CRCGN009_HEPG2_24H:L09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4,4'-thiobis(6-tert-butyl-m-cresol) 10.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1063 genes differentially expressed following the CRCGN009_HEPG2_24H:L09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LCN2 lipocalin 2 10.0
CDPF1 cysteine-rich, DPF motif domain containing 1 9.58786
STX1A syntaxin 1A (brain) 9.54302
TXNRD1 thioredoxin reductase 1 9.39654
TRIB3 tribbles pseudokinase 3 8.96603
CTSL cathepsin L 8.84116
MYC v-myc avian myelocytomatosis viral oncogene homolog 8.32066
TIMP2 TIMP metallopeptidase inhibitor 2 8.26163
FOSL1 FOS-like antigen 1 8.16608
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 7.86179
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 7.82569
GFOD1 glucose-fructose oxidoreductase domain containing 1 7.71904
IGFBP3 insulin-like growth factor binding protein 3 7.64895
ANO1 anoctamin 1, calcium activated chloride channel 7.63447
KIFBP kinesin family binding protein 7.51829
FHL2 four and a half LIM domains 2 7.4892
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 7.23998
CYCS cytochrome c, somatic 7.12758
INPP1 inositol polyphosphate-1-phosphatase 6.99933
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 6.95276
CASC3 cancer susceptibility candidate 3 6.81628
BIRC2 baculoviral IAP repeat containing 2 6.44316
TRIM13 tripartite motif containing 13 6.02793
GFPT1 glutamine--fructose-6-phosphate transaminase 1 5.98668
MICALL1 MICAL-like 1 5.87999
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 5.87062
IER3 immediate early response 3 5.86976
NR1H2 nuclear receptor subfamily 1, group H, member 2 5.85926
CDK7 cyclin-dependent kinase 7 5.85019
PNKP polynucleotide kinase 3'-phosphatase 5.76825
SQSTM1 sequestosome 1 5.70952
EGR1 early growth response 1 5.5818
CNPY3 canopy FGF signaling regulator 3 5.54019
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 5.44697
DNM1L dynamin 1-like 5.27369
TNIP1 TNFAIP3 interacting protein 1 5.26815
NUP58 nucleoporin 58 5.2678
TERF2IP telomeric repeat binding factor 2, interacting protein 5.26465
SQOR sulfide quinone oxidoreductase 5.26447
AARS1 alanyl-tRNA synthetase 1 5.22051
NOTCH1 notch 1 5.17252
MVP major vault protein 5.1637
ADO 2-aminoethanethiol (cysteamine) dioxygenase 5.13497
PTPN12 protein tyrosine phosphatase, non-receptor type 12 5.12989
TP53BP2 tumor protein p53 binding protein 2 5.1225
PRKCQ protein kinase C, theta 5.11619
DDIT4 DNA-damage-inducible transcript 4 5.11593
RAB11FIP2 RAB11 family interacting protein 2 (class I) 5.11209
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.02831
PPARG peroxisome proliferator-activated receptor gamma 5.00221
IL4R interleukin 4 receptor 4.95083
GOLT1B golgi transport 1B 4.94706
NPC1 Niemann-Pick disease, type C1 4.91004
FOXJ3 forkhead box J3 4.84906
TRIB1 tribbles pseudokinase 1 4.82267
CSNK1E casein kinase 1, epsilon 4.80488
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 4.75053
LSR lipolysis stimulated lipoprotein receptor 4.6493
ADGRE5 adhesion G protein-coupled receptor E5 4.61322
CGRRF1 cell growth regulator with ring finger domain 1 4.55679
KLHL21 kelch-like family member 21 4.55109
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 4.49544
CCNA1 cyclin A1 4.4515
JOSD1 Josephin domain containing 1 4.36211
BZW2 basic leucine zipper and W2 domains 2 4.34317
HLA-DMA major histocompatibility complex, class II, DM alpha 4.3243
SARS1 seryl-tRNA synthetase 1 4.30512
LOC128125814 uncharacterized LOC128125814 4.26759
FCHO1 FCH domain only 1 4.24575
JUN jun proto-oncogene 4.22285
TBPL1 TBP-like 1 4.221
LPAR2 lysophosphatidic acid receptor 2 4.20659
TICAM1 toll-like receptor adaptor molecule 1 4.19789
SMAD3 SMAD family member 3 4.1761
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 4.09952
LRP10 low density lipoprotein receptor-related protein 10 4.05785
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 4.0325
KDM5A lysine (K)-specific demethylase 5A 4.0008
SOX4 SRY (sex determining region Y)-box 4 3.99392
RHOG ras homolog family member G 3.97477
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 3.94559
IFRD1 interferon-related developmental regulator 1 3.91919
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 3.91494
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.89105
IKZF1 IKAROS family zinc finger 1 (Ikaros) 3.87091
DUSP8 dual specificity phosphatase 8 3.86163
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 3.79446
RAB11FIP1 RAB11 family interacting protein 1 (class I) 3.78502
CAMTA2 calmodulin binding transcription activator 2 3.76927
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 3.7622
STAT5B signal transducer and activator of transcription 5B 3.73334
PLK3 polo-like kinase 3 3.72634
ANKRD11 ankyrin repeat domain 11 3.7029
TBC1D15 TBC1 domain family, member 15 3.68835
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 3.68276
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 3.66615
NCK1 NCK adaptor protein 1 3.65219
SMNDC1 survival motor neuron domain containing 1 3.65031
LARP6 La ribonucleoprotein domain family, member 6 3.63354
BACE2 beta-site APP-cleaving enzyme 2 3.6312
ZFP36 ZFP36 ring finger protein 3.60711
GIPC1 GIPC PDZ domain containing family, member 1 3.60044
H2BC21 H2B clustered histone 21 3.59524
PCDHB11 protocadherin beta 11 3.56373
PRKCD protein kinase C, delta 3.55911
YARS1 tyrosyl-tRNA synthetase 1 3.55198
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.52461
ALAS1 5'-aminolevulinate synthase 1 3.5205
PRAF2 PRA1 domain family, member 2 3.51294
GRB10 growth factor receptor-bound protein 10 3.51206
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 3.51038
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 3.50522
CLK3 CDC-like kinase 3 3.50363
IER2 immediate early response 2 3.50221
EGFR epidermal growth factor receptor 3.477
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 3.46725
RBM6 RNA binding motif protein 6 3.45795
ATF4 activating transcription factor 4 3.45309
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 3.44762
CHD1 chromodomain helicase DNA binding protein 1 3.44275
TESK1 testis-specific kinase 1 3.43039
FPGS folylpolyglutamate synthase 3.42575
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 3.41646
CLIP4 CAP-GLY domain containing linker protein family, member 4 3.41472
PHKG2 phosphorylase kinase, gamma 2 (testis) 3.4047
EIF3D eukaryotic translation initiation factor 3, subunit D 3.39197
TOMM34 translocase of outer mitochondrial membrane 34 3.39026
YME1L1 YME1-like 1 ATPase 3.37528
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.36578
MBNL2 muscleblind-like splicing regulator 2 3.35683
