CRCGN009_HEPG2_24H:L11 Gene Set
Genes
65 genes differentially expressed following the CRCGN009_HEPG2_24H:L11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
6.63754
|
|
IDE
|
insulin-degrading enzyme
|
5.75808
|
|
SQOR
|
sulfide quinone oxidoreductase
|
5.54708
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.28807
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.10904
|
|
MSRA
|
methionine sulfoxide reductase A
|
3.78354
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.69515
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.60161
|
|
MYLK
|
myosin light chain kinase
|
3.23847
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.15487
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.89751
|
|
MAP7
|
microtubule-associated protein 7
|
2.78393
|
|
SNX7
|
sorting nexin 7
|
2.73141
|
|
GATA2
|
GATA binding protein 2
|
2.60227
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.59506
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.55373
|
|
PRKCH
|
protein kinase C, eta
|
2.54026
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.5048
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.3477
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.34389
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.34364
|
|
JADE2
|
jade family PHD finger 2
|
2.24966
|
|
EIF4EBP1
|
eukaryotic translation initiation factor 4E binding protein 1
|
2.14762
|
|
ZNF589
|
zinc finger protein 589
|
2.13641
|
|
SIRT3
|
sirtuin 3
|
2.10752
|
|
ADGRG1
|
adhesion G protein-coupled receptor G1
|
2.09615
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
2.08674
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
2.04401
|
|
TBC1D31
|
TBC1 domain family, member 31
|
2.01079
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.14956
|
|
CCNB2
|
cyclin B2
|
-4.84488
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-4.40505
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.18524
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.07504
|
|
DNM1L
|
dynamin 1-like
|
-4.06794
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.86837
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.74358
|
|
ZNF586
|
zinc finger protein 586
|
-3.65567
|
|
EGF
|
epidermal growth factor
|
-3.56498
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-3.56062
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.52185
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.40159
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.28699
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.26405
|
|
GOLT1B
|
golgi transport 1B
|
-3.19443
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.05444
|
|
FHL2
|
four and a half LIM domains 2
|
-3.0447
|
|
TCTN1
|
tectonic family member 1
|
-3.01419
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.85741
|
|
PEG10
|
paternally expressed 10
|
-2.84654
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.80557
|
|
PGM1
|
phosphoglucomutase 1
|
-2.7229
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.68932
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.63871
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.63781
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.40891
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.37922
|
|
GNAS
|
GNAS complex locus
|
-2.20383
|
|
TRAPPC6A
|
trafficking protein particle complex 6A
|
-2.19117
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.18602
|
|
ZNF135
|
zinc finger protein 135
|
-2.18286
|
|
TLR4
|
toll-like receptor 4
|
-2.13956
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.09136
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.04831
|
|
TCF21
|
transcription factor 21
|
-2.03892
|
