CRCGN009_HEPG2_24H:J06 Gene Set
Genes
34 genes differentially expressed following the CRCGN009_HEPG2_24H:J06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
6.5805
|
|
UBQLN2
|
ubiquilin 2
|
6.17819
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.91188
|
|
STIMATE
|
STIM activating enhancer
|
4.20665
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.00405
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
3.59398
|
|
VGLL4
|
vestigial-like family member 4
|
3.49041
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.47337
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.30026
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
3.07858
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.76838
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.66064
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.6561
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.12878
|
|
GPATCH8
|
G patch domain containing 8
|
2.1194
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
FGFR4
|
fibroblast growth factor receptor 4
|
-5.56204
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.71496
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.69777
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.68691
|
|
CD320
|
CD320 molecule
|
-3.04295
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.02954
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.93307
|
|
TLR4
|
toll-like receptor 4
|
-2.66865
|
|
CCNB2
|
cyclin B2
|
-2.60275
|
|
PLK1
|
polo-like kinase 1
|
-2.57545
|
|
WASHC4
|
WASH complex subunit 4
|
-2.45993
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.4445
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.39547
|
|
TNP1
|
transition protein 1 (during histone to protamine replacement)
|
-2.34923
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.30501
|
|
EGF
|
epidermal growth factor
|
-2.22288
|
|
PRM2
|
protamine 2
|
-2.04115
|
|
NLRP4
|
NLR family, pyrin domain containing 4
|
-2.01796
|
|
PRKCG
|
protein kinase C, gamma
|
-2.0112
|
