| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dimpylate 0.65 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
58 genes differentially expressed following the CRCGN009_HEPG2_24H:J12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CBR3 | carbonyl reductase 3 | 9.45596 |
| MAP7 | microtubule-associated protein 7 | 5.19738 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.63293 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 4.44255 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.25838 |
| E2F2 | E2F transcription factor 2 | 4.05788 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 3.70568 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.58701 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.57423 |
| GATA3 | GATA binding protein 3 | 3.33148 |
| MYLK | myosin light chain kinase | 2.90625 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2.8834 |
| HOXA10 | homeobox A10 | 2.6801 |
| LCN2 | lipocalin 2 | 2.67506 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 2.66906 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.66391 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.61959 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.4775 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.46103 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.45736 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.33715 |
| JADE2 | jade family PHD finger 2 | 2.27195 |
| UPK1A | uroplakin 1A | 2.22087 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 2.15878 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) | 2.01143 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -7.07517 |
| MRPS2 | mitochondrial ribosomal protein S2 | -6.70376 |
| ADI1 | acireductone dioxygenase 1 | -6.58653 |
| CDC20 | cell division cycle 20 | -6.41615 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.44734 |
| CCNB1 | cyclin B1 | -4.11698 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.67103 |
| TSPAN4 | tetraspanin 4 | -3.62174 |
| EGF | epidermal growth factor | -3.01844 |
| CCNB2 | cyclin B2 | -2.95921 |
| CSK | c-src tyrosine kinase | -2.93576 |
| CAB39 | calcium binding protein 39 | -2.93212 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -2.84617 |
| PCNA | proliferating cell nuclear antigen | -2.79088 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.75454 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.70478 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.65285 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.64682 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.64401 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.6384 |
| TLCD3A | TLC domain containing 3A | -2.63329 |
| SLC35F2 | solute carrier family 35, member F2 | -2.52336 |
| STX4 | syntaxin 4 | -2.43452 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.41167 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.31504 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -2.2998 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.20686 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.20007 |
| SPON2 | spondin 2, extracellular matrix protein | -2.18286 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -2.13345 |
| SESN1 | sestrin 1 | -2.1179 |
| CENPE | centromere protein E, 312kDa | -2.10538 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.0802 |
