| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | p-cresidine 4.85 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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69 genes differentially expressed following the CRCGN009_HEPG2_24H:K04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NOTCH1 | notch 1 | 8.01416 |
| PPARG | peroxisome proliferator-activated receptor gamma | 7.82258 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 7.3787 |
| CCDC92 | coiled-coil domain containing 92 | 5.10952 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.93395 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.84397 |
| MEF2C | myocyte enhancer factor 2C | 4.81428 |
| PRKCD | protein kinase C, delta | 4.65683 |
| FCHO1 | FCH domain only 1 | 4.22735 |
| ZNF589 | zinc finger protein 589 | 4.10873 |
| MELK | maternal embryonic leucine zipper kinase | 3.41624 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.4043 |
| VGLL4 | vestigial-like family member 4 | 3.36139 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.21898 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.14282 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.04446 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.98451 |
| TENT4A | terminal nucleotidyltransferase 4A | 2.87158 |
| CCDC85B | coiled-coil domain containing 85B | 2.67455 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.6284 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.60474 |
| PMM2 | phosphomannomutase 2 | 2.36864 |
| CYCS | cytochrome c, somatic | 2.25711 |
| CYB561 | cytochrome b561 | 2.18427 |
| DIPK1A | divergent protein kinase domain 1A | 2.16937 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.15153 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 2.12494 |
| DMBT1 | deleted in malignant brain tumors 1 | 2.08198 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.08001 |
| JADE2 | jade family PHD finger 2 | 2.07137 |
| IRF8 | interferon regulatory factor 8 | 2.05581 |
| S100A2 | S100 calcium binding protein A2 | 2.04568 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 2.03734 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | 2.02438 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 2.00552 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -8.09337 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -7.87013 |
| CD320 | CD320 molecule | -5.12801 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -5.1115 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.96959 |
| PCNA | proliferating cell nuclear antigen | -4.79753 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.63789 |
| PLK1 | polo-like kinase 1 | -4.50255 |
| DSG2 | desmoglein 2 | -3.71675 |
| TOR1A | torsin family 1, member A (torsin A) | -3.52231 |
| GOLT1B | golgi transport 1B | -3.51005 |
| CCNB2 | cyclin B2 | -3.43816 |
| DUSP6 | dual specificity phosphatase 6 | -3.29638 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.16546 |
| WASHC4 | WASH complex subunit 4 | -3.06655 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.03656 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.00422 |
| EGF | epidermal growth factor | -2.99245 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -2.9463 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -2.92117 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.91089 |
| TXNDC9 | thioredoxin domain containing 9 | -2.67888 |
| HEATR1 | HEAT repeat containing 1 | -2.58038 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -2.4564 |
| CSK | c-src tyrosine kinase | -2.3608 |
| MACF1 | microtubule-actin crosslinking factor 1 | -2.34586 |
| CHMP4B | charged multivesicular body protein 4B | -2.34132 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -2.28084 |
| NGRN | neugrin, neurite outgrowth associated | -2.23114 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.13144 |
| TCTN1 | tectonic family member 1 | -2.07612 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.03935 |
| ANKRD10 | ankyrin repeat domain 10 | -2.01444 |
| PINLYP | phospholipase A2 inhibitor and LY6/PLAUR domain containing | -2.00819 |
