CRCGN009_HEPG2_24H:K09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vorinostat 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1366 genes differentially expressed following the CRCGN009_HEPG2_24H:K09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ALDOC aldolase C, fructose-bisphosphate 10.0
STX1A syntaxin 1A (brain) 10.0
DNM1 dynamin 1 10.0
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
TBC1D10C TBC1 domain family, member 10C 10.0
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 10.0
FOXO4 forkhead box O4 9.94691
ZDHHC6 zinc finger, DHHC-type containing 6 9.86202
PLA2G15 phospholipase A2, group XV 9.69355
LGMN legumain 9.41309
TAC4 tachykinin 4 (hemokinin) 9.19573
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 9.19563
CBR1 carbonyl reductase 1 8.99885
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 8.56168
STXBP1 syntaxin binding protein 1 8.3873
UBE2L6 ubiquitin-conjugating enzyme E2L 6 8.05098
H2BC12 H2B clustered histone 12 7.74548
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 7.47951
MCOLN1 mucolipin 1 7.39993
ZFP36 ZFP36 ring finger protein 7.37764
AMDHD2 amidohydrolase domain containing 2 7.2807
CARMIL1 capping protein regulator and myosin 1 linker 1 7.14238
LSR lipolysis stimulated lipoprotein receptor 7.12541
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 6.85323
CCND3 cyclin D3 6.73516
CORO1A coronin, actin binding protein, 1A 6.65689
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 6.53837
FCHO1 FCH domain only 1 6.45024
NIT1 nitrilase 1 6.35121
TMEM50A transmembrane protein 50A 6.31965
STIMATE STIM activating enhancer 6.29466
TBPL1 TBP-like 1 6.00132
PTPN1 protein tyrosine phosphatase, non-receptor type 1 5.97473
NR1H2 nuclear receptor subfamily 1, group H, member 2 5.9404
GET1 guided entry of tail-anchored proteins factor 1 5.87775
TMCO1 transmembrane and coiled-coil domains 1 5.74042
HLA-DMA major histocompatibility complex, class II, DM alpha 5.73504
H2BC21 H2B clustered histone 21 5.64153
INTS3 integrator complex subunit 3 5.56374
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 5.52693
TCEA2 transcription elongation factor A (SII), 2 5.448
NUCB2 nucleobindin 2 5.39717
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 5.38067
PPP1R13B protein phosphatase 1, regulatory subunit 13B 5.26243
COG7 component of oligomeric golgi complex 7 5.25494
DUSP6 dual specificity phosphatase 6 5.14775
EGR1 early growth response 1 5.14162
TERF2IP telomeric repeat binding factor 2, interacting protein 5.12307
SKIC2 SKI2 subunit of superkiller complex 5.11086
HSPA1A heat shock 70kDa protein 1A 5.1071
ARFIP2 ADP-ribosylation factor interacting protein 2 5.04481
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 4.99271
MALT1 MALT1 paracaspase 4.94036
CALM3 calmodulin 3 (phosphorylase kinase, delta) 4.89986
UBE3C ubiquitin protein ligase E3C 4.87932
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 4.83715
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 4.83559
MVP major vault protein 4.81981
COG2 component of oligomeric golgi complex 2 4.81732
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 4.81603
GTF2A2 general transcription factor IIA, 2, 12kDa 4.77306
RAB11FIP1 RAB11 family interacting protein 1 (class I) 4.74576
RSU1 Ras suppressor protein 1 4.74536
CYCS cytochrome c, somatic 4.74416
CAB39 calcium binding protein 39 4.72176
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 4.70292
HMOX1 heme oxygenase 1 4.6697
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 4.61666
NOTCH1 notch 1 4.55337
ABHD4 abhydrolase domain containing 4 4.5311
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 4.50535
BAMBI BMP and activin membrane-bound inhibitor 4.42392
SETD3 SET domain containing 3 4.38765
UNC93B1 unc-93 homolog B1 (C. elegans) 4.36943
CGRRF1 cell growth regulator with ring finger domain 1 4.36655
TRAPPC6A trafficking protein particle complex 6A 4.35758
TIMP2 TIMP metallopeptidase inhibitor 2 4.3317
PRKCD protein kinase C, delta 4.3303
SETD1A SET domain containing 1A 4.27644
GCDH glutaryl-CoA dehydrogenase 4.2488
CNPY4 canopy FGF signaling regulator 4 4.24664
ZNF646 zinc finger protein 646 4.24568
GOLGA7 golgin A7 4.23172
HDGFL3 HDGF like 3 4.23156
MNAT1 MNAT CDK-activating kinase assembly factor 1 4.21788
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 4.13463
IGFBP3 insulin-like growth factor binding protein 3 4.08263
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 4.07026
ATG2A autophagy related 2A 4.06649
CYTH1 cytohesin 1 4.03612
KCTD13 potassium channel tetramerization domain containing 13 4.01345
YPEL5 yippee-like 5 (Drosophila) 3.97559
KIF5C kinesin family member 5C 3.94093
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 3.94047
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 3.93509
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 3.90136
KDM3A lysine (K)-specific demethylase 3A 3.88759
MAPK3 mitogen-activated protein kinase 3 3.8585
H2BC5 H2B clustered histone 5 3.85232
SYNE2 spectrin repeat containing, nuclear envelope 2 3.83591
TXNL4B thioredoxin-like 4B 3.82243
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 3.80087
PHKG2 phosphorylase kinase, gamma 2 (testis) 3.79097
CLEC16A C-type lectin domain family 16, member A 3.78269
GSTP1 glutathione S-transferase pi 1 3.77985
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 3.76288
BBC3 BCL2 binding component 3 3.75179
CCNA1 cyclin A1 3.74341
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 3.73193
CCDC92 coiled-coil domain containing 92 3.7173
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 3.67997
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 3.66316
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.66277
BORCS6 BLOC-1 related complex subunit 6 3.66039
TCF15 transcription factor 15 (basic helix-loop-helix) 3.65867
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 3.64756
CTR9 CTR9, Paf1/RNA polymerase II complex component 3.6416
PPARD peroxisome proliferator-activated receptor delta 3.63447
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 3.63358
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 3.62574
LRP10 low density lipoprotein receptor-related protein 10 3.62427
BACE2 beta-site APP-cleaving enzyme 2 3.62144
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.61949
KHDC4 KH domain containing 4, pre-mRNA splicing factor 3.61735
TTLL3 tubulin tyrosine ligase-like family member 3 3.60757
CCDC71 coiled-coil domain containing 71 3.60741
RNF167 ring finger protein 167 3.59301
ACAD10 acyl-CoA dehydrogenase family, member 10 3.58865
MAN2B1 mannosidase, alpha, class 2B, member 1 3.58644
AAMDC adipogenesis associated, Mth938 domain containing 3.57892
MUC3B mucin 3B, cell surface associated 3.54073
SFTPB surfactant protein B 3.54043
PXMP4 peroxisomal membrane protein 4, 24kDa 3.51944
SH3BP1 SH3-domain binding protein 1 3.50946
JADE2 jade family PHD finger 2 3.5055
RTN2 reticulon 2 3.49985
ROGDI rogdi homolog (Drosophila) 3.48838
LSM1 LSM1, U6 small nuclear RNA associated 3.48814
CCDC28A coiled-coil domain containing 28A 3.48235
RAB3A RAB3A, member RAS oncogene family 3.47674
RBBP5 retinoblastoma binding protein 5 3.46191
GIPC1 GIPC PDZ domain containing family, member 1 3.45
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 3.439
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 3.43347
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 3.42653
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 3.42509
ZNF212 zinc finger protein 212 3.41765
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 3.41569
RBM6 RNA binding motif protein 6 3.40616
SLC12A9 solute carrier family 12, member 9 3.39757
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 3.3901
PHF1 PHD finger protein 1 3.38787
MLEC malectin 3.38748
BTG2 BTG family, member 2 3.37453
AARS1 alanyl-tRNA synthetase 1 3.3728
BBS4 Bardet-Biedl syndrome 4 3.36008
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 3.35958
RND1 Rho family GTPase 1 3.35133
DENND2D DENN/MADD domain containing 2D 3.35036
H2AC6 H2A clustered histone 6 3.34925
SHARPIN SHANK-associated RH domain interactor 3.34633
ELAVL3 ELAV like neuron-specific RNA binding protein 3 3.33773
SLC25A44 solute carrier family 25, member 44 3.33348
RBKS ribokinase 3.3307
PRR13 proline rich 13 3.31786
E2F2 E2F transcription factor 2 3.31118
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 3.30534