SOCS2 suppressor of cytokine signaling 2 3.3425
PDZD8 PDZ domain containing 8 3.31086
CYTH2 cytohesin 2 3.30478
ACOT9 acyl-CoA thioesterase 9 3.29375
RALB v-ral simian leukemia viral oncogene homolog B 3.29143
ATP11B ATPase, class VI, type 11B 3.29057
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 3.27286
TRAPPC6A trafficking protein particle complex 6A 3.24906
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 3.2213
ZNF358 zinc finger protein 358 3.20398
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.20323
CAB39 calcium binding protein 39 3.20152
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 3.1965
SPAG7 sperm associated antigen 7 3.19002
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 3.18364
ZFAND1 zinc finger, AN1-type domain 1 3.1733
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 3.1705
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 3.16323
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.14988
GADD45B growth arrest and DNA-damage-inducible, beta 3.1488
MSRA methionine sulfoxide reductase A 3.14147
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 3.13483
PDE8A phosphodiesterase 8A 3.11667
CEP170B centrosomal protein 170B 3.1161
SPINT1 serine peptidase inhibitor, Kunitz type 1 3.10242
ZBTB10 zinc finger and BTB domain containing 10 3.0928
ADAP2 ArfGAP with dual PH domains 2 3.08338
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.07088
MEST mesoderm specific transcript 3.06793
BYSL bystin-like 3.06492
KDM6B lysine (K)-specific demethylase 6B 3.04621
RAI14 retinoic acid induced 14 3.04537
ZYX zyxin 3.04348
BIRC3 baculoviral IAP repeat containing 3 3.03288
RB1CC1 RB1-inducible coiled-coil 1 3.02031
PXDC1 PX domain containing 1 3.01739
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 3.00728
SFMBT1 Scm-like with four mbt domains 1 3.00135
GARS1 glycyl-tRNA synthetase 1 2.99249
WDR13 WD repeat domain 13 2.98905
ARID4B AT rich interactive domain 4B (RBP1-like) 2.9708
CORO1A coronin, actin binding protein, 1A 2.96951
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 2.96659
ADGRG1 adhesion G protein-coupled receptor G1 2.96273
NIBAN1 niban apoptosis regulator 1 2.96111
CLIP2 CAP-GLY domain containing linker protein 2 2.95868
CFLAR CASP8 and FADD-like apoptosis regulator 2.95455
TENT4A terminal nucleotidyltransferase 4A 2.95324
MYH9 myosin, heavy chain 9, non-muscle 2.95218
GTPBP2 GTP binding protein 2 2.95036
MBTD1 mbt domain containing 1 2.94363
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 2.93662
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.92907
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.92733
NRBF2 nuclear receptor binding factor 2 2.92659
GPC1 glypican 1 2.92559
CARMIL1 capping protein regulator and myosin 1 linker 1 2.92131
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.91812
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.91035
RYBP RING1 and YY1 binding protein 2.89982
PIH1D1 PIH1 domain containing 1 2.89492
MAP7 microtubule-associated protein 7 2.89491
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.89403
RLF rearranged L-myc fusion 2.88424
NDEL1 nudE neurodevelopment protein 1-like 1 2.88418
BTG3 BTG family, member 3 2.88185
GADD45A growth arrest and DNA-damage-inducible, alpha 2.87962
LIN37 lin-37 DREAM MuvB core complex component 2.86781
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.8633
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.85519
MTFR1 mitochondrial fission regulator 1 2.84967
MTCH1 mitochondrial carrier 1 2.84381
TBP TATA box binding protein 2.84144
NR1D2 nuclear receptor subfamily 1, group D, member 2 2.83976
ZNF410 zinc finger protein 410 2.81913
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.8154
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 2.8107
USP3 ubiquitin specific peptidase 3 2.80828
CARS1 cysteinyl-tRNA synthetase 1 2.79775
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.79741
ANKRD12 ankyrin repeat domain 12 2.79484
IL7R interleukin 7 receptor 2.7931
GOLT1A golgi transport 1A 2.78531
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.7823
CRISP2 cysteine-rich secretory protein 2 2.7799
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.77564
H2BC6 H2B clustered histone 6 2.77363
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 2.76805
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 2.75753
PTX3 pentraxin 3, long 2.75707
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.75223
PPARD peroxisome proliferator-activated receptor delta 2.75217
KLHL24 kelch-like family member 24 2.74869
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.74277
ZC3H15 zinc finger CCCH-type containing 15 2.74095
ZNF26 zinc finger protein 26 2.74025
MAPK13 mitogen-activated protein kinase 13 2.73937
ELF4 E74-like factor 4 (ets domain transcription factor) 2.73916
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.73832
PTPRK protein tyrosine phosphatase, receptor type, K 2.73306
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.72984
UPP1 uridine phosphorylase 1 2.71497
MYNN myoneurin 2.70597
KRT86 keratin 86, type II 2.69798
CSNK1G3 casein kinase 1, gamma 3 2.69542
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.68591
GHITM growth hormone inducible transmembrane protein 2.68064
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.67941
EVL Enah/Vasp-like 2.66455
KCMF1 potassium channel modulatory factor 1 2.66414
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 2.6596
EZR ezrin 2.64373
ODR4 odr-4 GPCR localization factor homolog 2.64326
MBNL1 muscleblind-like splicing regulator 1 2.62999
YY1AP1 YY1 associated protein 1 2.6238
BAMBI BMP and activin membrane-bound inhibitor 2.62061
WDR46 WD repeat domain 46 2.61585
ATF6 activating transcription factor 6 2.60361
MAP1S microtubule-associated protein 1S 2.60343
PTPN14 protein tyrosine phosphatase, non-receptor type 14 2.60153
SLC35F2 solute carrier family 35, member F2 2.59474
RSF1 remodeling and spacing factor 1 2.59136
IMP4 IMP4, U3 small nucleolar ribonucleoprotein 2.5913
KITLG KIT ligand 2.59068
RIOK3 RIO kinase 3 2.58839
VAT1 vesicle amine transport 1 2.58752
BAG6 BCL2-associated athanogene 6 2.58137
SH3GLB1 SH3-domain GRB2-like endophilin B1 2.5787
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.57671
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 2.57614
CLEC5A C-type lectin domain family 5, member A 2.57552
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 2.56776
ANGPTL2 angiopoietin-like 2 2.56675
IL18RAP interleukin 18 receptor accessory protein 2.56495
FSCN1 fascin actin-bundling protein 1 2.56245
SMIM40 small integral membrane protein 40 2.56063
