CRCGN009_HEPG2_24H:K17 Gene Set
Genes
37 genes differentially expressed following the CRCGN009_HEPG2_24H:K17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
7.558
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
5.45316
|
|
MAP7
|
microtubule-associated protein 7
|
5.32137
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.07875
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.99625
|
|
LCN2
|
lipocalin 2
|
3.76068
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.50571
|
|
UBQLN2
|
ubiquilin 2
|
3.41805
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.27434
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.27411
|
|
MOK
|
MOK protein kinase
|
3.19138
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.50781
|
|
IDE
|
insulin-degrading enzyme
|
2.50358
|
|
CBR3
|
carbonyl reductase 3
|
2.37999
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
2.33281
|
|
FZD7
|
frizzled class receptor 7
|
2.22796
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.16935
|
|
CRTC3
|
CREB regulated transcription coactivator 3
|
2.04398
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.38021
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.763
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-5.33315
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.08276
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-3.87702
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.77527
|
|
EGF
|
epidermal growth factor
|
-3.67644
|
|
SCAND1
|
SCAN domain containing 1
|
-3.53733
|
|
TLR4
|
toll-like receptor 4
|
-2.99362
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.83914
|
|
LDHD
|
lactate dehydrogenase D
|
-2.83318
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.8307
|
|
RNF167
|
ring finger protein 167
|
-2.62583
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.61853
|
|
CCNB1
|
cyclin B1
|
-2.45986
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-2.35992
|
|
SERTAD3
|
SERTA domain containing 3
|
-2.27851
|
|
IRF2
|
interferon regulatory factor 2
|
-2.03678
|
|
MVP
|
major vault protein
|
-2.02972
|
