cyclin B1 -2.3758
ABI1 abl-interactor 1 -2.37314
RAD23B RAD23 homolog B (S. cerevisiae) -2.35581
PPP1R26 protein phosphatase 1, regulatory subunit 26 -2.35113
MARF1 meiosis regulator and mRNA stability factor 1 -2.33909
NOL11 nucleolar protein 11 -2.33385
ZNF580 zinc finger protein 580 -2.32194
WBP2 WW domain binding protein 2 -2.31022
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -2.30696
INTS13 integrator complex subunit 13 -2.30425
TRIP4 thyroid hormone receptor interactor 4 -2.28915
RIC8A RIC8 guanine nucleotide exchange factor A -2.28889
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -2.27215
FAM50A family with sequence similarity 50, member A -2.26214
TBC1D10C TBC1 domain family, member 10C -2.26095
ZC3H7A zinc finger CCCH-type containing 7A -2.26091
H2AC6 H2A clustered histone 6 -2.25843
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.24875
ILKAP integrin-linked kinase-associated serine/threonine phosphatase -2.2459
THSD1 thrombospondin, type I, domain containing 1 -2.2432
CCDC86 coiled-coil domain containing 86 -2.22754
KCMF1 potassium channel modulatory factor 1 -2.22091
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.21617
CCP110 centriolar coiled coil protein 110kDa -2.2157
XPOT exportin, tRNA -2.21111
RAB9A RAB9A, member RAS oncogene family -2.20847
ZNF324 zinc finger protein 324 -2.20721
MRPL58 mitochondrial ribosomal protein L58 -2.20285
CERK ceramide kinase -2.20246
SEC16A SEC16 homolog A (S. cerevisiae) -2.20152
SAFB2 scaffold attachment factor B2 -2.19531
BLMH bleomycin hydrolase -2.1902
RAI14 retinoic acid induced 14 -2.18923
FERRY3 FERRY endosomal RAB5 effector complex subunit 3 -2.18594
TUBB2B tubulin, beta 2B class IIb -2.1855
HAX1 HCLS1 associated protein X-1 -2.18297
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 -2.16961
COMMD3 COMM domain containing 3 -2.16752
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.16728
CCL20 chemokine (C-C motif) ligand 20 -2.16589
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.16454
ZNF706 zinc finger protein 706 -2.1622
SRBD1 S1 RNA binding domain 1 -2.15636
TMEM94 transmembrane protein 94 -2.15276
RPIA ribose 5-phosphate isomerase A -2.12783
TUT7 terminal uridylyl transferase 7 -2.12302
DENND1B DENN/MADD domain containing 1B -2.12122
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -2.10803
CDC16 cell division cycle 16 -2.10773
MAN1B1 mannosidase, alpha, class 1B, member 1 -2.10388
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow -2.10152
NLRP4 NLR family, pyrin domain containing 4 -2.09423
DUSP8 dual specificity phosphatase 8 -2.09244
MSH2 mutS homolog 2 -2.08687
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -2.08535
ANKRD49 ankyrin repeat domain 49 -2.08162
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -2.0796
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.07322
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 -2.0714
EXOSC8 exosome component 8 -2.06744
TNNC2 troponin C type 2 (fast) -2.04361
PPP1R3C protein phosphatase 1, regulatory subunit 3C -2.04032
GTF3A general transcription factor IIIA -2.03437
PEX26 peroxisomal biogenesis factor 26 -2.03434
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.02648
MEAF6 MYST/Esa1-associated factor 6 -2.02359
AKAP8 A kinase (PRKA) anchor protein 8 -2.02062
ANAPC2 anaphase promoting complex subunit 2 -2.0141
EXOSC5 exosome component 5 -2.01404
HMGN4 high mobility group nucleosomal binding domain 4 -2.00176