HSPA13 heat shock protein 70kDa family, member 13 2.55343
EIF1B eukaryotic translation initiation factor 1B 2.54727
RGCC regulator of cell cycle 2.54556
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.54451
ATF3 activating transcription factor 3 2.54364
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.54078
REL v-rel avian reticuloendotheliosis viral oncogene homolog 2.53977
BCL10 B-cell CLL/lymphoma 10 2.5378
STAT5A signal transducer and activator of transcription 5A 2.52673
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.52599
FJX1 four jointed box 1 (Drosophila) 2.51401
IL1B interleukin 1, beta 2.51081
SRPK1 SRSF protein kinase 1 2.50903
ELOVL4 ELOVL fatty acid elongase 4 2.50664
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.50564
KLF7 Kruppel-like factor 7 (ubiquitous) 2.50216
EIF3A eukaryotic translation initiation factor 3, subunit A 2.50075
AKAP12 A kinase (PRKA) anchor protein 12 2.48953
KLF13 Kruppel-like factor 13 2.48915
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.48812
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.48782
ZC3H7A zinc finger CCCH-type containing 7A 2.48222
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 2.4705
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.46246
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 2.46077
N4BP3 NEDD4 binding protein 3 2.45903
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like 2.45731
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.45681
UVRAG UV radiation resistance associated 2.45602
KLF6 Kruppel-like factor 6 2.44737
EPPK1 epiplakin 1 2.44533
ARID5B AT rich interactive domain 5B (MRF1-like) 2.44441
PLPP6 phospholipid phosphatase 6 2.44096
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.43677
RFC2 replication factor C (activator 1) 2, 40kDa 2.43633
LOC127933115 uncharacterized LOC127933115 2.43441
WDR47 WD repeat domain 47 2.43279
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.42975
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 2.4296
CDK17 cyclin-dependent kinase 17 2.4293
TRAPPC10 trafficking protein particle complex 10 2.42397
LORICRIN loricrin cornified envelope precursor protein 2.42272
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 2.42253
SUN2 Sad1 and UNC84 domain containing 2 2.42094
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.41892
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 2.41796
CLTB clathrin, light chain B 2.41778
AP3M2 adaptor-related protein complex 3, mu 2 subunit 2.4168
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.41544
EPN2 epsin 2 2.41456
NFE2L2 nuclear factor, erythroid 2-like 2 2.40892
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 2.40344
GSTZ1 glutathione S-transferase zeta 1 2.40241
RGS10 regulator of G-protein signaling 10 2.39939
ELMO3 engulfment and cell motility 3 2.39747
BPI bactericidal/permeability-increasing protein 2.39512
LIF leukemia inhibitory factor 2.38079
TES testin LIM domain protein 2.37862
STRN4 striatin, calmodulin binding protein 4 2.37859
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 2.37717
SINHCAF SIN3-HDAC complex associated factor 2.37593
CCNJ cyclin J 2.3722
EIF4A2 eukaryotic translation initiation factor 4A2 2.36964
MNT MAX network transcriptional repressor 2.36851
PTBP2 polypyrimidine tract binding protein 2 2.36719
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 2.3637
IRF1 interferon regulatory factor 1 2.35874
FNBP4 formin binding protein 4 2.35819
CRYZL1 crystallin, zeta (quinone reductase)-like 1 2.35745
SNAI2 snail family zinc finger 2 2.3569
CCDC68 coiled-coil domain containing 68 2.35526
PARP6 poly (ADP-ribose) polymerase family, member 6 2.35456
SUCO SUN domain containing ossification factor 2.35412
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.35345
UNC5B unc-5 homolog B (C. elegans) 2.34955
SERINC1 serine incorporator 1 2.34386
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 2.34203
RIPK4 receptor-interacting serine-threonine kinase 4 2.33992
YJU2B YJU2 splicing factor homolog B 2.33744
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa 2.3372
PRR15L proline rich 15-like 2.33589
QTMAN queuosine-tRNA mannosyltransferase 2.33506
KDM3A lysine (K)-specific demethylase 3A 2.33251
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.33064
MTMR2 myotubularin related protein 2 2.32423
CCNL1 cyclin L1 2.32135
ZZZ3 zinc finger, ZZ-type containing 3 2.32132
JAG2 jagged 2 2.32096
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.31958
KLK6 kallikrein-related peptidase 6 2.3184
KLF3 Kruppel-like factor 3 (basic) 2.31669
JMJD1C jumonji domain containing 1C 2.31459
GBE1 glucan (1,4-alpha-), branching enzyme 1 2.31283
KYAT3 kynurenine aminotransferase 3 2.31221
CD9 CD9 molecule 2.31165
NR1D1 nuclear receptor subfamily 1, group D, member 1 2.31131
VCPKMT valosin containing protein lysine (K) methyltransferase 2.30825
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.30774
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.30283
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 2.29929
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.29917
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 2.29778
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 2.29633
TEAD3 TEA domain family member 3 2.29434
MAPK12 mitogen-activated protein kinase 12 2.29315
AADAC arylacetamide deacetylase 2.28714
HLA-DRA major histocompatibility complex, class II, DR alpha 2.28612
ZDHHC18 zinc finger, DHHC-type containing 18 2.28478
ELL2 elongation factor, RNA polymerase II, 2 2.28438
ZNF451 zinc finger protein 451 2.28396
ZNF195 zinc finger protein 195 2.2833
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 2.27651
PPCS phosphopantothenoylcysteine synthetase 2.27571
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.272
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 2.26866
KIF5C kinesin family member 5C 2.26769
UBR4 ubiquitin protein ligase E3 component n-recognin 4 2.26262
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 2.26181
YIPF4 Yip1 domain family, member 4 2.25549
KLK8 kallikrein-related peptidase 8 2.25458
MUS81 MUS81 structure-specific endonuclease subunit 2.25429
CREB5 cAMP responsive element binding protein 5 2.25277
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.24779
MMP1 matrix metallopeptidase 1 2.24563
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.23934
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 2.2381
CREB1 cAMP responsive element binding protein 1 2.2355
VWF von Willebrand factor 2.2334
CAB39L calcium binding protein 39-like 2.23249
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 2.22912
