| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | (2-chloroethyl)trimethylammonium chloride 40.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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68 genes differentially expressed following the CRCGN009_HEPG2_24H:K19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL39L | ribosomal protein L39-like | 6.81556 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 5.808 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 5.1078 |
| MYLK | myosin light chain kinase | 5.05658 |
| GPATCH8 | G patch domain containing 8 | 4.8343 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.77661 |
| STK10 | serine/threonine kinase 10 | 4.59186 |
| ADRB2 | adrenoceptor beta 2, surface | 4.51342 |
| LCN2 | lipocalin 2 | 4.48792 |
| CYCS | cytochrome c, somatic | 4.37159 |
| FPGS | folylpolyglutamate synthase | 3.64119 |
| MAP7 | microtubule-associated protein 7 | 3.25423 |
| CHN1 | chimerin 1 | 3.18602 |
| ABHD6 | abhydrolase domain containing 6 | 3.06348 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 3.02142 |
| CCNF | cyclin F | 2.93055 |
| RPA3 | replication protein A3, 14kDa | 2.42948 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | 2.40286 |
| RPL27A | ribosomal protein L27a | 2.30704 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.29161 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.22841 |
| LOXL1 | lysyl oxidase-like 1 | 2.21683 |
| MAT2B | methionine adenosyltransferase II, beta | 2.17484 |
| S100B | S100 calcium binding protein B | 2.16351 |
| RPL7A | ribosomal protein L7a | 2.1584 |
| TBP | TATA box binding protein | 2.14208 |
| RPS10 | ribosomal protein S10 | 2.08709 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 2.06306 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 2.0294 |
| RNF38 | ring finger protein 38 | 2.00956 |
| CCNA1 | cyclin A1 | 2.00859 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.29821 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.18952 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.87025 |
| TRIB3 | tribbles pseudokinase 3 | -4.69449 |
| DNM1L | dynamin 1-like | -4.65033 |
| ADI1 | acireductone dioxygenase 1 | -4.58292 |
| PCNA | proliferating cell nuclear antigen | -4.42132 |
| ENOPH1 | enolase-phosphatase 1 | -4.34601 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.97024 |
| TLR4 | toll-like receptor 4 | -3.78336 |
| CCNB2 | cyclin B2 | -3.4942 |
| VDAC1 | voltage-dependent anion channel 1 | -3.44368 |
| STAMBP | STAM binding protein | -3.14969 |
| CCNB1 | cyclin B1 | -3.06896 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.87306 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 | -2.62832 |
| HYOU1 | hypoxia up-regulated 1 | -2.50587 |
| CD22 | CD22 molecule | -2.43677 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -2.34263 |
| FGF3 | fibroblast growth factor 3 | -2.29067 |
| OPN1MW3 | opsin 1, medium wave sensitive 3 | -2.26753 |
| INTS13 | integrator complex subunit 13 | -2.25809 |
| TAOK3 | TAO kinase 3 | -2.21642 |
| PLA2G15 | phospholipase A2, group XV | -2.17497 |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) | -2.14881 |
| TTYH1 | tweety family member 1 | -2.14153 |
| SPAG4 | sperm associated antigen 4 | -2.12645 |
| EMC10 | ER membrane protein complex subunit 10 | -2.10378 |
| CHD6 | chromodomain helicase DNA binding protein 6 | -2.10207 |
| DCAF13 | DDB1 and CUL4 associated factor 13 | -2.08907 |
| IL12RB1 | interleukin 12 receptor, beta 1 | -2.08289 |
| STXBP1 | syntaxin binding protein 1 | -2.06558 |
| NMUR1 | neuromedin U receptor 1 | -2.05463 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -2.03679 |
| GLOD4 | glyoxalase domain containing 4 | -2.0213 |
| CGREF1 | cell growth regulator with EF-hand domain 1 | -2.01606 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 | -2.01099 |
