CRCGN009_HEPG2_24H:K22 Gene Set
Genes
60 genes differentially expressed following the CRCGN009_HEPG2_24H:K22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAMLD1
|
mastermind-like domain containing 1
|
8.10102
|
|
CYCS
|
cytochrome c, somatic
|
6.22581
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.94298
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
5.22754
|
|
STIMATE
|
STIM activating enhancer
|
4.37013
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.56995
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
3.20463
|
|
MCOLN1
|
mucolipin 1
|
3.20197
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.10135
|
|
PRR15L
|
proline rich 15-like
|
3.02276
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.89996
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.82817
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.78477
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
2.65381
|
|
NUCB2
|
nucleobindin 2
|
2.52697
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.49029
|
|
VGLL4
|
vestigial-like family member 4
|
2.45399
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.44764
|
|
CHN1
|
chimerin 1
|
2.41318
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
2.41255
|
|
PSMD3
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
|
2.37953
|
|
KIF20A
|
kinesin family member 20A
|
2.33722
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.25669
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
2.24387
|
|
AXIN1
|
axin 1
|
2.21624
|
|
FKBPL
|
FK506 binding protein like
|
2.19289
|
|
EGF
|
epidermal growth factor
|
2.16133
|
|
ARL4A
|
ADP-ribosylation factor-like 4A
|
2.16038
|
|
TMA16
|
translation machinery associated 16 homolog (S. cerevisiae)
|
2.10289
|
|
CTSL
|
cathepsin L
|
2.03766
|
|
WDR13
|
WD repeat domain 13
|
2.03169
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.00175
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-7.13367
|
|
GNAS
|
GNAS complex locus
|
-6.25663
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.26976
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.6427
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-4.58309
|
|
CCNB2
|
cyclin B2
|
-3.98291
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-3.87945
|
|
CDC20
|
cell division cycle 20
|
-3.87575
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.69974
|
|
CSK
|
c-src tyrosine kinase
|
-3.6681
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.47005
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.32018
|
|
COG2
|
component of oligomeric golgi complex 2
|
-3.20682
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.19781
|
|
CAB39
|
calcium binding protein 39
|
-3.16095
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.10992
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.99254
|
|
TLR4
|
toll-like receptor 4
|
-2.87301
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.52578
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.51355
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.23967
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.1537
|
|
GAA
|
glucosidase, alpha; acid
|
-2.12919
|
|
LDHD
|
lactate dehydrogenase D
|
-2.09915
|
|
RPN1
|
ribophorin I
|
-2.06829
|
|
F5
|
coagulation factor V (proaccelerin, labile factor)
|
-2.03221
|
|
PDZD2
|
PDZ domain containing 2
|
-2.00395
|
|
NBEAL2
|
neurobeachin-like 2
|
-2.00271
|