ZFPM1 zinc finger protein, FOG family member 1 2.22835
CDC37L1 cell division cycle 37-like 1 2.22806
KCTD9 potassium channel tetramerization domain containing 9 2.22711
ANO10 anoctamin 10 2.21723
RNF24 ring finger protein 24 2.21663
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 2.21563
LMBR1L limb development membrane protein 1-like 2.21457
KAT6A K(lysine) acetyltransferase 6A 2.20697
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.20569
BRD1 bromodomain containing 1 2.20562
ATXN7 ataxin 7 2.20121
TRIM36 tripartite motif containing 36 2.20113
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 2.1959
CDKL3 cyclin-dependent kinase-like 3 2.19362
CLCA4 chloride channel accessory 4 2.19263
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 2.1921
UBXN7 UBX domain protein 7 2.19136
PLA2G2F phospholipase A2, group IIF 2.18978
ZNF574 zinc finger protein 574 2.18689
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.18491
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 2.18479
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 2.18031
ANXA11 annexin A11 2.18028
HSPG2 heparan sulfate proteoglycan 2 2.17986
KCNK5 potassium channel, two pore domain subfamily K, member 5 2.1771
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.17699
CSRNP2 cysteine-serine-rich nuclear protein 2 2.17679
ULK1 unc-51 like autophagy activating kinase 1 2.17545
CHKB choline kinase beta 2.17486
CTSD cathepsin D 2.17096
TLK2 tousled-like kinase 2 2.16838
IL36R interleukin 36 receptor 2.16717
LGALS9C lectin, galactoside-binding, soluble, 9C 2.1664
ZBTB35 zinc finger and BTB domain containing 35 2.16489
SLC38A2 solute carrier family 38, member 2 2.16476
POLR1E polymerase (RNA) I polypeptide E, 53kDa 2.16161
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 2.15871
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.15735
AVEN apoptosis, caspase activation inhibitor 2.15734
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.15336
FCMR Fc fragment of IgM receptor 2.15027
ZCCHC8 zinc finger, CCHC domain containing 8 2.14894
AIRIM AFG2 interacting ribosome maturation factor 2.14441
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 2.14086
ENOX1 ecto-NOX disulfide-thiol exchanger 1 2.14016
CHN1 chimerin 1 2.13666
RAB8B RAB8B, member RAS oncogene family 2.13624
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 2.13398
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 2.13387
MARS1 methionyl-tRNA synthetase 1 2.13093
THAP1 THAP domain containing, apoptosis associated protein 1 2.13005
ELOVL5 ELOVL fatty acid elongase 5 2.1283
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 2.12284
MBD1 methyl-CpG binding domain protein 1 2.12025
NANOS3 nanos homolog 3 (Drosophila) 2.12015
RHOC ras homolog family member C 2.11743
VEGFA vascular endothelial growth factor A 2.11291
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.11187
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.11029
CTTN cortactin 2.10835
TP53 tumor protein p53 2.10755
TCF25 transcription factor 25 (basic helix-loop-helix) 2.10602
KLF11 Kruppel-like factor 11 2.1054
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent 2.10503
PCDH1 protocadherin 1 2.10474
PSPC1 paraspeckle component 1 2.10189
MARF1 meiosis regulator and mRNA stability factor 1 2.09808
NAMPT nicotinamide phosphoribosyltransferase 2.09663
RND3 Rho family GTPase 3 2.09659
IER5 immediate early response 5 2.09546
CTNND1 catenin (cadherin-associated protein), delta 1 2.09478
RSRC2 arginine/serine-rich coiled-coil 2 2.09476
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 2.09316
LAPTM5 lysosomal protein transmembrane 5 2.09209
RABGGTB Rab geranylgeranyltransferase, beta subunit 2.09205
IL5 interleukin 5 2.09188
FRMD4B FERM domain containing 4B 2.09098
BMS1 BMS1 ribosome biogenesis factor 2.0907
RHOF ras homolog family member F (in filopodia) 2.08913
NT5E 5'-nucleotidase, ecto (CD73) 2.08739
ITCH itchy E3 ubiquitin protein ligase 2.08665
HBS1L HBS1-like translational GTPase 2.0865
ZFAND5 zinc finger, AN1-type domain 5 2.08553
TRIM33 tripartite motif containing 33 2.08147
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 2.07842
PGLYRP1 peptidoglycan recognition protein 1 2.07384
AMPD3 adenosine monophosphate deaminase 3 2.06807
FZD1 frizzled class receptor 1 2.06495
PUM3 pumilio RNA binding family member 3 2.06318
USP15 ubiquitin specific peptidase 15 2.06309
ELOVL1 ELOVL fatty acid elongase 1 2.06039
TMEM184B transmembrane protein 184B 2.0598
CGGBP1 CGG triplet repeat binding protein 1 2.05897
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 2.05885
IL18R1 interleukin 18 receptor 1 2.05822
PCGF1 polycomb group ring finger 1 2.05199
EPN3 epsin 3 2.05135
SEC14L1 SEC14-like 1 (S. cerevisiae) 2.05052
HPSE heparanase 2.05006
TSPAN15 tetraspanin 15 2.04905
RAB9A RAB9A, member RAS oncogene family 2.04886
ARHGAP10 Rho GTPase activating protein 10 2.048
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.04654
AUP1 ancient ubiquitous protein 1 2.04576
ZNF354A zinc finger protein 354A 2.04515
EIF5A2 eukaryotic translation initiation factor 5A2 2.04404
BGN biglycan 2.04335
MBD5 methyl-CpG binding domain protein 5 2.04295
ZBTB17 zinc finger and BTB domain containing 17 2.04295
ARL4C ADP-ribosylation factor-like 4C 2.04287
NOLC1 nucleolar and coiled-body phosphoprotein 1 2.04256
ARHGAP8 Rho GTPase activating protein 8 2.04237
FBXO7 F-box protein 7 2.04178
KLF9 Kruppel-like factor 9 2.03785
MMUT methylmalonyl-CoA mutase 2.03732
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.03729
ATG2B autophagy related 2B 2.0371
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.03688
SREK1IP1 SREK1-interacting protein 1 2.03492
ZNF536 zinc finger protein 536 2.03215
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 2.03122
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 2.03071
F2R coagulation factor II (thrombin) receptor 2.03055
SF3B1 splicing factor 3b, subunit 1, 155kDa 2.02998
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 2.02826
ZSCAN9 zinc finger and SCAN domain containing 9 2.02767
ZBTB43 zinc finger and BTB domain containing 43 2.02751
CST7 cystatin F (leukocystatin) 2.02662
PDCD10 programmed cell death 10 2.02614
ZNF148 zinc finger protein 148 2.02509
IL37 interleukin 37 2.02269
PCNP PEST proteolytic signal containing nuclear protein 2.02223
WDR44 WD repeat domain 44 2.02066
FBXO28 F-box protein 28 2.01837
ZNF12 zinc finger protein 12 2.01781
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa 2.01687
PHF1 PHD finger protein 1 2.01605
H2AC25 H2A clustered histone 25 2.01541
CCNT2 cyclin T2 2.01285
RNF25 ring finger protein 25 2.01111
