CRCGN009_HEPG2_24H:L05 Gene Set
Genes
43 genes differentially expressed following the CRCGN009_HEPG2_24H:L05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
7.21472
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
5.08938
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.88542
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.3814
|
|
STK10
|
serine/threonine kinase 10
|
4.22885
|
|
PMM2
|
phosphomannomutase 2
|
4.17839
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.15366
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.02418
|
|
HOXA10
|
homeobox A10
|
3.97828
|
|
CBR3
|
carbonyl reductase 3
|
3.91529
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.78645
|
|
STXBP2
|
syntaxin binding protein 2
|
3.42123
|
|
EVL
|
Enah/Vasp-like
|
3.09546
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.01594
|
|
RRAGA
|
Ras-related GTP binding A
|
2.83649
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.72605
|
|
TENT4A
|
terminal nucleotidyltransferase 4A
|
2.62036
|
|
LCN2
|
lipocalin 2
|
2.60723
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.28628
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.22563
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.20863
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.14269
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-5.26766
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.58616
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.08435
|
|
EGF
|
epidermal growth factor
|
-4.07743
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.0713
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.81112
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.79884
|
|
PEG10
|
paternally expressed 10
|
-3.49002
|
|
SNX11
|
sorting nexin 11
|
-3.4773
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.46338
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.84861
|
|
MTA1
|
metastasis associated 1
|
-2.78008
|
|
GDF15
|
growth differentiation factor 15
|
-2.54966
|
|
SCCPDH
|
saccharopine dehydrogenase (putative)
|
-2.48947
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
-2.24962
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
-2.22938
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.19295
|
|
WASHC4
|
WASH complex subunit 4
|
-2.12765
|
|
ZW10
|
zw10 kinetochore protein
|
-2.10187
|
|
TOPBP1
|
topoisomerase (DNA) II binding protein 1
|
-2.0525
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.04618
|
