CRCGN009_HEPG2_24H:I23 Gene Set
Genes
48 genes differentially expressed following the CRCGN009_HEPG2_24H:I23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
10.0
|
|
ATP11B
|
ATPase, class VI, type 11B
|
5.51889
|
|
ZNF589
|
zinc finger protein 589
|
5.3469
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
5.02697
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.02385
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.81766
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.50112
|
|
UBQLN2
|
ubiquilin 2
|
4.09401
|
|
NUCB2
|
nucleobindin 2
|
4.05566
|
|
CYCS
|
cytochrome c, somatic
|
3.57343
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.43557
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.06382
|
|
SFTPB
|
surfactant protein B
|
2.93684
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.84285
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.73143
|
|
ADGRG1
|
adhesion G protein-coupled receptor G1
|
2.61887
|
|
POLG2
|
polymerase (DNA directed), gamma 2, accessory subunit
|
2.57689
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.34755
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.33388
|
|
GPATCH8
|
G patch domain containing 8
|
2.32833
|
|
TBC1D31
|
TBC1 domain family, member 31
|
2.27954
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
2.16864
|
|
SNX7
|
sorting nexin 7
|
2.10288
|
|
BMP4
|
bone morphogenetic protein 4
|
2.03162
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-7.51986
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.56376
|
|
CDC20
|
cell division cycle 20
|
-5.49161
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-5.36219
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-5.02087
|
|
CCDC86
|
coiled-coil domain containing 86
|
-5.01748
|
|
LAP3
|
leucine aminopeptidase 3
|
-4.94916
|
|
LDHD
|
lactate dehydrogenase D
|
-4.6894
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.54763
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.42807
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.00143
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
-3.36328
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.29814
|
|
CCNB2
|
cyclin B2
|
-2.99263
|
|
GNAS
|
GNAS complex locus
|
-2.88205
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.8076
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.44985
|
|
RNF167
|
ring finger protein 167
|
-2.40104
|
|
AFF4
|
AF4/FMR2 family, member 4
|
-2.34714
|
|
PLA2G2D
|
phospholipase A2, group IID
|
-2.15071
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.0731
|
|
IL33
|
interleukin 33
|
-2.06067
|
|
ATF7
|
activating transcription factor 7
|
-2.00484
|
|
SPAG4
|
sperm associated antigen 4
|
-2.00391
|