RASA2 RAS p21 protein activator 2 2.01053
ANGPT2 angiopoietin 2 2.00875
CLCF1 cardiotrophin-like cytokine factor 1 2.00725
GNL1 guanine nucleotide binding protein-like 1 2.00648
IL2RA interleukin 2 receptor, alpha 2.00473
GPKOW G patch domain and KOW motifs 2.00407
POGK pogo transposable element with KRAB domain 2.00339
MED15 mediator complex subunit 15 2.00268
TRAPPC14 trafficking protein particle complex subunit 14 2.0021
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 2.00152
RAB21 RAB21, member RAS oncogene family 2.00078

decreased expression

Symbol Name Standardized Value
BLCAP bladder cancer associated protein -10.0
B4GAT1 beta-1,4-glucuronyltransferase 1 -10.0
CD320 CD320 molecule -10.0
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -9.68524
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -9.02872
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -8.76792
HSPB1 heat shock 27kDa protein 1 -8.63023
TCTN1 tectonic family member 1 -8.62307
MELK maternal embryonic leucine zipper kinase -8.5837
PLK1 polo-like kinase 1 -8.13348
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -8.0646
LBR lamin B receptor -7.80972
CDC20 cell division cycle 20 -7.78947
HACD3 3-hydroxyacyl-CoA dehydratase 3 -7.75199
PGAM4 phosphoglycerate mutase family member 4 -7.55893
CCNA2 cyclin A2 -7.55159
TWF2 twinfilin actin binding protein 2 -7.48349
STMN1 stathmin 1 -7.35446
PROS1 protein S (alpha) -7.33697
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -7.23149
ZNF274 zinc finger protein 274 -7.159
PARP1 poly (ADP-ribose) polymerase 1 -7.06877
AURKB aurora kinase B -7.01295
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -7.00866
PSRC1 proline/serine-rich coiled-coil 1 -6.97371
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -6.97034
CCNB1 cyclin B1 -6.9603
INTS3 integrator complex subunit 3 -6.9542
PCCB propionyl CoA carboxylase, beta polypeptide -6.89221
UBE2C ubiquitin-conjugating enzyme E2C -6.86402
TOP2A topoisomerase (DNA) II alpha 170kDa -6.85161
PRCP prolylcarboxypeptidase (angiotensinase C) -6.76193
CDK1 cyclin-dependent kinase 1 -6.73305
THAP11 THAP domain containing 11 -6.7107
ADI1 acireductone dioxygenase 1 -6.68333
BIRC5 baculoviral IAP repeat containing 5 -6.61357
NT5DC2 5'-nucleotidase domain containing 2 -6.59439
HMGA2 high mobility group AT-hook 2 -6.51407
TARBP1 TAR (HIV-1) RNA binding protein 1 -6.41998
POLR1A polymerase (RNA) I polypeptide A, 194kDa -6.40437
PCNA proliferating cell nuclear antigen -6.28146
CDC25B cell division cycle 25B -6.14982
ZW10 zw10 kinetochore protein -6.1494
RUVBL1 RuvB-like AAA ATPase 1 -5.95519
NUP85 nucleoporin 85kDa -5.84572
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -5.73784
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -5.72486
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -5.72257
TLR4 toll-like receptor 4 -5.67518
TMEM109 transmembrane protein 109 -5.56329
DERA deoxyribose-phosphate aldolase (putative) -5.44461
ALDOC aldolase C, fructose-bisphosphate -5.42004
ECH1 enoyl CoA hydratase 1, peroxisomal -5.4114
UBE3C ubiquitin protein ligase E3C -5.35934
GNAS GNAS complex locus -5.3431
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -5.32281
HSPA1A heat shock 70kDa protein 1A -5.27028
MLEC malectin -5.25196
GTF2A2 general transcription factor IIA, 2, 12kDa -5.18996
GET1 guided entry of tail-anchored proteins factor 1 -5.15874
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -5.14521
ANKRD10 ankyrin repeat domain 10 -5.1321
COG7 component of oligomeric golgi complex 7 -5.10198
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -5.03596
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -5.03078
TRAPPC3 trafficking protein particle complex 3 -4.92495
ASF1B anti-silencing function 1B histone chaperone -4.84197
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -4.84122
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -4.83995
PGM1 phosphoglucomutase 1 -4.80551
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -4.67147
MCM10 minichromosome maintenance complex component 10 -4.67026
TPM1 tropomyosin 1 (alpha) -4.66793
CBR1 carbonyl reductase 1 -4.64474
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -4.55385
CHEK1 checkpoint kinase 1 -4.552
ERBB2 erb-b2 receptor tyrosine kinase 2 -4.54684
TFDP1 transcription factor Dp-1 -4.53658
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -4.53092
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -4.51324
KIF11 kinesin family member 11 -4.51213
NENF neudesin neurotrophic factor -4.47471
CRYZ crystallin, zeta (quinone reductase) -4.31114
NFIL3 nuclear factor, interleukin 3 regulated -4.2821
KIF4A kinesin family member 4A -4.2534
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -4.21861
CDK4 cyclin-dependent kinase 4 -4.20729
PEG10 paternally expressed 10 -4.17937
AURKA aurora kinase A -4.17609
DDB2 damage-specific DNA binding protein 2, 48kDa -4.14386
TSPAN4 tetraspanin 4 -4.13377
TRIP13 thyroid hormone receptor interactor 13 -4.0574
COPS7A COP9 signalosome subunit 7A -3.99062
PRPF4 pre-mRNA processing factor 4 -3.87574
SCARB1 scavenger receptor class B, member 1 -3.8529
TXLNA taxilin alpha -3.82807
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.78744
CCNB2 cyclin B2 -3.76679
COG4 component of oligomeric golgi complex 4 -3.75958
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -3.7446
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.73872
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.7374
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -3.70773
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -3.70521
PTTG1 pituitary tumor-transforming 1 -3.69827
CD58 CD58 molecule -3.68945
MRPL12 mitochondrial ribosomal protein L12 -3.67394
TMEM97 transmembrane protein 97 -3.6532
NLRP2B NLR family pyrin domain containing 2B -3.64877
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -3.63595
NUP62 nucleoporin 62kDa -3.63301
CCND3 cyclin D3 -3.62067
DEXI Dexi homolog (mouse) -3.60789
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -3.60211
GINS1 GINS complex subunit 1 (Psf1 homolog) -3.54761
KIF14 kinesin family member 14 -3.54125
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.53491
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -3.53288
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -3.52855
PRUNE1 prune exopolyphosphatase 1 -3.52725
BBS1 Bardet-Biedl syndrome 1 -3.51776
SKIC8 SKI8 subunit of superkiller complex -3.46044
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.45968
CDKN3 cyclin-dependent kinase inhibitor 3 -3.44023
TMEM106C transmembrane protein 106C -3.43596
TSEN2 TSEN2 tRNA splicing endonuclease subunit -3.42711
