CRCGN009_HEPG2_24H:J16 Gene Set
Genes
36 genes differentially expressed following the CRCGN009_HEPG2_24H:J16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
7.08116
|
|
LCN2
|
lipocalin 2
|
5.50169
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.47476
|
|
SLC35A1
|
solute carrier family 35 (CMP-sialic acid transporter), member A1
|
3.33795
|
|
KLHL9
|
kelch-like family member 9
|
3.19114
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.16245
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.08924
|
|
RBKS
|
ribokinase
|
3.06798
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.9164
|
|
MYLK
|
myosin light chain kinase
|
2.87439
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.79909
|
|
MICALL1
|
MICAL-like 1
|
2.45241
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
2.43632
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.28669
|
|
GATA3
|
GATA binding protein 3
|
2.18032
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
2.16908
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.14519
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
2.07942
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-6.00177
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.85032
|
|
CSK
|
c-src tyrosine kinase
|
-3.49674
|
|
CCNB1
|
cyclin B1
|
-3.38026
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.25639
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.24504
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-3.03326
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-2.82619
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-2.78497
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.51844
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.47226
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.47093
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.43917
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.34569
|
|
LDHD
|
lactate dehydrogenase D
|
-2.33904
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.22417
|
|
CLIP4
|
CAP-GLY domain containing linker protein family, member 4
|
-2.11309
|
|
RGS18
|
regulator of G-protein signaling 18
|
-2.00371
|
