| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-(2-bromo-2-ethylbutanoyl)urea 2.53 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
52 genes differentially expressed following the CRCGN009_HEPG2_24H:I22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 5.01395 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.28484 |
| SFTPB | surfactant protein B | 4.22837 |
| MEST | mesoderm specific transcript | 3.78939 |
| KLHL9 | kelch-like family member 9 | 3.27153 |
| TBC1D31 | TBC1 domain family, member 31 | 3.17395 |
| MAP7 | microtubule-associated protein 7 | 3.0347 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.86768 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.76644 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.75898 |
| KIF20A | kinesin family member 20A | 2.73067 |
| EGF | epidermal growth factor | 2.6514 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.55548 |
| MCM3 | minichromosome maintenance complex component 3 | 2.42072 |
| PPP4C | protein phosphatase 4, catalytic subunit | 2.41445 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.40809 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.35889 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.35477 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.33849 |
| CHN1 | chimerin 1 | 2.30152 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.22626 |
| LDHC | lactate dehydrogenase C | 2.21252 |
| DIPK1A | divergent protein kinase domain 1A | 2.17831 |
| NUBPL | nucleotide binding protein-like | 2.14621 |
| TMEM254 | transmembrane protein 254 | 2.13425 |
| BAX | BCL2-associated X protein | 2.12539 |
| NCAPH | non-SMC condensin I complex, subunit H | 2.09715 |
| PHOSPHO2-KLHL23 | PHOSPHO2-KLHL23 readthrough | 2.08292 |
| COPS7A | COP9 signalosome subunit 7A | 2.07397 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -7.54483 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -4.85553 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -4.78876 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.60172 |
| TSPAN4 | tetraspanin 4 | -4.41902 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -4.41785 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.34479 |
| ZW10 | zw10 kinetochore protein | -3.35723 |
| NGRN | neugrin, neurite outgrowth associated | -3.34313 |
| CSK | c-src tyrosine kinase | -3.3221 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.81488 |
| YME1L1 | YME1-like 1 ATPase | -2.81383 |
| TCTN1 | tectonic family member 1 | -2.64605 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.64474 |
| BIRC2 | baculoviral IAP repeat containing 2 | -2.59384 |
| TLCD3A | TLC domain containing 3A | -2.58786 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.54424 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.37739 |
| VTN | vitronectin | -2.23079 |
| ILK | integrin-linked kinase | -2.04803 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 | -2.01304 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.01034 |
| GDF3 | growth differentiation factor 3 | -2.00796 |
