| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | aspirin 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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104 genes differentially expressed following the CRCGN009_HEPG2_24H:L06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNF | cyclin F | 5.2297 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.06651 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.93893 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.55374 |
| ADRB2 | adrenoceptor beta 2, surface | 4.51023 |
| ABHD4 | abhydrolase domain containing 4 | 4.30175 |
| MEST | mesoderm specific transcript | 4.24786 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.24211 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.21443 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.93169 |
| SQOR | sulfide quinone oxidoreductase | 3.82548 |
| ABHD6 | abhydrolase domain containing 6 | 3.72077 |
| FZD7 | frizzled class receptor 7 | 3.698 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.61711 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.60827 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.58262 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.47382 |
| HDGFL3 | HDGF like 3 | 3.44526 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 3.42941 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 3.36299 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.32445 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 3.11908 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.10223 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.05176 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.88454 |
| HEBP1 | heme binding protein 1 | 2.66116 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like | 2.59631 |
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon | 2.48167 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.40397 |
| SRGN | serglycin | 2.34412 |
| A4GALT | alpha 1,4-galactosyltransferase | 2.25941 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | 2.23346 |
| SKA1 | spindle and kinetochore associated complex subunit 1 | 2.22705 |
| SFTPB | surfactant protein B | 2.22223 |
| OSGEP | O-sialoglycoprotein endopeptidase | 2.19422 |
| INTS6 | integrator complex subunit 6 | 2.17035 |
| TESK1 | testis-specific kinase 1 | 2.16688 |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa | 2.16595 |
| KIF18A | kinesin family member 18A | 2.14843 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 | 2.13401 |
| PITX2 | paired-like homeodomain 2 | 2.13061 |
| ANXA8L1 | annexin A8-like 1 | 2.12429 |
| PGP | phosphoglycolate phosphatase | 2.08709 |
| MORN1 | MORN repeat containing 1 | 2.07078 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) | 2.0686 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 2.06722 |
| NKG7 | natural killer cell granule protein 7 | 2.06493 |
| RAB40C | RAB40C, member RAS oncogene family | 2.06231 |
| COPS7A | COP9 signalosome subunit 7A | 2.02542 |
| CPOX | coproporphyrinogen oxidase | 2.01862 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 2.00727 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -8.60918 |
| TLR4 | toll-like receptor 4 | -8.44497 |
| CDC20 | cell division cycle 20 | -6.57106 |
| GNAS | GNAS complex locus | -6.49405 |
| ZNF586 | zinc finger protein 586 | -6.05093 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.88307 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.54643 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.53086 |
| VAT1 | vesicle amine transport 1 | -4.27593 |
| TRIB3 | tribbles pseudokinase 3 | -4.26231 |
| LDHD | lactate dehydrogenase D | -4.25431 |
| CCNB2 | cyclin B2 | -4.12314 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -3.85966 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.79149 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -3.55407 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.44703 |
| SNX11 | sorting nexin 11 | -3.40624 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.38803 |
| HEATR1 | HEAT repeat containing 1 | -3.0864 |
| IFRD2 | interferon-related developmental regulator 2 | -3.08403 |
| RGS2 | regulator of G-protein signaling 2 | -2.96866 |
| PRPF4 | pre-mRNA processing factor 4 | -2.93487 |
| PRSS58 | protease, serine, 58 | -2.78218 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.71372 |
| ILK | integrin-linked kinase | -2.6053 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.52271 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -2.5106 |
| H3-3A | H3.3 histone A | -2.4279 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -2.40726 |
| ZNF223 | zinc finger protein 223 | -2.36404 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -2.32543 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -2.297 |
| CLTC | clathrin, heavy chain (Hc) | -2.29167 |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) | -2.27687 |
| SV2C | synaptic vesicle glycoprotein 2C | -2.24894 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -2.19321 |
| CUZD1 | CUB and zona pellucida-like domains 1 | -2.17222 |
| GDF3 | growth differentiation factor 3 | -2.14844 |
| LIN28A | lin-28 homolog A (C. elegans) | -2.14323 |
| ZNF419 | zinc finger protein 419 | -2.11972 |
| CD40LG | CD40 ligand | -2.10351 |
| ZNF134 | zinc finger protein 134 | -2.08911 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -2.08239 |
| CD1B | CD1b molecule | -2.08009 |
| FAM114A2 | family with sequence similarity 114, member A2 | -2.07712 |
| PRDM14 | PR domain containing 14 | -2.06326 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | -2.05116 |
| PRAMEF26 | PRAME family member 26 | -2.04431 |
| CCL11 | chemokine (C-C motif) ligand 11 | -2.03365 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | -2.02735 |
| MS4A5 | membrane-spanning 4-domains, subfamily A, member 5 | -2.019 |
| CDH20 | cadherin 20, type 2 | -2.01694 |
| ZIC3 | Zic family member 3 | -2.00162 |