MSH6 mutS homolog 6 -3.42491
AMDHD2 amidohydrolase domain containing 2 -3.40413
SNF8 SNF8, ESCRT-II complex subunit -3.404
CHAF1A chromatin assembly factor 1, subunit A (p150) -3.3954
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.38417
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -3.36006
TLCD3A TLC domain containing 3A -3.351
ZMIZ1 zinc finger, MIZ-type containing 1 -3.35037
MAGED1 melanoma antigen family D1 -3.34685
FIRRM FIGNL1 interacting regulator of recombination and mitosis -3.34616
GAA glucosidase, alpha; acid -3.3384
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.3292
TK1 thymidine kinase 1, soluble -3.3238
ABHD14A abhydrolase domain containing 14A -3.31683
RBM14-RBM4 RBM14-RBM4 readthrough -3.29793
TRAP1 TNF receptor-associated protein 1 -3.28147
MRPL11 mitochondrial ribosomal protein L11 -3.27739
GEMIN6 gem (nuclear organelle) associated protein 6 -3.26048
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.25713
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -3.23782
LAGE3 L antigen family, member 3 -3.2364
FKBP3 FK506 binding protein 3, 25kDa -3.2362
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -3.23129
DHFR dihydrofolate reductase -3.22704
CETN3 centrin, EF-hand protein, 3 -3.21503
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -3.1847
FEN1 flap structure-specific endonuclease 1 -3.18031
MYCBP MYC binding protein -3.17455
SEPHS1 selenophosphate synthetase 1 -3.15958
FUCA1 fucosidase, alpha-L- 1, tissue -3.15344
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -3.14616
NCAPG2 non-SMC condensin II complex, subunit G2 -3.14059
STAT1 signal transducer and activator of transcription 1, 91kDa -3.13137
RNASE7 ribonuclease, RNase A family, 7 -3.12962
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.1251
SPDL1 spindle apparatus coiled-coil protein 1 -3.1224
RPA3 replication protein A3, 14kDa -3.11434
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -3.07666
CDCA3 cell division cycle associated 3 -3.03918
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.03667
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -3.03508
TRMT5 tRNA methyltransferase 5 -3.03421
DNAAF2 dynein, axonemal, assembly factor 2 -3.01478
USP6NL USP6 N-terminal like -3.01086
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.99914
LMAN2L lectin, mannose-binding 2-like -2.99622
SOAT2 sterol O-acyltransferase 2 -2.98499
PDIA5 protein disulfide isomerase family A, member 5 -2.98323
TACC3 transforming, acidic coiled-coil containing protein 3 -2.97657
MSH2 mutS homolog 2 -2.97211
HYOU1 hypoxia up-regulated 1 -2.97022
GALE UDP-galactose-4-epimerase -2.96644
SCCPDH saccharopine dehydrogenase (putative) -2.96562
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.95829
MGST2 microsomal glutathione S-transferase 2 -2.95759
PPY pancreatic polypeptide -2.95502
ISOC2 isochorismatase domain containing 2 -2.94388
RXYLT1 ribitol xylosyltransferase 1 -2.93079
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.92462
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.91727
PDIA4 protein disulfide isomerase family A, member 4 -2.9155
CENPA centromere protein A -2.90285
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.89615
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.88891
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.88317
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -2.88049
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.87892
TBC1D10C TBC1 domain family, member 10C -2.87886
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -2.8758
LUM lumican -2.87532
RFC3 replication factor C (activator 1) 3, 38kDa -2.87415
HSPA14 heat shock 70kDa protein 14 -2.87128
TSEN34 TSEN34 tRNA splicing endonuclease subunit -2.8701
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.86867
WASHC3 WASH complex subunit 3 -2.85701
NELFCD negative elongation factor complex member C/D -2.85043
ATP5IF1 ATP synthase inhibitory factor subunit 1 -2.84429
QDPR quinoid dihydropteridine reductase -2.84368
DCPS decapping enzyme, scavenger -2.84228
WDR77 WD repeat domain 77 -2.84218
PLA2G15 phospholipase A2, group XV -2.83437
KIF15 kinesin family member 15 -2.81456
RPIA ribose 5-phosphate isomerase A -2.81172
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.8039
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -2.80039
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -2.79865
DSCC1 DNA replication and sister chromatid cohesion 1 -2.79143
DUT deoxyuridine triphosphatase -2.78846
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.77919
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -2.77662
MRPS7 mitochondrial ribosomal protein S7 -2.77326
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -2.77198
G6PC3 glucose 6 phosphatase, catalytic, 3 -2.77055
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.76816
UXT ubiquitously-expressed, prefoldin-like chaperone -2.76551
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.76349
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.75977
RRM2 ribonucleotide reductase M2 -2.75844
NUP210 nucleoporin 210kDa -2.75233
TMX1 thioredoxin-related transmembrane protein 1 -2.74475
CSF3R colony stimulating factor 3 receptor (granulocyte) -2.73898
MDH1 malate dehydrogenase 1, NAD (soluble) -2.72346
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.72313
CDKN2A cyclin-dependent kinase inhibitor 2A -2.72117
KIF18B kinesin family member 18B -2.72042
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.7166
HMGB2 high mobility group box 2 -2.71124
TRAPPC4 trafficking protein particle complex 4 -2.69965
ZWINT ZW10 interacting kinetochore protein -2.6944
CETN2 centrin, EF-hand protein, 2 -2.69154
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.68577
ICMT isoprenylcysteine carboxyl methyltransferase -2.67681
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.6758
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -2.67561
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.66091
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.66036
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.65806
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.65638
HNMT histamine N-methyltransferase -2.65147
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle -2.6503
PYCR1 pyrroline-5-carboxylate reductase 1 -2.6414
AKAP8 A kinase (PRKA) anchor protein 8 -2.64095
MAT2A methionine adenosyltransferase II, alpha -2.63974
PEBP1 phosphatidylethanolamine binding protein 1 -2.63683
GALK1 galactokinase 1 -2.63516
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.63494
TMPRSS6 transmembrane protease, serine 6 -2.63197
