| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-[2,2-dichloro-1-(4-ethylphenyl)ethyl]-4-ethylbenzene 10.36 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN009_HEPG2_24H:J02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SNAP25 | synaptosomal-associated protein, 25kDa | 7.10671 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.1198 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.90606 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.85187 |
| RRAGA | Ras-related GTP binding A | 4.09409 |
| CHMP6 | charged multivesicular body protein 6 | 4.02905 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.87353 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.74343 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.89269 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 2.89147 |
| MEST | mesoderm specific transcript | 2.85119 |
| MCM3 | minichromosome maintenance complex component 3 | 2.77737 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.77527 |
| SKIC8 | SKI8 subunit of superkiller complex | 2.65178 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 2.63435 |
| GPATCH8 | G patch domain containing 8 | 2.60221 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.57581 |
| PUF60 | poly-U binding splicing factor 60KDa | 2.48805 |
| HSPB1 | heat shock 27kDa protein 1 | 2.43486 |
| AXIN1 | axin 1 | 2.41768 |
| WASF3 | WAS protein family, member 3 | 2.38108 |
| ECD | ecdysoneless homolog (Drosophila) | 2.28459 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 2.21061 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.19607 |
| CORO1A | coronin, actin binding protein, 1A | 2.02666 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -9.86403 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -6.58318 |
| PRPF4 | pre-mRNA processing factor 4 | -5.12032 |
| DNM1L | dynamin 1-like | -4.88976 |
| CDC20 | cell division cycle 20 | -4.52787 |
| RGS2 | regulator of G-protein signaling 2 | -4.49736 |
| NRIP1 | nuclear receptor interacting protein 1 | -4.29817 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.24579 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.9418 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.66678 |
| CD320 | CD320 molecule | -3.49199 |
| NISCH | nischarin | -3.48335 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.39149 |
| SNX11 | sorting nexin 11 | -2.87679 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.83356 |
| ANKRD10 | ankyrin repeat domain 10 | -2.80632 |
| TES | testin LIM domain protein | -2.80625 |
| HEATR1 | HEAT repeat containing 1 | -2.67454 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -2.5994 |
| TDRD7 | tudor domain containing 7 | -2.44478 |
| NCK2 | NCK adaptor protein 2 | -2.38798 |
| TLCD3A | TLC domain containing 3A | -2.378 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -2.27174 |
| STOM | stomatin | -2.25354 |
| TXNDC9 | thioredoxin domain containing 9 | -2.24559 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) | -2.10908 |
| IL12RB2 | interleukin 12 receptor, beta 2 | -2.10684 |
| SSTR3 | somatostatin receptor 3 | -2.09828 |
| TMCC2 | transmembrane and coiled-coil domain family 2 | -2.06363 |
| TMEM231 | transmembrane protein 231 | -2.05016 |
| MCM6 | minichromosome maintenance complex component 6 | -2.04647 |
| CLCN2 | chloride channel, voltage-sensitive 2 | -2.02905 |
| OSBPL1A | oxysterol binding protein-like 1A | -2.0184 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | -2.01609 |