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.30342
ANO10 anoctamin 10 3.28229
TYW2 tRNA wybutosine-synthesizing protein 2 3.28187
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 3.27364
GPR162 G protein-coupled receptor 162 3.27318
FASTKD5 FAST kinase domains 5 3.26656
TLE6 transducin-like enhancer of split 6 3.25174
GOLGB1 golgin B1 3.23902
MKNK1 MAP kinase interacting serine/threonine kinase 1 3.2333
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.22334
TOP6BL TOP6B like initiator of meiotic double strand breaks 3.22288
HMG20B high mobility group 20B 3.2161
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 3.21014
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 3.20883
TREM2 triggering receptor expressed on myeloid cells 2 3.19732
TWF2 twinfilin actin binding protein 2 3.19455
FBXO2 F-box protein 2 3.19044
SDK2 sidekick cell adhesion molecule 2 3.17672
INTS8 integrator complex subunit 8 3.17177
PRUNE1 prune exopolyphosphatase 1 3.16421
DPH2 DPH2 homolog (S. cerevisiae) 3.16279
DHDDS dehydrodolichyl diphosphate synthase 3.16269
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 3.15695
GET3 guided entry of tail-anchored proteins factor 3, ATPase 3.15105
AKAP8 A kinase (PRKA) anchor protein 8 3.13732
PLCH2 phospholipase C, eta 2 3.13632
KIFBP kinesin family binding protein 3.13476
INTS5 integrator complex subunit 5 3.13446
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 3.1326
BIN3 bridging integrator 3 3.12613
ADGRL1 adhesion G protein-coupled receptor L1 3.12172
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 3.11029
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 3.10705
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 3.1032
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.09384
SATB1 SATB homeobox 1 3.08743
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 3.07621
FAM110D family with sequence similarity 110, member D 3.07087
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 3.06413
IQCC IQ motif containing C 3.0547
SIN3B SIN3 transcription regulator family member B 3.0481
AMN amnion associated transmembrane protein 3.03362
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 3.02778
SPEG SPEG complex locus 3.02374
SNAP29 synaptosomal-associated protein, 29kDa 3.01661
ARID5A AT rich interactive domain 5A (MRF1-like) 3.015
LCMT1 leucine carboxyl methyltransferase 1 2.9952
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.99463
FRS2 fibroblast growth factor receptor substrate 2 2.99185
STAT1 signal transducer and activator of transcription 1, 91kDa 2.98757
YJU2B YJU2 splicing factor homolog B 2.9851
TP53BP1 tumor protein p53 binding protein 1 2.98158
SEPHS2 selenophosphate synthetase 2 2.97871
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 2.9785
ACTR6 ARP6 actin-related protein 6 homolog (yeast) 2.97651
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 2.97644
H1-2 H1.2 linker histone, cluster member 2.97072
TTC1 tetratricopeptide repeat domain 1 2.96797
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.96309
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 2.95541
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 2.95065
ARL3 ADP-ribosylation factor-like 3 2.94796
FIG4 FIG4 phosphoinositide 5-phosphatase 2.94524
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 2.94329
ASTE1 asteroid homolog 1 (Drosophila) 2.94316
MAST3 microtubule associated serine/threonine kinase 3 2.93482
ICAM1 intercellular adhesion molecule 1 2.93308
CSRNP2 cysteine-serine-rich nuclear protein 2 2.93278
KDM5A lysine (K)-specific demethylase 5A 2.93025
RAB4A RAB4A, member RAS oncogene family 2.92929
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 2.92248
RASA4 RAS p21 protein activator 4 2.91681
CPM carboxypeptidase M 2.91539
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 2.91486
GPBP1L1 GC-rich promoter binding protein 1-like 1 2.91337
ZNF394 zinc finger protein 394 2.90277
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 2.89686
SF3B4 splicing factor 3b, subunit 4, 49kDa 2.89661
DZANK1 double zinc ribbon and ankyrin repeat domains 1 2.89573
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) 2.89395
AKAP8L A kinase (PRKA) anchor protein 8-like 2.89314
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.8927
TRAPPC14 trafficking protein particle complex subunit 14 2.89042
RSF1 remodeling and spacing factor 1 2.88718
FABP3 fatty acid binding protein 3, muscle and heart 2.88364
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.88011
TUBB2B tubulin, beta 2B class IIb 2.87644
SDF2 stromal cell-derived factor 2 2.87386
GABARAPL2 GABA(A) receptor-associated protein-like 2 2.87166
PLPPR2 phospholipid phosphatase related 2 2.86978
RMC1 regulator of MON1-CCZ1 2.86253
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 2.86172
TUSC2 tumor suppressor candidate 2 2.85727
UBE2W ubiquitin-conjugating enzyme E2W (putative) 2.85341
ASB6 ankyrin repeat and SOCS box containing 6 2.85053
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 2.84714
H2BC9 H2B clustered histone 9 2.84661
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 2.84582
AKIRIN1 akirin 1 2.84514
CLDN3 claudin 3 2.84008
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 2.83593
BCL7B B-cell CLL/lymphoma 7B 2.83262
MDFI MyoD family inhibitor 2.83261
HEXIM1 hexamethylene bis-acetamide inducible 1 2.8311
MYO9A myosin IXA 2.82973
SQSTM1 sequestosome 1 2.82925
WDR47 WD repeat domain 47 2.82624
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 2.82405
HINFP histone H4 transcription factor 2.82399
MAGEH1 melanoma antigen family H1 2.82102
H2BC4 H2B clustered histone 4 2.81604
DKKL1 dickkopf-like 1 2.80715
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.80234
ACBD4 acyl-CoA binding domain containing 4 2.80095
MAP7 microtubule-associated protein 7 2.79486
ZNF205 zinc finger protein 205 2.78992
RCE1 Ras converting CAAX endopeptidase 1 2.77877
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 2.7615
KIAA0319 KIAA0319 2.75935
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) 2.75846
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 2.75808
NME7 NME/NM23 family member 7 2.75803
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.75792
CELF3 CUGBP, Elav-like family member 3 2.75396
MTCH1 mitochondrial carrier 1 2.75216
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 2.74867
IFT27 intraflagellar transport 27 2.73928
ANKRD46 ankyrin repeat domain 46 2.73539
CLDN6 claudin 6 2.7343
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.73404
CFB complement factor B 2.73394
TMEM265 transmembrane protein 265 2.73057
MEF2D myocyte enhancer factor 2D 2.72885
CSNK1E casein kinase 1, epsilon 2.72873
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.72798
DDB2 damage-specific DNA binding protein 2, 48kDa 2.72406
ING1 inhibitor of growth family, member 1 2.72127
DYNC2I1 dynein 2 intermediate chain 1 2.71176
RIDA reactive intermediate imine deaminase A homolog 2.71009
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.70843
FOXO3 forkhead box O3 2.70629
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 2.70626
TSC22D4 TSC22 domain family, member 4 2.70406
ROM1 retinal outer segment membrane protein 1 2.70148
HDAC5 histone deacetylase 5 2.69341
MPHOSPH8 M-phase phosphoprotein 8 2.67966
NLGN3 neuroligin 3 2.67937
CALCOCO1 calcium binding and coiled-coil domain 1 2.67928
PPP4C protein phosphatase 4, catalytic subunit 2.67237
EDC3 enhancer of mRNA decapping 3 2.67133
EHMT2 euchromatic histone-lysine N-methyltransferase 2 2.67104
PLK3 polo-like kinase 3 2.66579
GLO1 glyoxalase I 2.66359
FKBPL FK506 binding protein like 2.66243
TSPYL2 TSPY-like 2 2.66114
ACOT13 acyl-CoA thioesterase 13 2.65786
MAPRE3 microtubule-associated protein, RP/EB family, member 3 2.65532
FBRS fibrosin 2.65334
MARCHF2 membrane associated ring-CH-type finger 2 2.6504
CRYZL1 crystallin, zeta (quinone reductase)-like 1 2.64895
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.64683
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 2.63669
GPR137B G protein-coupled receptor 137B 2.63569
KLF13 Kruppel-like factor 13 2.63343
WDR19 WD repeat domain 19 2.63043
ARF3 ADP-ribosylation factor 3 2.62951
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 2.62748
ATP10D ATPase, class V, type 10D 2.61622
MPPED2 metallophosphoesterase domain containing 2 2.61494