ZNF83 zinc finger protein 83 -2.63116
RBM4B RNA binding motif protein 4B -2.62562
GSTM2 glutathione S-transferase mu 2 (muscle) -2.61787
ZNF318 zinc finger protein 318 -2.61573
ERH enhancer of rudimentary homolog (Drosophila) -2.615
BMP4 bone morphogenetic protein 4 -2.61028
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.60007
CRLF1 cytokine receptor-like factor 1 -2.59669
CDCA8 cell division cycle associated 8 -2.59625
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.59516
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -2.59329
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.58572
GPD1L glycerol-3-phosphate dehydrogenase 1-like -2.58449
GTPBP3 GTP binding protein 3 (mitochondrial) -2.57625
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.57506
PEPD peptidase D -2.57378
SPDEF SAM pointed domain containing ETS transcription factor -2.56207
NEK11 NIMA-related kinase 11 -2.55749
PGRMC1 progesterone receptor membrane component 1 -2.55716
OIP5 Opa interacting protein 5 -2.55519
HADH hydroxyacyl-CoA dehydrogenase -2.55048
INCENP inner centromere protein antigens 135/155kDa -2.54994
ETFB electron-transfer-flavoprotein, beta polypeptide -2.54663
UBE2A ubiquitin-conjugating enzyme E2A -2.54515
MANF mesencephalic astrocyte-derived neurotrophic factor -2.54496
STIMATE STIM activating enhancer -2.54137
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 -2.53753
COMMD9 COMM domain containing 9 -2.53701
HDAC1 histone deacetylase 1 -2.53584
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.5292
KIFC1 kinesin family member C1 -2.52763
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.52242
GTF2H5 general transcription factor IIH, polypeptide 5 -2.52063
CYB5R1 cytochrome b5 reductase 1 -2.52057
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -2.51262
AMT aminomethyltransferase -2.50752
MIS18A MIS18 kinetochore protein A -2.50374
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.50334
HEXB hexosaminidase B (beta polypeptide) -2.49838
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.49838
ACOX2 acyl-CoA oxidase 2, branched chain -2.49312
LGMN legumain -2.48538
SCGB1D1 secretoglobin, family 1D, member 1 -2.48502
TM9SF3 transmembrane 9 superfamily member 3 -2.48313
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.48033
GAMT guanidinoacetate N-methyltransferase -2.46939
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) -2.46311
ZSCAN5A zinc finger and SCAN domain containing 5A -2.46271
FOXA2 forkhead box A2 -2.4608
RMI1 RecQ mediated genome instability 1 -2.46054
ZNF106 zinc finger protein 106 -2.46038
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.45759
FANCI Fanconi anemia, complementation group I -2.45562
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -2.45182
BANF1 barrier to autointegration factor 1 -2.45145
PYGL phosphorylase, glycogen, liver -2.44182
CDC25A cell division cycle 25A -2.44173
RPAP1 RNA polymerase II associated protein 1 -2.44067
NCAPH non-SMC condensin I complex, subunit H -2.43781
ARHGAP1 Rho GTPase activating protein 1 -2.43462
CAPZB capping protein (actin filament) muscle Z-line, beta -2.43401
CDC6 cell division cycle 6 -2.43096
ZMYM4 zinc finger, MYM-type 4 -2.42326
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.42251
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.41958
HMGN2 high mobility group nucleosomal binding domain 2 -2.41805
RIDA reactive intermediate imine deaminase A homolog -2.41245
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.40253
TG thyroglobulin -2.39592
TPX2 TPX2, microtubule-associated -2.39136
CCDC86 coiled-coil domain containing 86 -2.3854
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -2.38372
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -2.38179
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.37916
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -2.37665
LRRC61 leucine rich repeat containing 61 -2.37325
IL6 interleukin 6 -2.37254
MCM4 minichromosome maintenance complex component 4 -2.37238
DNAAF11 dynein axonemal assembly factor 11 -2.37212
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -2.36546
TCTN2 tectonic family member 2 -2.36503
NEK2 NIMA-related kinase 2 -2.36077
NFS1 NFS1 cysteine desulfurase -2.35978
CTSB cathepsin B -2.35838
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.35773
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -2.35771
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -2.35769
C2CD5 C2 calcium-dependent domain containing 5 -2.35338
TEDC2 tubulin epsilon and delta complex 2 -2.34579
PLA2G2D phospholipase A2, group IID -2.34021
ACP2 acid phosphatase 2, lysosomal -2.33981
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -2.33834
EXOSC9 exosome component 9 -2.33757
ITGB1BP1 integrin beta 1 binding protein 1 -2.33633
CENPS-CORT CENPS-CORT readthrough -2.32533
CD70 CD70 molecule -2.32502
INTS9 integrator complex subunit 9 -2.32488
SORD sorbitol dehydrogenase -2.32459
PARN poly(A)-specific ribonuclease -2.32377
EMC9 ER membrane protein complex subunit 9 -2.32218
GLT8D1 glycosyltransferase 8 domain containing 1 -2.322
TBC1D16 TBC1 domain family, member 16 -2.31644
CALCA calcitonin-related polypeptide alpha -2.31466
ZDHHC6 zinc finger, DHHC-type containing 6 -2.31311
ITGA7 integrin, alpha 7 -2.30835
GLRX glutaredoxin (thioltransferase) -2.30787
QTRT1 queuine tRNA-ribosyltransferase 1 -2.30759
THOP1 thimet oligopeptidase 1 -2.30718
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) -2.29866
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.29858
FOXM1 forkhead box M1 -2.29644
ADISSP adipose secreted signaling protein -2.29188
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.29054
IGSF1 immunoglobulin superfamily, member 1 -2.2878
SHCBP1 SHC SH2-domain binding protein 1 -2.28773
CALCB calcitonin-related polypeptide beta -2.28494
TATDN2 TatD DNase domain containing 2 -2.28436
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -2.28426
SDF2L1 stromal cell-derived factor 2-like 1 -2.27568
MTARC1 mitochondrial amidoxime reducing component 1 -2.27562
NR1H3 nuclear receptor subfamily 1, group H, member 3 -2.27451
COA3 cytochrome c oxidase assembly factor 3 -2.27267
MRPS31 mitochondrial ribosomal protein S31 -2.27071
LONP2 lon peptidase 2, peroxisomal -2.2707
MFSD1 major facilitator superfamily domain containing 1 -2.2682
MREG melanoregulin -2.26758
KRT85 keratin 85, type II -2.26636
CFAP69 cilia and flagella associated protein 69 -2.26507
SIRT3 sirtuin 3 -2.26435
OSBPL11 oxysterol binding protein-like 11 -2.26353
HMG20B high mobility group 20B -2.26259
CEP55 centrosomal protein 55kDa -2.26159
H2AX H2A.X variant histone -2.25968
