CRCGN009_HEPG2_24H:J18 Gene Set
Genes
46 genes differentially expressed following the CRCGN009_HEPG2_24H:J18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
10.0
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.1697
|
|
NOTCH1
|
notch 1
|
4.77195
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.66315
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.50455
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.415
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.8574
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.72003
|
|
STK10
|
serine/threonine kinase 10
|
3.35325
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
3.31102
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.9476
|
|
GATA3
|
GATA binding protein 3
|
2.85865
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.58975
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.57083
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.39449
|
|
CHEK2
|
checkpoint kinase 2
|
2.34674
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
2.33042
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.30227
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.29641
|
|
PTK2
|
protein tyrosine kinase 2
|
2.24356
|
|
NSMCE4A
|
non-SMC element 4 homolog A (S. cerevisiae)
|
2.18774
|
|
HEBP1
|
heme binding protein 1
|
2.12626
|
|
KLHL9
|
kelch-like family member 9
|
2.11131
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-7.94771
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.79801
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-5.11724
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-4.7354
|
|
CSK
|
c-src tyrosine kinase
|
-3.79873
|
|
GNAS
|
GNAS complex locus
|
-3.68307
|
|
PEG10
|
paternally expressed 10
|
-3.62651
|
|
EGF
|
epidermal growth factor
|
-3.61402
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-3.45315
|
|
HEATR1
|
HEAT repeat containing 1
|
-3.11538
|
|
CDC20
|
cell division cycle 20
|
-3.06103
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.74913
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.45622
|
|
SCMH1
|
sex comb on midleg homolog 1 (Drosophila)
|
-2.45032
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.31663
|
|
CRISP2
|
cysteine-rich secretory protein 2
|
-2.29084
|
|
CCNB2
|
cyclin B2
|
-2.286
|
|
TBX2
|
T-box 2
|
-2.27216
|
|
HTATSF1
|
HIV-1 Tat specific factor 1
|
-2.26824
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.14533
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.13276
|
|
NVL
|
nuclear VCP-like
|
-2.08507
|
|
CHST1
|
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
|
-2.05664
|
