| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | ethinyl estradiol 19.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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72 genes differentially expressed following the CRCGN009_HEPG2_24H:L14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 6.81891 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 6.76003 |
| H2BC12 | H2B clustered histone 12 | 4.38525 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.84966 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.81155 |
| MOK | MOK protein kinase | 3.74003 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.73721 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.52338 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.46105 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.23259 |
| KLHL9 | kelch-like family member 9 | 3.16689 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.11939 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.09164 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.03856 |
| JADE2 | jade family PHD finger 2 | 2.85688 |
| UFM1 | ubiquitin-fold modifier 1 | 2.82995 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.74813 |
| MEF2C | myocyte enhancer factor 2C | 2.74806 |
| RALGDS | ral guanine nucleotide dissociation stimulator | 2.59686 |
| HSPA1A | heat shock 70kDa protein 1A | 2.40788 |
| SCRN1 | secernin 1 | 2.38294 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.30648 |
| KIFBP | kinesin family binding protein | 2.30524 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.29211 |
| ABHD4 | abhydrolase domain containing 4 | 2.24883 |
| SESN1 | sestrin 1 | 2.21236 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.18677 |
| BAX | BCL2-associated X protein | 2.17355 |
| COG7 | component of oligomeric golgi complex 7 | 2.16303 |
| TPD52L2 | tumor protein D52-like 2 | 2.1335 |
| LRP10 | low density lipoprotein receptor-related protein 10 | 2.07405 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 2.07293 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.03433 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -6.76395 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -6.4343 |
| MELK | maternal embryonic leucine zipper kinase | -4.75697 |
| CDK1 | cyclin-dependent kinase 1 | -4.63422 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -4.30265 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.15858 |
| CDC25B | cell division cycle 25B | -4.14885 |
| TLR4 | toll-like receptor 4 | -4.10812 |
| AURKB | aurora kinase B | -4.07871 |
| ADI1 | acireductone dioxygenase 1 | -3.75798 |
| CDC20 | cell division cycle 20 | -3.74068 |
| CCNB1 | cyclin B1 | -3.71518 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.61468 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -3.40623 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -3.18109 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.16777 |
| LDHD | lactate dehydrogenase D | -3.01036 |
| HADH | hydroxyacyl-CoA dehydrogenase | -2.9602 |
| PCNA | proliferating cell nuclear antigen | -2.85776 |
| PGM1 | phosphoglucomutase 1 | -2.82031 |
| TLCD3A | TLC domain containing 3A | -2.76286 |
| CCNB2 | cyclin B2 | -2.72988 |
| FASTKD5 | FAST kinase domains 5 | -2.69283 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.61824 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -2.61728 |
| COPS7A | COP9 signalosome subunit 7A | -2.55809 |
| DCK | deoxycytidine kinase | -2.42112 |
| ICAM3 | intercellular adhesion molecule 3 | -2.40944 |
| PLK1 | polo-like kinase 1 | -2.27547 |
| GALE | UDP-galactose-4-epimerase | -2.18666 |
| STMN1 | stathmin 1 | -2.12336 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.10367 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -2.09833 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -2.08736 |
| FOXM1 | forkhead box M1 | -2.05543 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -2.05246 |
| CDCA8 | cell division cycle associated 8 | -2.04375 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -2.04277 |
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | -2.02479 |
