CRCGN009_HEPG2_24H:I24 Gene Set
Genes
51 genes differentially expressed following the CRCGN009_HEPG2_24H:I24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.26115
|
|
ZNF589
|
zinc finger protein 589
|
5.25515
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
4.62646
|
|
LCN2
|
lipocalin 2
|
3.94756
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.86693
|
|
MAP7
|
microtubule-associated protein 7
|
3.74486
|
|
PRKCH
|
protein kinase C, eta
|
3.58108
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.51394
|
|
PRR15L
|
proline rich 15-like
|
3.31095
|
|
CHN1
|
chimerin 1
|
3.25139
|
|
STK10
|
serine/threonine kinase 10
|
3.10615
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.84551
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.7894
|
|
EVL
|
Enah/Vasp-like
|
2.75712
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.40573
|
|
NOTCH1
|
notch 1
|
2.3822
|
|
SASH3
|
SAM and SH3 domain containing 3
|
2.33972
|
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
2.25228
|
|
ASCC3
|
activating signal cointegrator 1 complex subunit 3
|
2.18541
|
|
BLMH
|
bleomycin hydrolase
|
2.12609
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
2.1013
|
|
UBQLN2
|
ubiquilin 2
|
2.06511
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-7.50287
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-7.37229
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.86206
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.82538
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-4.2794
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.0767
|
|
HYOU1
|
hypoxia up-regulated 1
|
-3.9521
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.78347
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.59755
|
|
ZNF586
|
zinc finger protein 586
|
-3.4807
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.37769
|
|
SNX11
|
sorting nexin 11
|
-2.91348
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.74892
|
|
CD320
|
CD320 molecule
|
-2.71706
|
|
CAB39
|
calcium binding protein 39
|
-2.65837
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.65424
|
|
CSK
|
c-src tyrosine kinase
|
-2.52644
|
|
GOLT1B
|
golgi transport 1B
|
-2.37815
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.33426
|
|
CDC20
|
cell division cycle 20
|
-2.31541
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.30313
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.24858
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-2.23434
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
-2.21672
|
|
LDHD
|
lactate dehydrogenase D
|
-2.1544
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.11411
|
|
STIMATE
|
STIM activating enhancer
|
-2.10246
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.05025
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.03696
|
