| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dimpylate 1.31 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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55 genes differentially expressed following the CRCGN009_HEPG2_24H:J11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SNAP25 | synaptosomal-associated protein, 25kDa | 5.756 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.18611 |
| EAPP | E2F-associated phosphoprotein | 4.54716 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.17013 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.127 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.02095 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.8299 |
| ZFP36 | ZFP36 ring finger protein | 3.7719 |
| LAGE3 | L antigen family, member 3 | 3.73124 |
| STK10 | serine/threonine kinase 10 | 3.72201 |
| UBQLN2 | ubiquilin 2 | 3.68376 |
| BLMH | bleomycin hydrolase | 3.48839 |
| MAMLD1 | mastermind-like domain containing 1 | 3.42007 |
| CCNF | cyclin F | 3.38594 |
| VGLL4 | vestigial-like family member 4 | 3.27061 |
| NOSIP | nitric oxide synthase interacting protein | 3.11795 |
| MAP7 | microtubule-associated protein 7 | 2.81988 |
| GPATCH8 | G patch domain containing 8 | 2.38991 |
| LCN2 | lipocalin 2 | 2.28402 |
| E2F2 | E2F transcription factor 2 | 2.27109 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 2.21642 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.13167 |
| STXBP2 | syntaxin binding protein 2 | 2.11854 |
| AAMP | angio-associated, migratory cell protein | 2.11757 |
| BAX | BCL2-associated X protein | 2.07116 |
| TBPL1 | TBP-like 1 | 2.06002 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.05861 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.04865 |
| GLRX5 | glutaredoxin 5 | 2.00231 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TLR4 | toll-like receptor 4 | -7.35707 |
| PCNA | proliferating cell nuclear antigen | -5.82758 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.39068 |
| SLC35F2 | solute carrier family 35, member F2 | -4.33996 |
| VAT1 | vesicle amine transport 1 | -4.26761 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.23598 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.21414 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.95962 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -3.66078 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.6306 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.3854 |
| HEATR1 | HEAT repeat containing 1 | -3.14259 |
| YME1L1 | YME1-like 1 ATPase | -3.05004 |
| CSK | c-src tyrosine kinase | -2.94304 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.66534 |
| NGRN | neugrin, neurite outgrowth associated | -2.63826 |
| GNAS | GNAS complex locus | -2.5528 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.5344 |
| SCAND1 | SCAN domain containing 1 | -2.50339 |
| CDC25B | cell division cycle 25B | -2.43572 |
| GTPBP8 | GTP-binding protein 8 (putative) | -2.42136 |
| BLCAP | bladder cancer associated protein | -2.23699 |
| RNF167 | ring finger protein 167 | -2.19309 |
| SNX11 | sorting nexin 11 | -2.1841 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -2.14062 |
| MAP1S | microtubule-associated protein 1S | -2.11001 |