| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | (2-chloroethyl)trimethylammonium chloride 10.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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56 genes differentially expressed following the CRCGN009_HEPG2_24H:K21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 6.49329 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 5.07778 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.53036 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 4.33936 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.12193 |
| JADE2 | jade family PHD finger 2 | 3.92476 |
| CHN1 | chimerin 1 | 3.88721 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.75623 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.27041 |
| EGF | epidermal growth factor | 3.18647 |
| CORO1A | coronin, actin binding protein, 1A | 2.88108 |
| VGLL4 | vestigial-like family member 4 | 2.76959 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.72001 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.65583 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.62063 |
| CYCS | cytochrome c, somatic | 2.56364 |
| UROS | uroporphyrinogen III synthase | 2.54066 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 2.45877 |
| DIPK1A | divergent protein kinase domain 1A | 2.40151 |
| RBBP5 | retinoblastoma binding protein 5 | 2.27567 |
| MYLK | myosin light chain kinase | 2.22168 |
| CBR3 | carbonyl reductase 3 | 2.22125 |
| HDAC3 | histone deacetylase 3 | 2.21262 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.1812 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.12971 |
| TEX10 | testis expressed 10 | 2.10976 |
| PTK2 | protein tyrosine kinase 2 | 2.09445 |
| KIF20A | kinesin family member 20A | 2.03989 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 2.01778 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TLR4 | toll-like receptor 4 | -5.70554 |
| GNAS | GNAS complex locus | -5.39603 |
| TRIB3 | tribbles pseudokinase 3 | -5.25278 |
| LDHD | lactate dehydrogenase D | -5.15967 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -5.13555 |
| DUSP6 | dual specificity phosphatase 6 | -4.99852 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -4.95631 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.82225 |
| DNM1L | dynamin 1-like | -4.80787 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.73294 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.77562 |
| RNF167 | ring finger protein 167 | -3.25944 |
| HYOU1 | hypoxia up-regulated 1 | -2.92602 |
| LAP3 | leucine aminopeptidase 3 | -2.8496 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.84703 |
| RBM15B | RNA binding motif protein 15B | -2.71815 |
| TLCD3A | TLC domain containing 3A | -2.59852 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.59815 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.58702 |
| SNX11 | sorting nexin 11 | -2.48761 |
| FHL2 | four and a half LIM domains 2 | -2.4571 |
| GOLT1B | golgi transport 1B | -2.34565 |
| CD320 | CD320 molecule | -2.22349 |
| SLC35F2 | solute carrier family 35, member F2 | -2.16991 |
| SOAT2 | sterol O-acyltransferase 2 | -2.10874 |
| PCNA | proliferating cell nuclear antigen | -2.0486 |
| HOXA11 | homeobox A11 | -2.00774 |
