CRCGN009_HEPG2_24H:K23 Gene Set
Genes
53 genes differentially expressed following the CRCGN009_HEPG2_24H:K23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
7.35599
|
|
LCN2
|
lipocalin 2
|
5.65834
|
|
PRKCH
|
protein kinase C, eta
|
5.65078
|
|
PMM2
|
phosphomannomutase 2
|
4.17635
|
|
NOTCH1
|
notch 1
|
4.16894
|
|
MEST
|
mesoderm specific transcript
|
4.13938
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.94261
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.63273
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.46022
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.44473
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.33559
|
|
ZNF589
|
zinc finger protein 589
|
3.21934
|
|
AXIN1
|
axin 1
|
3.07352
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.02327
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.01702
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.74529
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.40019
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.3797
|
|
CCNA1
|
cyclin A1
|
2.35035
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.23252
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.16879
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.12132
|
|
TBC1D31
|
TBC1 domain family, member 31
|
2.03824
|
|
RBX1
|
ring-box 1, E3 ubiquitin protein ligase
|
2.03297
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.02377
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.02023
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.00603
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC25B
|
cell division cycle 25B
|
-4.45525
|
|
CDC20
|
cell division cycle 20
|
-4.23158
|
|
ZNF586
|
zinc finger protein 586
|
-3.90503
|
|
LDHD
|
lactate dehydrogenase D
|
-3.84829
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.8398
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.70449
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.6512
|
|
CSK
|
c-src tyrosine kinase
|
-3.63202
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.55153
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.45852
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.42949
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.30736
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.08522
|
|
SCCPDH
|
saccharopine dehydrogenase (putative)
|
-3.01032
|
|
EGF
|
epidermal growth factor
|
-2.76657
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.70046
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.5074
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
-2.39251
|
|
CCNB2
|
cyclin B2
|
-2.34903
|
|
PROS1
|
protein S (alpha)
|
-2.25721
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.16093
|
|
SNX11
|
sorting nexin 11
|
-2.1322
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.11953
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.10047
|
|
PPY
|
pancreatic polypeptide
|
-2.09816
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.08287
|