SIX1 SIX homeobox 1 2.61473
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 2.61236
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.61149
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 2.60758
DOC2A double C2-like domains, alpha 2.60428
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 2.60255
RBM12B RNA binding motif protein 12B 2.60241
CDC20 cell division cycle 20 2.59899
ZNF696 zinc finger protein 696 2.59259
AAGAB alpha- and gamma-adaptin binding protein 2.59164
CREB3L2 cAMP responsive element binding protein 3-like 2 2.5833
BPHL biphenyl hydrolase-like (serine hydrolase) 2.58326
CALM1 calmodulin 1 (phosphorylase kinase, delta) 2.58065
CPT2 carnitine palmitoyltransferase 2 2.57846
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 2.57736
AGER advanced glycosylation end product-specific receptor 2.56579
RAP1B RAP1B, member of RAS oncogene family 2.56409
HAND2 heart and neural crest derivatives expressed 2 2.56253
NCAPD2 non-SMC condensin I complex, subunit D2 2.56073
GADD45B growth arrest and DNA-damage-inducible, beta 2.55864
EPN2 epsin 2 2.55846
GM2A GM2 ganglioside activator 2.5559
CEP70 centrosomal protein 70kDa 2.55389
ACP5 acid phosphatase 5, tartrate resistant 2.55174
UBE2S ubiquitin-conjugating enzyme E2S 2.55035
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 2.54817
IRF7 interferon regulatory factor 7 2.54764
ETV6 ets variant 6 2.54395
DPF1 D4, zinc and double PHD fingers family 1 2.54252
KLHL26 kelch-like family member 26 2.54184
GRWD1 glutamate-rich WD repeat containing 1 2.54063
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.53975
ZBTB48 zinc finger and BTB domain containing 48 2.53931
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.53752
CMTR1 cap methyltransferase 1 2.5361
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 2.53517
BCAM basal cell adhesion molecule (Lutheran blood group) 2.53064
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.52747
SAP25 Sin3A-associated protein, 25kDa 2.52584
HOOK2 hook microtubule-tethering protein 2 2.52489
BAD BCL2-associated agonist of cell death 2.52485
EML1 echinoderm microtubule associated protein like 1 2.52254
PRR14 proline rich 14 2.52192
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.5217
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.52093
MSRB1 methionine sulfoxide reductase B1 2.51918
SH2B1 SH2B adaptor protein 1 2.51673
CYB561 cytochrome b561 2.50639
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 2.50611
NPDC1 neural proliferation, differentiation and control, 1 2.50322
NXPH4 neurexophilin 4 2.50207
TXNRD1 thioredoxin reductase 1 2.50165
OCEL1 occludin/ELL domain containing 1 2.5014
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 2.49915
PARP6 poly (ADP-ribose) polymerase family, member 6 2.49754
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 2.49587
BAZ2A bromodomain adjacent to zinc finger domain, 2A 2.48785
TRAFD1 TRAF-type zinc finger domain containing 1 2.48519
RHOT2 ras homolog family member T2 2.48213
PFKM phosphofructokinase, muscle 2.48071
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 2.4807
MLF2 myeloid leukemia factor 2 2.47993
DGAT1 diacylglycerol O-acyltransferase 1 2.47985
ASIC4 acid sensing (proton gated) ion channel family member 4 2.47746
CSNK1G1 casein kinase 1, gamma 1 2.47706
GNG7 guanine nucleotide binding protein (G protein), gamma 7 2.47688
CDK5 cyclin-dependent kinase 5 2.4746
CCL4 chemokine (C-C motif) ligand 4 2.47391
ABHD11 abhydrolase domain containing 11 2.47113
EFNA3 ephrin-A3 2.47047
ZMIZ2 zinc finger, MIZ-type containing 2 2.46992
PAOX polyamine oxidase (exo-N4-amino) 2.46567
UBE2H ubiquitin-conjugating enzyme E2H 2.46436
TSEN34 TSEN34 tRNA splicing endonuclease subunit 2.46343
LMAN2L lectin, mannose-binding 2-like 2.46081
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 2.45867
ZFC3H1 zinc finger, C3H1-type containing 2.45756
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 2.45487
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 2.4514
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 2.44857
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 2.44796
IGF1R insulin-like growth factor 1 receptor 2.43995
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 2.43739
CD9 CD9 molecule 2.43718
SFRP4 secreted frizzled-related protein 4 2.43404
PAIP2B poly(A) binding protein interacting protein 2B 2.4321
PGAP6 post-GPI attachment to proteins 6 2.43196
TRIM62 tripartite motif containing 62 2.43109
TRPM8 transient receptor potential cation channel, subfamily M, member 8 2.43028
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 2.42709
MLF1 myeloid leukemia factor 1 2.42407
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 2.42033
GPN3 GPN-loop GTPase 3 2.42026
ZNF34 zinc finger protein 34 2.41951
SALL2 spalt-like transcription factor 2 2.41735
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.41588
TUBG2 tubulin, gamma 2 2.41421
ZCCHC14 zinc finger, CCHC domain containing 14 2.41372
ARHGAP33 Rho GTPase activating protein 33 2.41337
PRX periaxin 2.41197
GIPR gastric inhibitory polypeptide receptor 2.40858
UBN1 ubinuclein 1 2.40829
MED13L mediator complex subunit 13-like 2.40715
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.40591
BLCAP bladder cancer associated protein 2.40505
OPLAH 5-oxoprolinase (ATP-hydrolysing) 2.40417
NUP133 nucleoporin 133kDa 2.40368
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 2.40316
IQGAP1 IQ motif containing GTPase activating protein 1 2.40002
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 2.39944
ADGRD2 adhesion G protein-coupled receptor D2 2.39648
LEMD3 LEM domain containing 3 2.39491
PPY pancreatic polypeptide 2.39328
GSTM2 glutathione S-transferase mu 2 (muscle) 2.39235
PRPF18 pre-mRNA processing factor 18 2.39172
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 2.39068
ZNG1A Zn regulated GTPase metalloprotein activator 1A 2.39051
ZFTRAF1 zinc finger TRAF-type containing 1 2.39001
SAP30L SAP30-like 2.38986
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 2.3879
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 2.38775
RUSF1 RUS family member 1 2.38558
EBNA1BP2 EBNA1 binding protein 2 2.38556
ARHGAP25 Rho GTPase activating protein 25 2.38317
MXI1 MAX interactor 1, dimerization protein 2.38259
VAT1 vesicle amine transport 1 2.38134
ACTR5 ARP5 actin-related protein 5 homolog (yeast) 2.37904
FXYD7 FXYD domain containing ion transport regulator 7 2.37728
TGM1 transglutaminase 1 2.37537
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 2.37533
LIAS lipoic acid synthetase 2.37506
FURIN furin (paired basic amino acid cleaving enzyme) 2.37443
OSTF1 osteoclast stimulating factor 1 2.36839
NPR1 natriuretic peptide receptor 1 2.36799
IRF3 interferon regulatory factor 3 2.36481
MYF5 myogenic factor 5 2.36308
CATSPER2 cation channel, sperm associated 2 2.35824
FOXC1 forkhead box C1 2.35699
BCKDK branched chain ketoacid dehydrogenase kinase 2.35605
FGD6 FYVE, RhoGEF and PH domain containing 6 2.35547
TNNT1 troponin T type 1 (skeletal, slow) 2.35335
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.35186
CTBP2 C-terminal binding protein 2 2.34956
BCAS4 breast carcinoma amplified sequence 4 2.34917
ERI3 ERI1 exoribonuclease family member 3 2.34714
CREG1 cellular repressor of E1A-stimulated genes 1 2.34672
BAZ1B bromodomain adjacent to zinc finger domain, 1B 2.34283
EVX1 even-skipped homeobox 1 2.34244
CIB2 calcium and integrin binding family member 2 2.3362
SPATS2 spermatogenesis associated, serine-rich 2 2.33165
CRX cone-rod homeobox 2.33139
SSH3 slingshot protein phosphatase 3 2.32931
LDHD lactate dehydrogenase D 2.32778
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 2.32677
ZMYM1 zinc finger, MYM-type 1 2.32516
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 2.32468
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 2.32439
TM7SF2 transmembrane 7 superfamily member 2 2.32371
HDAC7 histone deacetylase 7 2.32328
S100A14 S100 calcium binding protein A14 2.32292
DUX4 double homeobox 4 2.32231
CLIC5 chloride intracellular channel 5 2.32154
HPSE heparanase 2.31991
RAB21 RAB21, member RAS oncogene family 2.3197
CLSTN3 calsyntenin 3 2.31842
ADIPOR1 adiponectin receptor 1 2.3145
MRNIP MRN complex interacting protein 2.31355
TPMT thiopurine S-methyltransferase 2.31233
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 2.31169
