CRCGN009_HEPG2_24H:K05 Gene Set
Genes
45 genes differentially expressed following the CRCGN009_HEPG2_24H:K05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
5.21448
|
|
SATB1
|
SATB homeobox 1
|
4.10687
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
4.01013
|
|
NOTCH1
|
notch 1
|
3.95922
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.84726
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.82736
|
|
MOK
|
MOK protein kinase
|
3.67507
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.54014
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.5261
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.48545
|
|
MYLK
|
myosin light chain kinase
|
3.43738
|
|
TRAM2
|
translocation associated membrane protein 2
|
3.03777
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.92156
|
|
RPL39L
|
ribosomal protein L39-like
|
2.56695
|
|
E2F2
|
E2F transcription factor 2
|
2.45649
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.29943
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.29245
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.25032
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.21816
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
2.17744
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.11675
|
|
PRR15L
|
proline rich 15-like
|
2.02327
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-5.51021
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-5.08808
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.34415
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.19247
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.34109
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.03517
|
|
CDC25B
|
cell division cycle 25B
|
-2.83346
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.8156
|
|
GOLT1B
|
golgi transport 1B
|
-2.65546
|
|
HMG20B
|
high mobility group 20B
|
-2.64686
|
|
EGF
|
epidermal growth factor
|
-2.62915
|
|
TLR4
|
toll-like receptor 4
|
-2.60937
|
|
SNX11
|
sorting nexin 11
|
-2.48649
|
|
ZNF586
|
zinc finger protein 586
|
-2.39902
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.39101
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.22097
|
|
CDKN2A
|
cyclin-dependent kinase inhibitor 2A
|
-2.17544
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-2.1668
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.15942
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.15472
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.13984
|
|
CCNB2
|
cyclin B2
|
-2.0367
|
|
RAI14
|
retinoic acid induced 14
|
-2.01954
|
