CRCGN009_HEPG2_24H:K06 Gene Set
Genes
41 genes differentially expressed following the CRCGN009_HEPG2_24H:K06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
10.0
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
7.52955
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
6.49681
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.78797
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.2946
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.17117
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
4.06193
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
4.05683
|
|
NOTCH1
|
notch 1
|
4.03657
|
|
BLMH
|
bleomycin hydrolase
|
3.75701
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.62633
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.54487
|
|
STIMATE
|
STIM activating enhancer
|
3.40316
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.39525
|
|
CBR3
|
carbonyl reductase 3
|
3.33238
|
|
HOXA10
|
homeobox A10
|
3.27169
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.47277
|
|
CHN1
|
chimerin 1
|
2.46508
|
|
EAPP
|
E2F-associated phosphoprotein
|
2.42754
|
|
JADE2
|
jade family PHD finger 2
|
2.31112
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.2218
|
|
DDX5
|
DEAD (Asp-Glu-Ala-Asp) box helicase 5
|
2.21719
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
2.16685
|
|
FAM111A
|
family with sequence similarity 111, member A
|
2.01216
|
|
RPL39L
|
ribosomal protein L39-like
|
2.0119
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-7.99042
|
|
LDHD
|
lactate dehydrogenase D
|
-5.88364
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.57994
|
|
GOLT1B
|
golgi transport 1B
|
-4.50021
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.27485
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-4.03319
|
|
CCNB1
|
cyclin B1
|
-3.77461
|
|
RAI14
|
retinoic acid induced 14
|
-3.42413
|
|
CCNB2
|
cyclin B2
|
-3.32576
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.02954
|
|
LSM6
|
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.95378
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.79154
|
|
CA2
|
carbonic anhydrase II
|
-2.1842
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.13821
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.07127
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.03902
|