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 2.31044
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 2.31018
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 2.31
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 2.30953
FBXO46 F-box protein 46 2.30895
TMEM255A transmembrane protein 255A 2.30764
KLF7 Kruppel-like factor 7 (ubiquitous) 2.30679
TSPYL5 TSPY-like 5 2.30521
OXCT2 3-oxoacid CoA transferase 2 2.30406
ARMCX2 armadillo repeat containing, X-linked 2 2.30261
TUBA4A tubulin, alpha 4a 2.3024
STXBP2 syntaxin binding protein 2 2.29991
RASL12 RAS-like, family 12 2.28986
ACOT8 acyl-CoA thioesterase 8 2.28964
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 2.28858
WDR44 WD repeat domain 44 2.28837
RIC8A RIC8 guanine nucleotide exchange factor A 2.28834
RB1CC1 RB1-inducible coiled-coil 1 2.28831
KANK3 KN motif and ankyrin repeat domains 3 2.28793
ADRB2 adrenoceptor beta 2, surface 2.2863
NPIPA6 nuclear pore complex interacting protein family, member A6 2.28328
ZNF14 zinc finger protein 14 2.28146
EMD emerin 2.27761
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 2.27746
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 2.27362
STX5 syntaxin 5 2.27283
PDCD6 programmed cell death 6 2.27152
PPP1R16B protein phosphatase 1, regulatory subunit 16B 2.27144
FBXL15 F-box and leucine-rich repeat protein 15 2.27108
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 2.26954
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.26718
RUNDC3A RUN domain containing 3A 2.26709
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 2.2667
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 2.26667
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 2.26411
VAMP7 vesicle-associated membrane protein 7 2.26338
CD81 CD81 molecule 2.2622
SMTN smoothelin 2.26172
SIRT3 sirtuin 3 2.25726
RASA4B RAS p21 protein activator 4B 2.25615
OSGIN1 oxidative stress induced growth inhibitor 1 2.25585
AAMP angio-associated, migratory cell protein 2.25405
NDNF neuron-derived neurotrophic factor 2.25019
WIPF2 WAS/WASL interacting protein family, member 2 2.24994
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 2.24926
CTF1 cardiotrophin 1 2.24893
DYNLT1 dynein, light chain, Tctex-type 1 2.24834
SLC46A3 solute carrier family 46, member 3 2.24777
TDP2 tyrosyl-DNA phosphodiesterase 2 2.24738
SNX3 sorting nexin 3 2.24715
TESK1 testis-specific kinase 1 2.24675
PTP4A3 protein tyrosine phosphatase type IVA, member 3 2.2449
GATA2 GATA binding protein 2 2.24459
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 2.2442
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.24304
PGPEP1 pyroglutamyl-peptidase I 2.24249
RAB17 RAB17, member RAS oncogene family 2.24169
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 2.24146
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 2.24073
CBX4 chromobox homolog 4 2.23784
FUZ fuzzy planar cell polarity protein 2.23607
TRAPPC3 trafficking protein particle complex 3 2.23519
CRABP2 cellular retinoic acid binding protein 2 2.23256
SH3GL3 SH3-domain GRB2-like 3 2.23254
TMEM41B transmembrane protein 41B 2.23158
ARL4C ADP-ribosylation factor-like 4C 2.2309
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 2.22911
SPI1 Spi-1 proto-oncogene 2.2277
CATSPERH catsper channel auxiliary subunit eta 2.22398
ZBP1 Z-DNA binding protein 1 2.22134
CCS copper chaperone for superoxide dismutase 2.22054
EFHC1 EF-hand domain (C-terminal) containing 1 2.21619
OGA O-GlcNAcase 2.21491
BBS9 Bardet-Biedl syndrome 9 2.21284
SNIP1 Smad nuclear interacting protein 1 2.20862
IFT57 intraflagellar transport 57 2.20411
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 2.20397
LDB2 LIM domain binding 2 2.20362
PODXL podocalyxin-like 2.20208
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 2.20177
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 2.19515
MARF1 meiosis regulator and mRNA stability factor 1 2.19477
ORC4 origin recognition complex, subunit 4 2.19349
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 2.19302
PIAS3 protein inhibitor of activated STAT, 3 2.19258
CBX7 chromobox homolog 7 2.19189
ADRA2C adrenoceptor alpha 2C 2.18885
NCOA3 nuclear receptor coactivator 3 2.17821
ZNF277 zinc finger protein 277 2.1773
ELMO3 engulfment and cell motility 3 2.17352
MGST3 microsomal glutathione S-transferase 3 2.17284
HESX1 HESX homeobox 1 2.17064
ATF7IP2 activating transcription factor 7 interacting protein 2 2.1689
TBX4 T-box 4 2.16472
FAM200C family with sequence similarity 200 member C 2.16414
DTX2 deltex 2, E3 ubiquitin ligase 2.16065
MBD1 methyl-CpG binding domain protein 1 2.15776
TMEM121 transmembrane protein 121 2.15697
ARMC6 armadillo repeat containing 6 2.15681
USB1 U6 snRNA biogenesis 1 2.15633
SIRT7 sirtuin 7 2.15603
ARC activity-regulated cytoskeleton-associated protein 2.15411
UBL5 ubiquitin-like 5 2.15348
DRC11 dynein regulatory complex subunit 11 2.15216
BAIAP3 BAI1-associated protein 3 2.15072
DNM2 dynamin 2 2.1506
SPATA2 spermatogenesis associated 2 2.1501
TPPP tubulin polymerization promoting protein 2.14846
KLF10 Kruppel-like factor 10 2.14803
METTL25B methyltransferase like 25B 2.14716
HLA-E major histocompatibility complex, class I, E 2.14684
KL klotho 2.14652
TECR trans-2,3-enoyl-CoA reductase 2.14449
MTERF4 mitochondrial transcription termination factor 4 2.14425
EZR ezrin 2.14387
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 2.14301
MRPS22 mitochondrial ribosomal protein S22 2.14132
BBS10 Bardet-Biedl syndrome 10 2.14118
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 2.14047
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.13524
H2AC25 H2A clustered histone 25 2.13471
MAGEB2 melanoma antigen family B2 2.13112
PCDH1 protocadherin 1 2.13064
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 2.12834
PRAF2 PRA1 domain family, member 2 2.12726
AP1B1 adaptor-related protein complex 1, beta 1 subunit 2.12682
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 2.12553
PIAS1 protein inhibitor of activated STAT, 1 2.12544
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 2.12411
REEP2 receptor accessory protein 2 2.12374
APEH acylaminoacyl-peptide hydrolase 2.12366
LUZP1 leucine zipper protein 1 2.12299
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 2.12075
UQCRH ubiquinol-cytochrome c reductase hinge protein 2.11949
CCL3L3 chemokine (C-C motif) ligand 3-like 3 2.11913
ITGA7 integrin, alpha 7 2.11768
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 2.11677
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 2.11634
TESK2 testis-specific kinase 2 2.1163
THSD7A thrombospondin, type I, domain containing 7A 2.11582
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 2.11287
WDCP WD repeat and coiled coil containing 2.1106
WIPI2 WD repeat domain, phosphoinositide interacting 2 2.10835
TMEM35A transmembrane protein 35A 2.10799
NCOR2 nuclear receptor corepressor 2 2.10692
CEP290 centrosomal protein 290kDa 2.10616
HPCA hippocalcin 2.10589
IL18BP interleukin 18 binding protein 2.10567
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 2.10539
ZNF7 zinc finger protein 7 2.10423
NSD1 nuclear receptor binding SET domain protein 1 2.10421
IER2 immediate early response 2 2.10313
CNTN1 contactin 1 2.10304
ASCL1 achaete-scute family bHLH transcription factor 1 2.10302
AHDC1 AT hook, DNA binding motif, containing 1 2.10147
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.10068
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 2.09898
ZBTB22 zinc finger and BTB domain containing 22 2.09766
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 2.09705
BTN3A1 butyrophilin, subfamily 3, member A1 2.09631
MYL10 myosin, light chain 10, regulatory 2.09527
GSDMB gasdermin B 2.09506
ISCU iron-sulfur cluster assembly enzyme 2.09358
U2AF2 U2 small nuclear RNA auxiliary factor 2 2.09301
ITM2C integral membrane protein 2C 2.09301
UNC119 unc-119 homolog (C. elegans) 2.08831
KIAA0040 KIAA0040 2.0849
TAOK2 TAO kinase 2 2.08293
USP8 ubiquitin specific peptidase 8 2.08275
TRIM11 tripartite motif containing 11 2.08209
IFI27 interferon, alpha-inducible protein 27 2.08066
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 2.07889
YIPF2 Yip1 domain family, member 2 2.07855
GRB2 growth factor receptor-bound protein 2 2.07836
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 2.0777
GHR growth hormone receptor 2.07746
MMUT methylmalonyl-CoA mutase 2.07717
