| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | aspirin 19.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
60 genes differentially expressed following the CRCGN009_HEPG2_24H:L02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 5.60735 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.47179 |
| STIMATE | STIM activating enhancer | 5.35342 |
| NOTCH1 | notch 1 | 5.03465 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.98717 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.09284 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.83111 |
| PLS1 | plastin 1 | 3.81691 |
| PRKCH | protein kinase C, eta | 3.30311 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.2077 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.8446 |
| KIFBP | kinesin family binding protein | 2.74992 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.66242 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 2.45585 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.44391 |
| EPN2 | epsin 2 | 2.40771 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 2.39273 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.35953 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 2.30634 |
| PMM2 | phosphomannomutase 2 | 2.24657 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.14929 |
| EDN1 | endothelin 1 | 2.13653 |
| COPS7A | COP9 signalosome subunit 7A | 2.09972 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 | 2.09814 |
| CDC23 | cell division cycle 23 | 2.0726 |
| TAC4 | tachykinin 4 (hemokinin) | 2.07255 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 2.02812 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -8.77306 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.03623 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.012 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -5.55032 |
| CSK | c-src tyrosine kinase | -5.53921 |
| CDC20 | cell division cycle 20 | -4.13933 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.01914 |
| CCDC86 | coiled-coil domain containing 86 | -3.99588 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.99038 |
| LAP3 | leucine aminopeptidase 3 | -3.82033 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.56098 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.53963 |
| SLC35F2 | solute carrier family 35, member F2 | -3.40524 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.39557 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.21016 |
| VDAC1 | voltage-dependent anion channel 1 | -3.20917 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.01269 |
| CCNB2 | cyclin B2 | -2.99631 |
| RNF167 | ring finger protein 167 | -2.97174 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.6476 |
| TCTN1 | tectonic family member 1 | -2.51989 |
| ICAM3 | intercellular adhesion molecule 3 | -2.26009 |
| HSPA8 | heat shock 70kDa protein 8 | -2.25732 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.25317 |
| HEATR1 | HEAT repeat containing 1 | -2.24821 |
| YME1L1 | YME1-like 1 ATPase | -2.16154 |
| HYOU1 | hypoxia up-regulated 1 | -2.07117 |
| BTNL8 | butyrophilin-like 8 | -2.06623 |
| LMBRD1 | LMBR1 domain containing 1 | -2.06209 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) | -2.05864 |
| ZNF134 | zinc finger protein 134 | -2.02797 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.02795 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -2.02763 |
