| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-(2-bromo-2-ethylbutanoyl)urea 10.12 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN009_HEPG2_24H:I20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 6.24714 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 5.53295 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.46978 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.02454 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.82847 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.62475 |
| CBR3 | carbonyl reductase 3 | 4.39517 |
| HOXA10 | homeobox A10 | 4.12316 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.08054 |
| DENND2D | DENN/MADD domain containing 2D | 4.00466 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.8008 |
| ABHD6 | abhydrolase domain containing 6 | 3.5392 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.34805 |
| MAP7 | microtubule-associated protein 7 | 3.20395 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 3.03036 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.02315 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.97165 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.78818 |
| FAIM | Fas apoptotic inhibitory molecule | 2.68705 |
| RAB4A | RAB4A, member RAS oncogene family | 2.66836 |
| JADE2 | jade family PHD finger 2 | 2.58335 |
| ATP11B | ATPase, class VI, type 11B | 2.56676 |
| CYB561 | cytochrome b561 | 2.49342 |
| ANO10 | anoctamin 10 | 2.21517 |
| CRTAP | cartilage associated protein | 2.20709 |
| PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | 2.16744 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 2.07271 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 2.05426 |
| STXBP2 | syntaxin binding protein 2 | 2.05176 |
| EMC3 | ER membrane protein complex subunit 3 | 2.03622 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled | 2.01823 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -9.54671 |
| TRIB3 | tribbles pseudokinase 3 | -5.11441 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.98631 |
| GTPBP8 | GTP-binding protein 8 (putative) | -4.95538 |
| ZNF586 | zinc finger protein 586 | -4.4703 |
| CDC20 | cell division cycle 20 | -4.28685 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.24563 |
| EGF | epidermal growth factor | -4.16144 |
| PEG10 | paternally expressed 10 | -4.08971 |
| HMG20B | high mobility group 20B | -3.5514 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.51862 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.84428 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.67619 |
| TEAD3 | TEA domain family member 3 | -2.38845 |
| UBA5 | ubiquitin-like modifier activating enzyme 5 | -2.30326 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.16007 |
| SOX12 | SRY (sex determining region Y)-box 12 | -2.08455 |
| ZNF668 | zinc finger protein 668 | -2.0745 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | -2.06807 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 | -2.0505 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | -2.04861 |
| CDIP1 | cell death-inducing p53 target 1 | -2.04051 |
| RBM4B | RNA binding motif protein 4B | -2.0345 |