PIGH phosphatidylinositol glycan anchor biosynthesis, class H 2.07341
ALX3 ALX homeobox 3 2.07281
QRICH1 glutamine-rich 1 2.07224
DMPK dystrophia myotonica-protein kinase 2.06915
CISD1 CDGSH iron sulfur domain 1 2.06858
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 2.06803
RSRP1 arginine/serine-rich protein 1 2.06611
NFS1 NFS1 cysteine desulfurase 2.06555
RUBCN rubicon autophagy regulator 2.0649
SMIM44 small integral membrane protein 44 2.06247
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.06227
PNRC1 proline-rich nuclear receptor coactivator 1 2.0607
ZNF324 zinc finger protein 324 2.05928
SACK1E scaffolding CK1 anchoring protein E 2.05605
ERCC2 excision repair cross-complementation group 2 2.05412
SYNDIG1 synapse differentiation inducing 1 2.05343
NTAN1 N-terminal asparagine amidase 2.05331
UNC13A unc-13 homolog A (C. elegans) 2.05305
PICK1 protein interacting with PRKCA 1 2.05196
HELZ helicase with zinc finger 2.05062
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 2.04847
CARD10 caspase recruitment domain family, member 10 2.04757
GPD1L glycerol-3-phosphate dehydrogenase 1-like 2.0472
FUCA1 fucosidase, alpha-L- 1, tissue 2.04626
GMPPA GDP-mannose pyrophosphorylase A 2.04605
TDRD7 tudor domain containing 7 2.04462
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 2.04451
KCTD17 potassium channel tetramerization domain containing 17 2.04275
ZNF195 zinc finger protein 195 2.04154
METTL2A methyltransferase like 2A 2.04085
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 2.03981
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 2.03894
FAM168A family with sequence similarity 168, member A 2.03604
RARA retinoic acid receptor, alpha 2.0354
IFT20 intraflagellar transport 20 2.03426
USP20 ubiquitin specific peptidase 20 2.03349
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2.0303
DSE dermatan sulfate epimerase 2.03027
ZNF574 zinc finger protein 574 2.02855
C2CD3 C2 calcium-dependent domain containing 3 2.02854
ZNF623 zinc finger protein 623 2.02844
CLBA1 clathrin binding box of aftiphilin containing 1 2.02754
AASS aminoadipate-semialdehyde synthase 2.02636
CLPTM1 cleft lip and palate associated transmembrane protein 1 2.0262
SCARB1 scavenger receptor class B, member 1 2.02392
GPR20 G protein-coupled receptor 20 2.02237
GDE1 glycerophosphodiester phosphodiesterase 1 2.0213
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 2.02063
WDR5B WD repeat domain 5B 2.01997
KIF3A kinesin family member 3A 2.01979
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.01827
STYXL1 serine/threonine/tyrosine interacting-like 1 2.01696
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 2.01604
FOLR3 folate receptor 3 (gamma) 2.01596
NOSIP nitric oxide synthase interacting protein 2.01558
ZC3H15 zinc finger CCCH-type containing 15 2.01406
TBXA2R thromboxane A2 receptor 2.01331
PRKCQ protein kinase C, theta 2.0126
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.01237
RYBP RING1 and YY1 binding protein 2.01007
ZBTB7B zinc finger and BTB domain containing 7B 2.00962
NPIPB6 nuclear pore complex interacting protein family, member B6 2.0089
LRRC42 leucine rich repeat containing 42 2.00708
DOK3 docking protein 3 2.00661
TCEAL2 transcription elongation factor A (SII)-like 2 2.00357
ZKSCAN2 zinc finger with KRAB and SCAN domains 2 2.00193
TPST2 tyrosylprotein sulfotransferase 2 2.00131

decreased expression

Symbol Name Standardized Value
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -10.0
RPIA ribose 5-phosphate isomerase A -10.0
ADI1 acireductone dioxygenase 1 -10.0
HMGA2 high mobility group AT-hook 2 -10.0
TRIB3 tribbles pseudokinase 3 -10.0
CCDC86 coiled-coil domain containing 86 -9.70485
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -9.09303
KEAP1 kelch-like ECH-associated protein 1 -8.98947
TLCD3A TLC domain containing 3A -8.94472
TCERG1 transcription elongation regulator 1 -8.92615
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -8.9003
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -8.78885
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -8.44834
STAP2 signal transducing adaptor family member 2 -8.30147
TLR4 toll-like receptor 4 -8.25812
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -8.19287
PGM1 phosphoglucomutase 1 -8.15177
SLC35F2 solute carrier family 35, member F2 -7.94726
ETFB electron-transfer-flavoprotein, beta polypeptide -7.8834
GLOD4 glyoxalase domain containing 4 -7.80871
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -7.77494
RRAGA Ras-related GTP binding A -7.71419
CCNA2 cyclin A2 -7.5315
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -7.46688
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -7.44704
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -7.41077
PCNA proliferating cell nuclear antigen -7.01497
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -6.98854
DSG2 desmoglein 2 -6.96237
TATDN2 TatD DNase domain containing 2 -6.92599
SCCPDH saccharopine dehydrogenase (putative) -6.87328
LOC124907782 dual specificity protein phosphatase 22 -6.81959
CRYZ crystallin, zeta (quinone reductase) -6.65521
PCCB propionyl CoA carboxylase, beta polypeptide -6.6216
MRPS2 mitochondrial ribosomal protein S2 -6.55726
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -6.55583
FAIM Fas apoptotic inhibitory molecule -6.4781
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -6.44594
DCTD dCMP deaminase -6.41765
TMEM109 transmembrane protein 109 -6.39207
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -6.28188
CHEK1 checkpoint kinase 1 -6.2804
PLK1 polo-like kinase 1 -6.2072
MAPK13 mitogen-activated protein kinase 13 -6.18225
TCTN1 tectonic family member 1 -6.17119
SPAG7 sperm associated antigen 7 -6.12339
PROS1 protein S (alpha) -6.08651
CD320 CD320 molecule -6.02136
CDK1 cyclin-dependent kinase 1 -6.01836
CDK4 cyclin-dependent kinase 4 -5.98344
TSPAN4 tetraspanin 4 -5.93295
HEATR1 HEAT repeat containing 1 -5.92291
ITFG1 integrin alpha FG-GAP repeat containing 1 -5.78577
ITGB5 integrin, beta 5 -5.70475
ISOC1 isochorismatase domain containing 1 -5.67509
LRRC41 leucine rich repeat containing 41 -5.67065
NUP85 nucleoporin 85kDa -5.66862
ZW10 zw10 kinetochore protein -5.60768
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -5.59072
SQOR sulfide quinone oxidoreductase -5.5808
FOSL1 FOS-like antigen 1 -5.51713
DCK deoxycytidine kinase -5.47905
GTPBP8 GTP-binding protein 8 (putative) -5.44013
ECH1 enoyl CoA hydratase 1, peroxisomal -5.37051
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -5.28018
TMEM97 transmembrane protein 97 -5.23664
SOAT2 sterol O-acyltransferase 2 -5.22669
VDAC1 voltage-dependent anion channel 1 -5.08419
NNT nicotinamide nucleotide transhydrogenase -5.08181
PHF2 PHD finger protein 2 -5.01611
LAP3 leucine aminopeptidase 3 -4.97033
UBE2C ubiquitin-conjugating enzyme E2C -4.96984
ASGR2 asialoglycoprotein receptor 2 -4.94774
CASP7 caspase 7, apoptosis-related cysteine peptidase -4.83738
ACOT9 acyl-CoA thioesterase 9 -4.7738
RAP1GAP RAP1 GTPase activating protein -4.74941
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.73774
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.71604
MRPS16 mitochondrial ribosomal protein S16 -4.70583
ERBB2 erb-b2 receptor tyrosine kinase 2 -4.67239
GTPBP6 GTP binding protein 6 (putative) -4.66672
AURKB aurora kinase B -4.65268
CCNB1 cyclin B1 -4.61861
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.59502
MRPL12 mitochondrial ribosomal protein L12 -4.54087
FXN frataxin -4.49089
MELK maternal embryonic leucine zipper kinase -4.49022
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -4.45011
ENOPH1 enolase-phosphatase 1 -4.44679
MICALL1 MICAL-like 1 -4.43986
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -4.38806
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -4.36659
HEBP1 heme binding protein 1 -4.34479
ACOT2 acyl-CoA thioesterase 2 -4.27468
FBXO7 F-box protein 7 -4.27175
SENP6 SUMO1/sentrin specific peptidase 6 -4.19091
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.15374
PUF60 poly-U binding splicing factor 60KDa -4.12367
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -4.10638
DERA deoxyribose-phosphate aldolase (putative) -4.08931
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -4.08874
MYLK myosin light chain kinase -4.0388
B4GAT1 beta-1,4-glucuronyltransferase 1 -4.02858
IGFBP1 insulin-like growth factor binding protein 1 -3.98553
USP22 ubiquitin specific peptidase 22 -3.97449
