CRCGN009_HEPG2_24H:L01 Gene Set
Genes
46 genes differentially expressed following the CRCGN009_HEPG2_24H:L01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
4.20714
|
|
UBQLN2
|
ubiquilin 2
|
3.77936
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.68123
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
3.65553
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.41967
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.30288
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.9987
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.88899
|
|
CHN1
|
chimerin 1
|
2.87005
|
|
LCN2
|
lipocalin 2
|
2.85143
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
2.83287
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.76459
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.76447
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.65676
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
2.62065
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.53252
|
|
SATB1
|
SATB homeobox 1
|
2.48694
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.25213
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.24086
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.08746
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-6.22628
|
|
TLR4
|
toll-like receptor 4
|
-6.02857
|
|
CDC25B
|
cell division cycle 25B
|
-4.7312
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-4.1913
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.98682
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.93667
|
|
CD320
|
CD320 molecule
|
-3.58071
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.50527
|
|
CD58
|
CD58 molecule
|
-3.35252
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.9913
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.83806
|
|
GNAS
|
GNAS complex locus
|
-2.61261
|
|
CPNE3
|
copine III
|
-2.52266
|
|
CCNH
|
cyclin H
|
-2.51563
|
|
TPH1
|
tryptophan hydroxylase 1
|
-2.34962
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.31187
|
|
XPO7
|
exportin 7
|
-2.28191
|
|
MANEA
|
mannosidase, endo-alpha
|
-2.25907
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
-2.22207
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.18321
|
|
ARID4B
|
AT rich interactive domain 4B (RBP1-like)
|
-2.15426
|
|
ANKRD36C
|
ankyrin repeat domain 36C
|
-2.15277
|
|
STXBP3
|
syntaxin binding protein 3
|
-2.13081
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.04656
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.04504
|
|
FGL2
|
fibrinogen-like 2
|
-2.00011
|
