CRCGN009_HEPG2_24H:J05 Gene Set
Genes
41 genes differentially expressed following the CRCGN009_HEPG2_24H:J05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
3.85926
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.65264
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.5157
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.31941
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.19269
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
3.18421
|
|
CYCS
|
cytochrome c, somatic
|
3.10098
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.85842
|
|
CHN1
|
chimerin 1
|
2.71098
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.56634
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.35175
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.31387
|
|
SATB1
|
SATB homeobox 1
|
2.22638
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
2.22632
|
|
EGF
|
epidermal growth factor
|
2.13548
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.08159
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.26486
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-6.1081
|
|
CCNB1
|
cyclin B1
|
-5.04788
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.91701
|
|
COG7
|
component of oligomeric golgi complex 7
|
-3.83352
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.78954
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-3.67633
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.36605
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.31595
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.27863
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.19125
|
|
TLR4
|
toll-like receptor 4
|
-3.16467
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.10132
|
|
CCNB2
|
cyclin B2
|
-2.93372
|
|
WASHC4
|
WASH complex subunit 4
|
-2.90853
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.85869
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.60233
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.58162
|
|
GNAS
|
GNAS complex locus
|
-2.43673
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.41816
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
-2.31187
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.15062
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.15034
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.04982
|
|
HMG20B
|
high mobility group 20B
|
-2.01344
|