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -3.91006
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -3.90515
SYPL1 synaptophysin-like 1 -3.89325
KIF11 kinesin family member 11 -3.86276
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -3.86174
NCK2 NCK adaptor protein 2 -3.85771
TSPAN6 tetraspanin 6 -3.83948
TIMCC TIM double twin CX3C motif chaperone -3.83567
EXOSC8 exosome component 8 -3.83449
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -3.83394
CRELD2 cysteine-rich with EGF-like domains 2 -3.81837
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -3.8139
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -3.80494
TPM1 tropomyosin 1 (alpha) -3.78364
ANXA7 annexin A7 -3.77585
GNPDA1 glucosamine-6-phosphate deaminase 1 -3.73107
SEC23A Sec23 homolog A (S. cerevisiae) -3.72162
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -3.71063
NUP88 nucleoporin 88kDa -3.70895
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -3.69311
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -3.6897
LMNB1 lamin B1 -3.65117
NR2F6 nuclear receptor subfamily 2, group F, member 6 -3.64309
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -3.64118
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -3.62736
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -3.62694
CDC25A cell division cycle 25A -3.58658
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -3.5727
HSPD1 heat shock 60kDa protein 1 (chaperonin) -3.5612
TM9SF3 transmembrane 9 superfamily member 3 -3.55489
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -3.54817
F5 coagulation factor V (proaccelerin, labile factor) -3.51871
TFDP1 transcription factor Dp-1 -3.50346
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.49129
CRTAP cartilage associated protein -3.48906
AHSG alpha-2-HS-glycoprotein -3.46321
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -3.45419
MORC4 MORC family CW-type zinc finger 4 -3.45048
ELOVL6 ELOVL fatty acid elongase 6 -3.44947
RBFA ribosome binding factor A (putative) -3.44721
ORM2 orosomucoid 2 -3.42486
KANK1 KN motif and ankyrin repeat domains 1 -3.42089
ZBED1 zinc finger, BED-type containing 1 -3.41913
ERBB3 erb-b2 receptor tyrosine kinase 3 -3.41855
ATF5 activating transcription factor 5 -3.41627
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.40505
CPNE2 copine II -3.40149
TTLL12 tubulin tyrosine ligase-like family member 12 -3.37955
SOX4 SRY (sex determining region Y)-box 4 -3.37212
FAM216A family with sequence similarity 216, member A -3.35862
KLHL21 kelch-like family member 21 -3.34033
MANEA mannosidase, endo-alpha -3.3232
SPAG4 sperm associated antigen 4 -3.32041
FOXM1 forkhead box M1 -3.31106
PSAT1 phosphoserine aminotransferase 1 -3.27863
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -3.27389
AGA aspartylglucosaminidase -3.2705
IL4R interleukin 4 receptor -3.26722
SCRN1 secernin 1 -3.24577
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -3.24501
RIOX2 ribosomal oxygenase 2 -3.24211
ICAM3 intercellular adhesion molecule 3 -3.23372
AMBP alpha-1-microglobulin/bikunin precursor -3.23258
ANKRD44 ankyrin repeat domain 44 -3.22725
DEPDC1 DEP domain containing 1 -3.21956
CA9 carbonic anhydrase IX -3.21453
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 -3.21206
CNPY3 canopy FGF signaling regulator 3 -3.21152
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -3.19592
THOC1 THO complex 1 -3.18133
SPRY2 sprouty homolog 2 (Drosophila) -3.16966
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.15899
BIRC2 baculoviral IAP repeat containing 2 -3.1537
DUSP3 dual specificity phosphatase 3 -3.15228
IDE insulin-degrading enzyme -3.14817
NCSTN nicastrin -3.14815
INHBE inhibin, beta E -3.1331
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -3.13238
DAZAP1 DAZ associated protein 1 -3.12245
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 -3.11979
HADH hydroxyacyl-CoA dehydrogenase -3.1184
GBE1 glucan (1,4-alpha-), branching enzyme 1 -3.10982
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -3.10084
ZWINT ZW10 interacting kinetochore protein -3.09716
SLC35B1 solute carrier family 35, member B1 -3.09284
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.07981
SKA1 spindle and kinetochore associated complex subunit 1 -3.0715
APOA2 apolipoprotein A-II -3.07095
OGFRL1 opioid growth factor receptor-like 1 -3.06976
GAR1 GAR1 ribonucleoprotein -3.055
TOR1A torsin family 1, member A (torsin A) -3.04481
MRPL19 mitochondrial ribosomal protein L19 -3.03792
MZT2A mitotic spindle organizing protein 2A -3.03736
MTARC1 mitochondrial amidoxime reducing component 1 -3.03527
RCC1L RCC1 like -3.03381
SARS2 seryl-tRNA synthetase 2, mitochondrial -3.03235
ASGR1 asialoglycoprotein receptor 1 -3.03062
APOBEC3A_B APOBEC3A and APOBEC3B deletion hybrid -3.02347
PMF1-BGLAP PMF1-BGLAP readthrough -3.00296
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -3.00146
SPATA20 spermatogenesis associated 20 -3.00005
CHD1L chromodomain helicase DNA binding protein 1-like -2.99813
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -2.99227
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -2.99102
GALE UDP-galactose-4-epimerase -2.98592
RFC3 replication factor C (activator 1) 3, 38kDa -2.98511
MTMR2 myotubularin related protein 2 -2.98482
CAAP1 caspase activity and apoptosis inhibitor 1 -2.98125
QTRT1 queuine tRNA-ribosyltransferase 1 -2.97884
ARL2BP ADP-ribosylation factor-like 2 binding protein -2.97227
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -2.96573
HJURP Holliday junction recognition protein -2.96233
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.96222
APOB apolipoprotein B -2.96117
EXT1 exostosin glycosyltransferase 1 -2.95748
SPC25 SPC25, NDC80 kinetochore complex component -2.94861
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.94545
MYDGF myeloid-derived growth factor -2.94234
IPO5 importin 5 -2.93483
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.90886
KIF4A kinesin family member 4A -2.90611
ALCAM activated leukocyte cell adhesion molecule -2.90219
KIF15 kinesin family member 15 -2.89948
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.88492
UBA2 ubiquitin-like modifier activating enzyme 2 -2.88183
FGFR4 fibroblast growth factor receptor 4 -2.86982
TCEAL4 transcription elongation factor A (SII)-like 4 -2.86083
GTSE1 G-2 and S-phase expressed 1 -2.84443
ECPAS Ecm29 proteasome adaptor and scaffold -2.83862
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.83832
SOX5 SRY (sex determining region Y)-box 5 -2.83642
PGAM4 phosphoglycerate mutase family member 4 -2.8264
FEN1 flap structure-specific endonuclease 1 -2.82256
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -2.82175
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.81978
MYO19 myosin XIX -2.81271
TET3 tet methylcytosine dioxygenase 3 -2.81006
NUP62 nucleoporin 62kDa -2.80502
MLH1 mutL homolog 1 -2.804
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.78957
A1CF APOBEC1 complementation factor -2.78618
CASC3 cancer susceptibility candidate 3 -2.78279
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.7786
ADSL adenylosuccinate lyase -2.77192
CTDNEP1 CTD nuclear envelope phosphatase 1 -2.77088
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.76821
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 -2.7612
UBXN8 UBX domain protein 8 -2.75895
ADSS2 adenylosuccinate synthase 2 -2.75727
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.75424
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.74842
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -2.74841
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like -2.7469
MGST2 microsomal glutathione S-transferase 2 -2.74
DCPS decapping enzyme, scavenger -2.73933
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 -2.72278
SPTAN1 spectrin, alpha, non-erythrocytic 1 -2.72157
MYL5 myosin, light chain 5, regulatory -2.72093
WEE1 WEE1 G2 checkpoint kinase -2.71995
ZMYND11 zinc finger, MYND-type containing 11 -2.71925
AURKA aurora kinase A -2.7185
PHC2 polyhomeotic homolog 2 (Drosophila) -2.71826
NEK3 NIMA-related kinase 3 -2.71652
DKK1 dickkopf WNT signaling pathway inhibitor 1 -2.71634
SSUH2 ssu-2 homolog (C. elegans) -2.69756
PXMP2 peroxisomal membrane protein 2, 22kDa -2.69707
WDR12 WD repeat domain 12 -2.69449
TEAD4 TEA domain family member 4 -2.6913
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.69072
