| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dimpylate 20.91 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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67 genes differentially expressed following the CRCGN009_HEPG2_24H:J07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PNKP | polynucleotide kinase 3'-phosphatase | 7.66479 |
| NOTCH1 | notch 1 | 6.7963 |
| LCN2 | lipocalin 2 | 6.00125 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.23662 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.98954 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 4.68721 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.5937 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 4.12684 |
| ATP11B | ATPase, class VI, type 11B | 3.77368 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.46089 |
| MAP7 | microtubule-associated protein 7 | 3.39212 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.04854 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.9661 |
| DIPK1A | divergent protein kinase domain 1A | 2.90076 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.87891 |
| JADE2 | jade family PHD finger 2 | 2.71594 |
| PTOV1 | prostate tumor overexpressed 1 | 2.70186 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.68669 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.59907 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.58215 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 2.51934 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 2.45173 |
| TBP | TATA box binding protein | 2.42349 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.42332 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 2.34901 |
| SQOR | sulfide quinone oxidoreductase | 2.346 |
| PLPP3 | phospholipid phosphatase 3 | 2.32974 |
| TSEN34 | TSEN34 tRNA splicing endonuclease subunit | 2.32197 |
| ATAD2B | ATPase family, AAA domain containing 2B | 2.30631 |
| RPL39L | ribosomal protein L39-like | 2.30057 |
| ZFP36 | ZFP36 ring finger protein | 2.29794 |
| VAT1 | vesicle amine transport 1 | 2.20837 |
| UBQLN2 | ubiquilin 2 | 2.15976 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 2.01903 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | 2.00021 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -7.31212 |
| CCNB2 | cyclin B2 | -6.95922 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -6.56704 |
| NISCH | nischarin | -5.50761 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.39118 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -4.87678 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.77271 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -4.56717 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.2518 |
| TES | testin LIM domain protein | -4.11809 |
| PRPF4 | pre-mRNA processing factor 4 | -4.07344 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -4.0559 |
| SLC35F2 | solute carrier family 35, member F2 | -3.90002 |
| CCNB1 | cyclin B1 | -3.83556 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.36392 |
| CDC20 | cell division cycle 20 | -3.30361 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -3.27282 |
| GOLT1B | golgi transport 1B | -3.17 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -3.07355 |
| CD320 | CD320 molecule | -2.83146 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.61565 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.46834 |
| GNAS | GNAS complex locus | -2.18777 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -2.1633 |
| MMP13 | matrix metallopeptidase 13 | -2.15562 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.13758 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.11072 |
| CBX3 | chromobox homolog 3 | -2.1085 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -2.08733 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | -2.0591 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.05398 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.05283 |
