| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | p-cresidine 9.7 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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61 genes differentially expressed following the CRCGN009_HEPG2_24H:K03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GSTZ1 | glutathione S-transferase zeta 1 | 6.07311 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.16342 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.75087 |
| CHMP6 | charged multivesicular body protein 6 | 4.54488 |
| MSRA | methionine sulfoxide reductase A | 4.42287 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 4.20744 |
| RPL39L | ribosomal protein L39-like | 4.17314 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.07497 |
| NOTCH1 | notch 1 | 3.99564 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.80486 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.79447 |
| EVL | Enah/Vasp-like | 3.53997 |
| STIMATE | STIM activating enhancer | 3.43005 |
| FCHO1 | FCH domain only 1 | 3.21679 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.13371 |
| LOC122526780 | uncharacterized LOC122526780 | 2.97296 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.94645 |
| KIF5C | kinesin family member 5C | 2.91965 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.75958 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.73304 |
| TPD52L2 | tumor protein D52-like 2 | 2.55263 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 2.40677 |
| CORO1A | coronin, actin binding protein, 1A | 2.38363 |
| JADE2 | jade family PHD finger 2 | 2.28328 |
| PLSCR3 | phospholipid scramblase 3 | 2.27002 |
| DIPK1A | divergent protein kinase domain 1A | 2.2383 |
| RANGRF | RAN guanine nucleotide release factor | 2.17211 |
| GPATCH8 | G patch domain containing 8 | 2.15803 |
| HEBP1 | heme binding protein 1 | 2.13441 |
| ZNF589 | zinc finger protein 589 | 2.06661 |
| CDK19 | cyclin-dependent kinase 19 | 2.06184 |
| ABHD3 | abhydrolase domain containing 3 | 2.01917 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -8.60193 |
| GTPBP8 | GTP-binding protein 8 (putative) | -4.83572 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.60873 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -4.32776 |
| SLC35F2 | solute carrier family 35, member F2 | -4.29262 |
| TLR4 | toll-like receptor 4 | -4.23643 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.20422 |
| GNAS | GNAS complex locus | -4.17456 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.14604 |
| GOLT1B | golgi transport 1B | -4.12175 |
| PCNA | proliferating cell nuclear antigen | -4.00939 |
| TES | testin LIM domain protein | -3.39084 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.03963 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -3.00248 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.9493 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.59608 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.58174 |
| NGRN | neugrin, neurite outgrowth associated | -2.46249 |
| CSK | c-src tyrosine kinase | -2.4148 |
| EGF | epidermal growth factor | -2.38524 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -2.37973 |
| RBM15B | RNA binding motif protein 15B | -2.24237 |
| MNS1 | meiosis-specific nuclear structural 1 | -2.23058 |
| HMG20B | high mobility group 20B | -2.20295 |
| CCNH | cyclin H | -2.16155 |
| TLCD3A | TLC domain containing 3A | -2.08486 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | -2.057 |
| PPOX | protoporphyrinogen oxidase | -2.01781 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.00835 |