TIMELESS timeless circadian clock -2.68823
ENOSF1 enolase superfamily member 1 -2.68798
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -2.68701
MXRA8 matrix-remodelling associated 8 -2.68671
IFRD2 interferon-related developmental regulator 2 -2.68099
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -2.68085
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.67292
NPC1L1 NPC1-like 1 -2.66752
NSD2 nuclear receptor binding SET domain protein 2 -2.66517
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.66477
TERT telomerase reverse transcriptase -2.66232
SH2D4A SH2 domain containing 4A -2.66188
SMC4 structural maintenance of chromosomes 4 -2.66095
PTS 6-pyruvoyltetrahydropterin synthase -2.65904
IRAK3 interleukin-1 receptor-associated kinase 3 -2.65853
CST3 cystatin C -2.65759
POLK polymerase (DNA directed) kappa -2.65185
TXLNA taxilin alpha -2.65118
TICAM1 toll-like receptor adaptor molecule 1 -2.64763
RHOBTB1 Rho-related BTB domain containing 1 -2.64404
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -2.6419
FOXE1 forkhead box E1 -2.63857
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.63695
KYAT3 kynurenine aminotransferase 3 -2.63455
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -2.63307
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -2.62514
CDC73 cell division cycle 73 -2.62388
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) -2.61881
MBL2 mannose-binding lectin (protein C) 2, soluble -2.61467
CPB2 carboxypeptidase B2 (plasma) -2.61138
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.60674
HYOU1 hypoxia up-regulated 1 -2.60405
IARS1 isoleucyl-tRNA synthetase 1 -2.60343
SMN2 survival of motor neuron 2, centromeric -2.60255
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 -2.59751
C2CD2 C2 calcium-dependent domain containing 2 -2.59259
SRC SRC proto-oncogene, non-receptor tyrosine kinase -2.58776
TP53 tumor protein p53 -2.58675
RBX1 ring-box 1, E3 ubiquitin protein ligase -2.5847
ATXN10 ataxin 10 -2.58371
LRRC61 leucine rich repeat containing 61 -2.57549
PFKL phosphofructokinase, liver -2.57369
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -2.56943
NUP54 nucleoporin 54kDa -2.56146
STEAP3 STEAP family member 3, metalloreductase -2.55864
MOSPD2 motile sperm domain containing 2 -2.55778
SGSH N-sulfoglucosamine sulfohydrolase -2.55493
PHKA1 phosphorylase kinase, alpha 1 (muscle) -2.55436
TTR transthyretin -2.5508
BARD1 BRCA1 associated RING domain 1 -2.54989
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -2.54954
PRDX4 peroxiredoxin 4 -2.54953
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.54789
PLK4 polo-like kinase 4 -2.54782
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) -2.54493
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.54449
PTER phosphotriesterase related -2.54392
URM1 ubiquitin related modifier 1 -2.54176
CHURC1-FNTB CHURC1-FNTB readthrough -2.53891
NFE2L2 nuclear factor, erythroid 2-like 2 -2.5388
CLDN1 claudin 1 -2.53634
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.53601
MPDU1 mannose-P-dolichol utilization defect 1 -2.53422
SEPTIN8 septin 8 -2.53195
CASD1 CAS1 domain containing 1 -2.53149
SELL selectin L -2.53097
ELAC2 elaC ribonuclease Z 2 -2.52909
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -2.52634
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.52488
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.52458
OXCT1 3-oxoacid CoA transferase 1 -2.52187
CDK6 cyclin-dependent kinase 6 -2.51794
DOCK5 dedicator of cytokinesis 5 -2.51471
NID2 nidogen 2 (osteonidogen) -2.51257
MBNL1 muscleblind-like splicing regulator 1 -2.51094
SMYD5 SMYD family member 5 -2.51091
NOP14 NOP14 nucleolar protein -2.50862
RAD23B RAD23 homolog B (S. cerevisiae) -2.5069
NRIP1 nuclear receptor interacting protein 1 -2.50655
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -2.50466
CCL19 chemokine (C-C motif) ligand 19 -2.50055
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -2.49961
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase -2.4994
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -2.49803
VCAN versican -2.49326
NME1 NME/NM23 nucleoside diphosphate kinase 1 -2.49215
MZT2B mitotic spindle organizing protein 2B -2.48629
PEA15 phosphoprotein enriched in astrocytes 15 -2.483
APOH apolipoprotein H (beta-2-glycoprotein I) -2.48035
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) -2.4798
SAA4 serum amyloid A4, constitutive -2.47931
F9 coagulation factor IX -2.47849
S100A13 S100 calcium binding protein A13 -2.47398
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -2.47227
ERLIN1 ER lipid raft associated 1 -2.47192
CPNE3 copine III -2.47146
ADORA2B adenosine A2b receptor -2.47105
FHL2 four and a half LIM domains 2 -2.46596
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.45673
ARL14 ADP-ribosylation factor-like 14 -2.45333
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -2.45184
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -2.45124
NR1H4 nuclear receptor subfamily 1, group H, member 4 -2.45033
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -2.4494
RPH3AL rabphilin 3A-like (without C2 domains) -2.44751
PDCD5 programmed cell death 5 -2.4452
CD99 CD99 molecule -2.43958
SMYD2 SET and MYND domain containing 2 -2.43861
TF transferrin -2.43591
NCAPH non-SMC condensin I complex, subunit H -2.42928
VARS1 valyl-tRNA synthetase 1 -2.42742
ATP5MC1 ATP synthase membrane subunit c locus 1 -2.42369
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled -2.41522
PYCR1 pyrroline-5-carboxylate reductase 1 -2.41172
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -2.40383
PLCB4 phospholipase C, beta 4 -2.40371
IRAK1 interleukin-1 receptor-associated kinase 1 -2.39507
UFL1 UFM1-specific ligase 1 -2.39294
PARVB parvin, beta -2.37583
VRK2 vaccinia related kinase 2 -2.37466
AGMAT agmatine ureohydrolase (agmatinase) -2.37162
MPO myeloperoxidase -2.37053
SPIN2B spindlin family, member 2B -2.36925
GSTO1 glutathione S-transferase omega 1 -2.36659
SHCBP1 SHC SH2-domain binding protein 1 -2.35874
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.35661
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -2.34929
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -2.34916
CEP170 centrosomal protein 170kDa -2.34399
FBXW4 F-box and WD repeat domain containing 4 -2.34174
EXOC5 exocyst complex component 5 -2.33807
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.33343
RIMS1 regulating synaptic membrane exocytosis 1 -2.33291
RFX7 regulatory factor X, 7 -2.32375
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) -2.32279
C1QBP complement component 1, q subcomponent binding protein -2.32244
HMGB2 high mobility group box 2 -2.32005
ENTR1 endosome associated trafficking regulator 1 -2.31933
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -2.31931
RANGAP1 Ran GTPase activating protein 1 -2.31209
MED17 mediator complex subunit 17 -2.31018
MCM7 minichromosome maintenance complex component 7 -2.30476
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -2.30308
MAK16 MAK16 homolog (S. cerevisiae) -2.30295
LATS1 large tumor suppressor kinase 1 -2.29997
ANKRD34C ankyrin repeat domain 34C -2.29987
PDE10A phosphodiesterase 10A -2.29781
CHAF1B chromatin assembly factor 1, subunit B (p60) -2.29771
RRM2 ribonucleotide reductase M2 -2.29703
ASB9 ankyrin repeat and SOCS box containing 9 -2.29645
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.29266
PTPRM protein tyrosine phosphatase, receptor type, M -2.29012
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) -2.28425
CTPS2 CTP synthase 2 -2.27772
SEPTIN11 septin 11 -2.27481
FAM174C family with sequence similarity 174 member C -2.26961
ORM1 orosomucoid 1 -2.2686
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -2.26556
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.26524
GRID1 glutamate receptor, ionotropic, delta 1 -2.26406
ACOD1 aconitate decarboxylase 1 -2.26345
SEH1L SEH1-like (S. cerevisiae) -2.26335
TTF2 transcription termination factor, RNA polymerase II -2.26136
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -2.25963
DUOX2 dual oxidase 2 -2.24773
ALG9 ALG9, alpha-1,2-mannosyltransferase -2.24621
TFF2 trefoil factor 2 -2.24532
FANCG Fanconi anemia, complementation group G -2.24374
APOA1 apolipoprotein A-I -2.24279
CERS1 ceramide synthase 1 -2.2427
RAI14 retinoic acid induced 14 -2.23993
TYMS thymidylate synthetase -2.23875
