CRCGN009_HEPG2_24H:J10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimpylate 2.61 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

40 genes differentially expressed following the CRCGN009_HEPG2_24H:J10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 10.0
RPP38 ribonuclease P/MRP 38kDa subunit 6.87129
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 6.75765
ABHD6 abhydrolase domain containing 6 5.41025
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 4.68039
TBP TATA box binding protein 3.71162
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 3.636
JADE2 jade family PHD finger 2 3.38996
CHMP6 charged multivesicular body protein 6 3.34825
STIMATE STIM activating enhancer 3.25635
UBQLN2 ubiquilin 2 3.04832
MAP7 microtubule-associated protein 7 2.85413
CCL2 chemokine (C-C motif) ligand 2 2.82902
GATA3 GATA binding protein 3 2.68602
SEPHS1 selenophosphate synthetase 1 2.37964
CEP57 centrosomal protein 57kDa 2.34109
ADGRE5 adhesion G protein-coupled receptor E5 2.3058
CCNF cyclin F 2.30057
CIRBP cold inducible RNA binding protein 2.24814
CHN1 chimerin 1 2.20405
SKIC8 SKI8 subunit of superkiller complex 2.19719
PIH1D1 PIH1 domain containing 1 2.09203
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.08818
THAP1 THAP domain containing, apoptosis associated protein 1 2.00447

decreased expression

Symbol Name Standardized Value
KDM3A lysine (K)-specific demethylase 3A -7.26398
PCNA proliferating cell nuclear antigen -6.09252
CCNB2 cyclin B2 -4.87121
PTPRK protein tyrosine phosphatase, receptor type, K -4.56912
ITGB1BP1 integrin beta 1 binding protein 1 -4.13891
LAP3 leucine aminopeptidase 3 -4.08358
COG4 component of oligomeric golgi complex 4 -3.2727
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.78185
CCDC86 coiled-coil domain containing 86 -2.76569
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.66556
GNAS GNAS complex locus -2.62554
LOC124907782 dual specificity protein phosphatase 22 -2.62503
CCNB1 cyclin B1 -2.30263
PSRC1 proline/serine-rich coiled-coil 1 -2.29276
TXLNA taxilin alpha -2.18092
DERA deoxyribose-phosphate aldolase (putative) -2.15784