MRNIP MRN complex interacting protein -2.25927
ABI3BP ABI family, member 3 (NESH) binding protein -2.25856
TCTN3 tectonic family member 3 -2.25638
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -2.25562
ARID3A AT rich interactive domain 3A (BRIGHT-like) -2.25329
CBR4 carbonyl reductase 4 -2.24726
ZCCHC24 zinc finger, CCHC domain containing 24 -2.24671
SRSF1 serine/arginine-rich splicing factor 1 -2.24401
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -2.24388
PXMP2 peroxisomal membrane protein 2, 22kDa -2.24329
HMGN3 high mobility group nucleosomal binding domain 3 -2.23933
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -2.23731
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.23724
NASP nuclear autoantigenic sperm protein (histone-binding) -2.23519
CDIP1 cell death-inducing p53 target 1 -2.2305
FAM174B family with sequence similarity 174, member B -2.22887
ATP5MF ATP synthase membrane subunit f -2.22849
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.22779
ERLIN2 ER lipid raft associated 2 -2.22213
ASB9 ankyrin repeat and SOCS box containing 9 -2.21847
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -2.21821
ACAA2 acetyl-CoA acyltransferase 2 -2.21528
AGO4 argonaute RISC catalytic component 4 -2.2152
MRPL19 mitochondrial ribosomal protein L19 -2.21441
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.21364
KDM1A lysine (K)-specific demethylase 1A -2.20953
ZNF747 zinc finger protein 747 -2.20876
ATP5PD ATP synthase peripheral stalk subunit d -2.20792
RACGAP1 Rac GTPase activating protein 1 -2.20603
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.19406
GSTM5 glutathione S-transferase mu 5 -2.19328
UROS uroporphyrinogen III synthase -2.18934
TSPAN6 tetraspanin 6 -2.18837
HTD2 hydroxyacyl-thioester dehydratase type 2 -2.18528
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.1839
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 -2.18382
ANAPC15 anaphase promoting complex subunit 15 -2.18275
PYCR3 pyrroline-5-carboxylate reductase 3 -2.1813
ZNF528 zinc finger protein 528 -2.17579
TMEM14A transmembrane protein 14A -2.17556
ANGPTL8 angiopoietin like 8 -2.17293
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -2.17141
ASGR1 asialoglycoprotein receptor 1 -2.1688
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -2.16499
LOC124907782 dual specificity protein phosphatase 22 -2.1578
PRPF31 pre-mRNA processing factor 31 -2.15646
RPS27L ribosomal protein S27-like -2.15278
BBOF1 basal body orientation factor 1 -2.15267
IQGAP2 IQ motif containing GTPase activating protein 2 -2.14793
NISCH nischarin -2.14783
CADPS2 Ca++-dependent secretion activator 2 -2.14672
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 -2.14538
TTC38 tetratricopeptide repeat domain 38 -2.13976
RAD51C RAD51 paralog C -2.13493
MAP2K6 mitogen-activated protein kinase kinase 6 -2.13463
SNX1 sorting nexin 1 -2.13204
NXT2 nuclear transport factor 2-like export factor 2 -2.13183
RPL26L1 ribosomal protein L26-like 1 -2.12912
CDK5 cyclin-dependent kinase 5 -2.12736
CENPX centromere protein X -2.12579
RIBC2 RIB43A domain with coiled-coils 2 -2.1252
ICAM3 intercellular adhesion molecule 3 -2.11648
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -2.11336
SMG6 SMG6 nonsense mediated mRNA decay factor -2.11236
MYO5C myosin VC -2.10819
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.10409
DNAAF5 dynein, axonemal, assembly factor 5 -2.10301
WRAP53 WD repeat containing, antisense to TP53 -2.10248
CENPM centromere protein M -2.10199
CSAD cysteine sulfinic acid decarboxylase -2.10035
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.09533
EEA1 early endosome antigen 1 -2.09447
DYNLL1 dynein, light chain, LC8-type 1 -2.09418
CDK2 cyclin-dependent kinase 2 -2.08721
LOC100533997 MAGEA10-MAGEA5 readthrough -2.08711
CENPE centromere protein E, 312kDa -2.08672
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -2.0865
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta -2.08553
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.08533
LIPG lipase, endothelial -2.08517
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 -2.08411
ACYP1 acylphosphatase 1, erythrocyte (common) type -2.08238
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -2.0802
FAM111A family with sequence similarity 111, member A -2.07669
CCDC92 coiled-coil domain containing 92 -2.0766
CER1 cerberus 1, DAN family BMP antagonist -2.07623
SPC25 SPC25, NDC80 kinetochore complex component -2.07577
TMPO thymopoietin -2.07469
NCAPD2 non-SMC condensin I complex, subunit D2 -2.0743
ACAA1 acetyl-CoA acyltransferase 1 -2.07194
DEPDC1 DEP domain containing 1 -2.06453
BCL7C B-cell CLL/lymphoma 7C -2.06402
LMNB1 lamin B1 -2.06039
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -2.05682
UBE2S ubiquitin-conjugating enzyme E2S -2.05668
NNT nicotinamide nucleotide transhydrogenase -2.05427
METTL9 methyltransferase like 9 -2.05233
IFT81 intraflagellar transport 81 -2.05211
SAP30 Sin3A-associated protein, 30kDa -2.05118
CREG1 cellular repressor of E1A-stimulated genes 1 -2.05064
MRPL34 mitochondrial ribosomal protein L34 -2.05031
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -2.04457
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 -2.04446
UNG uracil-DNA glycosylase -2.04102
TSNAXIP1 translin-associated factor X interacting protein 1 -2.0408
RBBP4 retinoblastoma binding protein 4 -2.03761
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -2.03663
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.03428
LOC102724652 alpha-crystallin A chain -2.03286
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.02983
SIGLEC9 sialic acid binding Ig-like lectin 9 -2.02946
CCNO cyclin O -2.02913
SMC1A structural maintenance of chromosomes 1A -2.02784
HAUS7 HAUS augmin-like complex, subunit 7 -2.02751
CALM3 calmodulin 3 (phosphorylase kinase, delta) -2.0274
PFN1 profilin 1 -2.02371
SMCO4 single-pass membrane protein with coiled-coil domains 4 -2.02041
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.02013
COX11 COX11 cytochrome c oxidase copper chaperone -2.01945
LMBR1 limb development membrane protein 1 -2.01768
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -2.01576
CFAP20 cilia and flagella associated protein 20 -2.01403
UXS1 UDP-glucuronate decarboxylase 1 -2.01364
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit -2.01359
ZNF835 zinc finger protein 835 -2.01205
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.01199
CHAD chondroadherin -2.00559
TFAM transcription factor A, mitochondrial -2.00486
F7 coagulation factor VII (serum prothrombin conversion accelerator) -2.00435
GYG2 glycogenin 2 -2.00015