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -2.2386
NLE1 notchless homolog 1 (Drosophila) -2.23818
SDAD1 SDA1 domain containing 1 -2.23513
APOC3 apolipoprotein C-III -2.23477
MRPL39 mitochondrial ribosomal protein L39 -2.23374
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -2.23317
CTSE cathepsin E -2.23146
CDCA3 cell division cycle associated 3 -2.22862
FERMT1 fermitin family member 1 -2.22815
PARPBP PARP1 binding protein -2.22773
CA5A carbonic anhydrase VA, mitochondrial -2.22505
RBBP4 retinoblastoma binding protein 4 -2.22316
APOE apolipoprotein E -2.22306
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 -2.22302
CCNJ cyclin J -2.22295
SLC25A46 solute carrier family 25, member 46 -2.22218
EPHA2 EPH receptor A2 -2.22147
ZIM2 zinc finger, imprinted 2 -2.21922
FBXO5 F-box protein 5 -2.21921
CCT7 chaperonin containing TCP1, subunit 7 (eta) -2.21719
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.21622
TSHR thyroid stimulating hormone receptor -2.21323
ANAPC1 anaphase promoting complex subunit 1 -2.21316
LYRM1 LYR motif containing 1 -2.21117
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -2.20834
TMEM123 transmembrane protein 123 -2.20278
FBF1 Fas (TNFRSF6) binding factor 1 -2.20214
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.20168
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.19821
RCN1 reticulocalbin 1, EF-hand calcium binding domain -2.19798
STEAP1 six transmembrane epithelial antigen of the prostate 1 -2.19734
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa -2.19681
TMED5 transmembrane emp24 protein transport domain containing 5 -2.19657
ZFY zinc finger protein, Y-linked -2.19495
SECISBP2 SECIS binding protein 2 -2.19289
MCM5 minichromosome maintenance complex component 5 -2.19191
SOAT1 sterol O-acyltransferase 1 -2.18472
TUBGCP5 tubulin, gamma complex associated protein 5 -2.18227
CDC27 cell division cycle 27 -2.1811
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -2.17971
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -2.17656
XPOT exportin, tRNA -2.17343
DUT deoxyuridine triphosphatase -2.17218
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -2.17174
CRYBG3 beta-gamma crystallin domain containing 3 -2.17037
TUBGCP3 tubulin, gamma complex associated protein 3 -2.17026
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.17011
LRP12 low density lipoprotein receptor-related protein 12 -2.16156
GNG4 guanine nucleotide binding protein (G protein), gamma 4 -2.16137
SNRPA small nuclear ribonucleoprotein polypeptide A -2.15682
CENPM centromere protein M -2.15532
DHFR dihydrofolate reductase -2.15514
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 -2.15485
RELN reelin -2.15229
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -2.15212
CFP complement factor properdin -2.15179
HDAC2 histone deacetylase 2 -2.15135
CD1D CD1d molecule -2.15026
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.14999
FBL fibrillarin -2.14707
NME2 NME/NM23 nucleoside diphosphate kinase 2 -2.14646
FABP1 fatty acid binding protein 1, liver -2.14529
CUL5 cullin 5 -2.1439
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 -2.14376
MRPL24 mitochondrial ribosomal protein L24 -2.14368
EXOSC10 exosome component 10 -2.14201
MAPK6 mitogen-activated protein kinase 6 -2.13836
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.13803
SNU13 small nuclear ribonucleoprotein 13 -2.13631
QDPR quinoid dihydropteridine reductase -2.13373
GCN1 GCN1 activator of EIF2AK4 -2.13337
POLR1G RNA polymerase I subunit G -2.13327
DCAF17 DDB1 and CUL4 associated factor 17 -2.1321
DPP3 dipeptidyl-peptidase 3 -2.12934
PUM3 pumilio RNA binding family member 3 -2.12923
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 -2.12662
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.12491
WDR18 WD repeat domain 18 -2.12273
MCRS1 microspherule protein 1 -2.12095
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -2.11838
LMF2 lipase maturation factor 2 -2.11759
ITPRID2 ITPR interacting domain containing 2 -2.11658
MRPS7 mitochondrial ribosomal protein S7 -2.11305
SUMO4 small ubiquitin-like modifier 4 -2.11272
RABEPK Rab9 effector protein with kelch motifs -2.11214
MTO1 mitochondrial tRNA translation optimization 1 -2.11132
GPN1 GPN-loop GTPase 1 -2.10634
WSB2 WD repeat and SOCS box containing 2 -2.10537
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa -2.10461
STOML2 stomatin (EPB72)-like 2 -2.10441
SLCO1B3 solute carrier organic anion transporter family, member 1B3 -2.10321
MYL1 myosin, light chain 1, alkali; skeletal, fast -2.09342
LOC100652777 group 10 secretory phospholipase A2-like -2.09117
PFAS phosphoribosylformylglycinamidine synthase -2.08894
CAPN15 calpain 15 -2.08887
LUZP2 leucine zipper protein 2 -2.08875
SF3A3 splicing factor 3a, subunit 3, 60kDa -2.08731
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain -2.08664
PVR poliovirus receptor -2.08049
GSTM3 glutathione S-transferase mu 3 (brain) -2.0799
RAB32 RAB32, member RAS oncogene family -2.07928
YAP1 Yes-associated protein 1 -2.07742
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -2.07697
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) -2.07541
FPR2 formyl peptide receptor 2 -2.07524
EML4 echinoderm microtubule associated protein like 4 -2.07515
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -2.07308
HPR haptoglobin-related protein -2.07197
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.07076
ADH6 alcohol dehydrogenase 6 (class V) -2.0706
EPS8L3 EPS8-like 3 -2.06846
MSRA methionine sulfoxide reductase A -2.06843
CCNH cyclin H -2.06806
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -2.06729
ZPR1 ZPR1 zinc finger -2.06625
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.06492
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.06186
PES1 pescadillo ribosomal biogenesis factor 1 -2.06178
NIT2 nitrilase family, member 2 -2.05993
E2F8 E2F transcription factor 8 -2.05639
HPD 4-hydroxyphenylpyruvate dioxygenase -2.05597
SNRPE small nuclear ribonucleoprotein polypeptide E -2.05485
TACC3 transforming, acidic coiled-coil containing protein 3 -2.05471
RNPEP arginyl aminopeptidase (aminopeptidase B) -2.05191
NLRX1 NLR family member X1 -2.05182
TRAF1 TNF receptor-associated factor 1 -2.05152
NGRN neugrin, neurite outgrowth associated -2.04845
THYN1 thymocyte nuclear protein 1 -2.04712
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.04674
ZNF324B zinc finger protein 324B -2.04345
ELL2 elongation factor, RNA polymerase II, 2 -2.04281
RWDD3 RWD domain containing 3 -2.0412
PON2 paraoxonase 2 -2.04088
SRPK1 SRSF protein kinase 1 -2.04016
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 -2.04014
PKN2 protein kinase N2 -2.03867
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.03702
RAB33B RAB33B, member RAS oncogene family -2.03564
SORD sorbitol dehydrogenase -2.03535
RBL1 retinoblastoma-like 1 -2.03487
NES nestin -2.03466
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) -2.03435
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -2.03246
CCND1 cyclin D1 -2.03034
KCTD3 potassium channel tetramerization domain containing 3 -2.02947
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -2.02892
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -2.02707
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -2.02679
GCFC2 GC-rich sequence DNA-binding factor 2 -2.02675
MMP8 matrix metallopeptidase 8 -2.02659
MATN3 matrilin 3 -2.02394
RAD51C RAD51 paralog C -2.02336
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -2.02192
FST follistatin -2.02176
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 -2.02152
LASP1 LIM and SH3 protein 1 -2.01981
PARK7 parkinson protein 7 -2.01956
SAP30 Sin3A-associated protein, 30kDa -2.01655
TPGS2 tubulin polyglutamylase complex subunit 2 -2.01487
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -2.01486
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -2.01341
CTPS1 CTP synthase 1 -2.0102
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.00884
ENO3 enolase 3 (beta, muscle) -2.00764
HMGB1 high mobility group box 1 -2.00731
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.00705
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.00653
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -2.00421
TMPO thymopoietin -2.00217
STS steroid sulfatase (microsomal), isozyme S -2.00137
ACYP2 acylphosphatase 2, muscle type -2.00074